A. Vignola, F. Mirabella, G. Costanzo, D. Giorgi, R. Gjomarkaj et al., Airway Remodeling in Asthma, Chest, vol.123, issue.3, pp.417-422, 2003.
DOI : 10.1378/chest.123.3_suppl.417S

A. Vignola, J. Kips, and J. Bousquet, Tissue remodeling as a feature of persistent asthma, Journal of Allergy and Clinical Immunology, vol.105, issue.6, pp.1041-1053, 2000.
DOI : 10.1067/mai.2000.107195

L. Benayoun, A. Druilhe, M. Dombret, M. Aubier, and M. Pretolani, Airway Structural Alterations Selectively Associated with Severe Asthma, American Journal of Respiratory and Critical Care Medicine, vol.167, issue.10, pp.1360-1368, 2003.
DOI : 10.1164/rccm.200209-1030OC

Y. Sumi and Q. Hamid, Airway Remodeling in Asthma, Allergology International, vol.56, issue.4, pp.341-348, 2007.
DOI : 10.2332/allergolint.R-07-153

W. Roche, R. Beasley, J. Williams, and S. Holgate, SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS, The Lancet, vol.333, issue.8637, pp.520-524, 1989.
DOI : 10.1016/S0140-6736(89)90067-6

K. Parameswaran, A. Willems-widyastuti, V. Alagappan, K. Radford, A. Kranenburg et al., Role of Extracellular Matrix and Its Regulators in Human Airway Smooth Muscle Biology, Cell Biochemistry and Biophysics, vol.44, issue.1, pp.139-146, 2006.
DOI : 10.1385/CBB:44:1:139

E. Minshall, D. Leung, R. Martin, Y. Song, L. Cameron et al., mRNA Expression and Airways Fibrosis in Bronchial Asthma, American Journal of Respiratory Cell and Molecular Biology, vol.17, issue.3, pp.326-333, 1997.
DOI : 10.1165/ajrcmb.17.3.2733

P. Flood-page, A. Menzies-gow, S. Phipps, S. Ying, A. Wangoo et al., Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics, Journal of Clinical Investigation, vol.112, issue.7, pp.1029-1036, 2003.
DOI : 10.1172/JCI17974

A. Vignola, P. Chanez, G. Chiappara, A. Merendino, E. Pace et al., Transforming Growth Factor- ?? Expression in Mucosal Biopsies in Asthma and Chronic Bronchitis, American Journal of Respiratory and Critical Care Medicine, vol.156, issue.2, pp.591-599, 1997.
DOI : 10.1164/ajrccm.156.2.9609066

E. Minshall, J. Chakir, M. Laviolette, S. Molet, Z. Zhu et al., IL-11 expression is increased in severe asthma: Association with epithelial cells and eosinophils, Journal of Allergy and Clinical Immunology, vol.105, issue.2, pp.232-238, 2000.
DOI : 10.1016/S0091-6749(00)90070-8

J. Cho, M. Miller, K. Baek, J. Han, J. Nayar et al., Inhibition of airway remodeling in IL-5???deficient mice, Journal of Clinical Investigation, vol.113, issue.4, pp.551-560, 2004.
DOI : 10.1172/JCI19133

P. Flood-page, A. Menzies-gow, A. Kay, and D. Robinson, Eosinophil's Role Remains Uncertain as Anti???Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway, American Journal of Respiratory and Critical Care Medicine, vol.167, issue.2, pp.199-204, 2003.
DOI : 10.1164/rccm.200208-789OC

A. Barczyk, W. Pierzchala, and E. Sozanska, Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine, Respiratory Medicine, vol.97, issue.6, pp.726-733, 2003.
DOI : 10.1053/rmed.2003.1507

N. Oda, P. Canelos, D. Essayan, B. Plunkett, A. Myers et al., Interleukin-17F Induces Pulmonary Neutrophilia and Amplifies Antigen-induced Allergic Response, American Journal of Respiratory and Critical Care Medicine, vol.171, issue.1, pp.12-18, 2005.
DOI : 10.1164/rccm.200406-778OC

Y. Chang, L. Al-alwan, P. Risse, L. Roussel, S. Rousseau et al., TH17 cytokines induce human airway smooth muscle cell migration, Journal of Allergy and Clinical Immunology, vol.127, issue.4, pp.1046-1053, 2011.
DOI : 10.1016/j.jaci.2010.12.1117

P. Cheung, C. Wong, and C. Lam, Molecular Mechanisms of Cytokine and Chemokine Release from Eosinophils Activated by IL-17A, IL-17F, and IL-23: Implication for Th17 Lymphocytes-Mediated Allergic Inflammation, The Journal of Immunology, vol.180, issue.8, pp.5625-5635, 2008.
DOI : 10.4049/jimmunol.180.8.5625

G. Dubois, R. Schweizer, C. Versluis, C. Bruijnzeel-koomen, and P. Bruijnzeel, Human Eosinophils Constitutively Express a Functional Interleukin-4 Receptor: Interleukin-4??????Induced Priming of Chemotactic Responses and Induction of PI-3 Kinase Activity, American Journal of Respiratory Cell and Molecular Biology, vol.19, issue.4, pp.691-699, 1998.
DOI : 10.1165/ajrcmb.19.4.3208

D. Riedel, A. Lindemann, M. Brach, R. Mertelsmann, and F. Herrmann, Granulocytemacrophage colony-stimulating factor and interleukin-3 induce surface expression of interleukin-2 receptor p55-chain and CD4 by human eosinophils, Immunology, vol.70, pp.258-261, 1990.

S. Lajoie-kadoch, P. Joubert, S. Letuve, A. Halayko, J. Martin et al., TNF-?? and IFN-?? inversely modulate expression of the IL-17E receptor in airway smooth muscle cells, AJP: Lung Cellular and Molecular Physiology, vol.290, issue.6, pp.1238-1246, 2006.
DOI : 10.1152/ajplung.00301.2005

S. Letuve, S. Lajoie-kadoch, S. Audusseau, M. Rothenberg, P. Fiset et al., IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts, Journal of Allergy and Clinical Immunology, vol.117, issue.3, pp.590-596, 2006.
DOI : 10.1016/j.jaci.2005.10.025

C. Kuhn, R. Homer, Z. Zhu, N. Ward, R. Flavell et al., Airway Hyperresponsiveness and Airway Obstruction in Transgenic Mice, American Journal of Respiratory Cell and Molecular Biology, vol.22, issue.3, pp.289-295, 2000.
DOI : 10.1165/ajrcmb.22.3.3690

S. Molet, Q. Hamid, F. Davoine, E. Nutku, R. Taha et al., IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines, Journal of Allergy and Clinical Immunology, vol.108, issue.3, pp.430-438, 2001.
DOI : 10.1067/mai.2001.117929

T. Hansel, D. Vries, I. Iff, T. Rihs, S. Wandzilak et al., An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils, Journal of Immunological Methods, vol.145, issue.1-2, pp.105-110, 1991.
DOI : 10.1016/0022-1759(91)90315-7

S. Okada, J. Hagan, M. Kato, J. Bankers-fulbright, L. Hunt et al., Lidocaine and its analogues inhibit IL-5-mediated survival and activation of human eosinophils, J Immunol, vol.160, pp.4010-4017, 1998.

K. Livak and T. Schmittgen, Analysis of relative gene expression data using real-time quantitative PCR and the 2(?Delta Delta C(T)) Method, pp.402-408, 2001.

C. Herrick and K. Bottomly, To respond or not to respond: T cells in allergic asthma, Nature Reviews Immunology, vol.3, issue.5, pp.405-412, 2003.
DOI : 10.1038/nri1084

W. Al-ramli, D. Prefontaine, F. Chouiali, J. Martin, R. Olivenstein et al., TH17-associated cytokines (IL-17A and IL-17F) in severe asthma, Journal of Allergy and Clinical Immunology, vol.123, issue.5, pp.1185-1187, 2009.
DOI : 10.1016/j.jaci.2009.02.024

E. Truyen, L. Coteur, E. Dilissen, L. Overbergh, L. Dupont et al., Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patients, Thorax, vol.61, issue.3, pp.202-208, 2006.
DOI : 10.1136/thx.2005.052399

R. Halwani, S. Al-muhsen, H. Jahdali, and Q. Hamid, Role of Transforming Growth Factor????? in Airway Remodeling in Asthma, American Journal of Respiratory Cell and Molecular Biology, vol.44, issue.2, pp.127-133, 2011.
DOI : 10.1165/rcmb.2010-0027TR

H. Qin, L. Wang, T. Feng, C. Elson, S. Niyongere et al., TGF-?? Promotes Th17 Cell Development through Inhibition of SOCS3, The Journal of Immunology, vol.183, issue.1, pp.97-105, 2009.
DOI : 10.4049/jimmunol.0801986

N. Morishima, I. Mizoguchi, K. Takeda, J. Mizuguchi, and T. Yoshimoto, TGF-?? is necessary for induction of IL-23R and Th17 differentiation by IL-6 and IL-23, Biochemical and Biophysical Research Communications, vol.386, issue.1, pp.105-110, 2009.
DOI : 10.1016/j.bbrc.2009.05.140

L. Yang, D. Anderson, C. Baecher-allan, W. Hastings, E. Bettelli et al., IL-21 and TGF-?? are required for differentiation of human TH17 cells, Nature, vol.282, issue.7202, pp.350-352, 2008.
DOI : 10.1038/nature07021

T. Starnes, M. Robertson, G. Sledge, S. Kelich, H. Nakshatri et al., Cutting Edge: IL-17F, a Novel Cytokine Selectively Expressed in Activated T Cells and Monocytes, Regulates Angiogenesis and Endothelial Cell Cytokine Production, The Journal of Immunology, vol.167, issue.8, pp.4137-4140, 2001.
DOI : 10.4049/jimmunol.167.8.4137

L. Roussel, F. Houle, C. Chan, Y. Yao, J. Berube et al., IL-17 Promotes p38 MAPK-Dependent Endothelial Activation Enhancing Neutrophil Recruitment to Sites of Inflammation, The Journal of Immunology, vol.184, issue.8, pp.4531-4537, 2010.
DOI : 10.4049/jimmunol.0903162

A. Elovic, H. Ohyama, A. Sauty, J. Mcbride, T. Tsuji et al., IL-4-dependent regulation of TGF-alpha and TGF-beta1 expression in human eosinophils, J Immunol, vol.160, pp.6121-6127, 1998.

F. Wen, X. Liu, T. Kobayashi, S. Abe, Q. Fang et al., Interferon-?? Inhibits Transforming Growth Factor-?? Production in Human Airway Epithelial Cells by Targeting Smads, American Journal of Respiratory Cell and Molecular Biology, vol.30, issue.6, pp.816-822, 2004.
DOI : 10.1165/rcmb.2002-0249OC

Z. Shen, S. Esnault, L. Rosenthal, R. Szakaly, R. Sorkness et al., Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis, J Clin Invest, vol.118, pp.479-490, 2008.

J. Tsai, M. Kao, and S. Han, The Respiratory Burst Activity of Activated Eosinophils in Atopic Asthmatics, International Archives of Allergy and Immunology, vol.119, issue.1, pp.38-44, 1999.
DOI : 10.1159/000024173

S. Durham, D. Loegering, S. Dunnette, G. Gleich, and A. Kay, Blood eosinophils and eosinophil-derived proteins in allergic asthma, Journal of Allergy and Clinical Immunology, vol.84, issue.6, pp.931-936, 1989.
DOI : 10.1016/0091-6749(89)90391-6

P. Pignatti, L. Perfetti, E. Galdi, V. Pozzi, A. Bossi et al., Increased CD69 expression on peripheral blood eosinophils after specific inhalation challenge, Allergy, vol.179, issue.5, pp.411-416, 2002.
DOI : 10.1067/mai.2000.106924

G. Ciprandi, C. Cuppari, A. Salpietro, M. Tosca, L. Rigoli et al., Serum IL-23 strongly and inversely correlates with FEV1 in asthmatic children, Int Arch Allergy Immunol, vol.159, pp.183-186, 2012.

G. Ciprandi, C. Cuppari, and C. Salpietro, Serum IL-23: a surrogate biomarker for asthma?, Clinical & Experimental Allergy, vol.126, issue.9, pp.1416-1417, 1418.
DOI : 10.1111/j.1365-2222.2012.04068.x

R. Halwani, S. Al-muhsen, and Q. Hamid, T Helper 17 Cells in Airway Diseases, Chest, vol.143, issue.2, pp.494-501, 2013.
DOI : 10.1378/chest.12-0598

S. Gaffen, Structure and signalling in the IL-17 receptor family, Nature Reviews Immunology, vol.452, issue.8, pp.556-567, 2009.
DOI : 10.1038/nri2586

M. Rahman, A. Yamasaki, J. Yang, L. Shan, A. Halayko et al., IL-17A induces eotaxin-1/CC chemokine ligand 11 expression in human airway http://respiratory-research.com/content, 34 smooth muscle cells: role of MAPK (Erk1/2, JNK, and p38) pathways

Y. Xiao, C. Freire-de-lima, W. Schiemann, D. Bratton, R. Vandivier et al., Transcriptional and Translational Regulation of TGF-?? Production in Response to Apoptotic Cells, The Journal of Immunology, vol.181, issue.5, pp.3575-3585, 2008.
DOI : 10.4049/jimmunol.181.5.3575

P. Barnes and I. Adcock, Glucocorticoid resistance in inflammatory diseases, The Lancet, vol.373, issue.9678, pp.1905-1917, 2009.
DOI : 10.1016/S0140-6736(09)60326-3

A. Cuenda and S. Rousseau, p38 MAP-Kinases pathway regulation, function and role in human diseases, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1773, issue.8, pp.381358-1375, 2007.
DOI : 10.1016/j.bbamcr.2007.03.010