B. Pron, with the Components of the Blood???Brain Barrier Correlates with an Increased Expression of PilC, The Journal of Infectious Diseases, vol.176, issue.5, p.1285, 1997.
DOI : 10.1086/514124

M. Virji, The role of pili in the interactions of pathogenic Neisseria with cultured human endothelial cells, Molecular Microbiology, vol.135, issue.8, p.1831, 1991.
DOI : 10.1016/0882-4010(91)90057-H

A. J. Merz, C. A. Enns, and M. So, Type IV pili of pathogenic Neisseriae elicit cortical plaque formation in epithelial cells, Molecular Microbiology, vol.35, issue.6, p.1316, 1999.
DOI : 10.1016/S0955-0674(97)80155-X

G. Mikaty, Extracellular Bacterial Pathogen Induces Host Cell Surface Reorganization to Resist Shear Stress, PLoS Pathogens, vol.65, issue.18, p.1000314, 2009.
DOI : 10.1371/journal.ppat.1000314.s003

T. W. Hurd, L. Gao, M. H. Roh, I. G. Macara, and B. Margolis, Direct interaction of two polarity complexes implicated in epithelial tight junction assembly, Nature Cell Biology, vol.5, issue.2, p.137, 2003.
DOI : 10.1038/ncb923

W. Koh, R. D. Mahan, and G. E. Davis, Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling, Journal of Cell Science, vol.121, issue.7, p.989, 2008.
DOI : 10.1242/jcs.020693
URL : http://jcs.biologists.org/cgi/content/short/jcs.020693v1

T. Ooshio, Cooperative roles of Par-3 and afadin in the formation of adherens and tight junctions, Journal of Cell Science, vol.120, issue.14, p.2352, 2007.
DOI : 10.1242/jcs.03470

V. L. Madgula, B. Avula, V. L. Reddy, I. A. Khan, and S. I. Khan, Models for Intestinal and Blood-Brain Barrier Permeability, Planta Medica, vol.73, issue.4, p.330, 2007.
DOI : 10.1055/s-2007-967137

T. M. The-authors, P. Drab, I. Martin, and N. Allemand, Simpson for reviewing the manuscript. The authors are grateful to M. Garfa-Traore and N. Goudin for technical support Mathieu Coureuil was funded by " la Fondation pour la Recherche Médicale, p.767121, 2012.