Comparison between two treatment planning systems for volumetric modulated arc therapy optimization for prostate cancer.

Caroline Lafond 1, * Frédéric Gassa 2 Christophe Odin 3 Gaël Dréan 4 Justine Even 5 Renaud De Crevoisier 1 Pascal Pommier 2 Jean-Pierre Manens 1 Marie-Claude Biston 2
* Auteur correspondant
1 Impact
Service de radiothérapie, LTSI - Laboratoire Traitement du Signal et de l'Image
3 Matière molle
IPR - Institut de Physique de Rennes
Résumé : PURPOSE: To investigate the performances of two commercial treatment planning systems (TPS) for Volumetric Modulated Arc Therapy (VMAT) optimization regarding prostate cancer. The TPS were compared in terms of dose distributions, treatment delivery parameters and quality control results. MATERIALS AND METHODS: For ten patients, two VMAT plans were generated: one with Monaco TPS (Elekta) and one with Pinnacle TPS (Philips Medical Systems). The total prescribed dose was 78 Gy delivered in one 360° arc with a Synergy(®) linear accelerator equipped with a MLCi2(®). RESULTS: VMAT with Monaco provided better homogeneity and conformity indexes but lower mean dose to PTVs than Pinnacle. For the bladder wall (p = 0.019), the femoral heads (p = 0.017), and healthy tissues (p = 0.005), significantly lower mean doses were found using Monaco. For the rectal wall, VMAT with Pinnacle provided a significantly (p = 0.047) lower mean dose, and lower dose into 50% of the volume (p = 0.047) compared to Monaco. Despite a greater number of monitor units (factor 1.5) for Monaco TPS, the total treatment time was equivalent to that of Pinnacle. The treatment delivery parameter analysis showed larger mean MLC area for Pinnacle and lower mean dose rate compared to Monaco. The quality control results gave a high passing rate (>97.4%) for the gamma index for both TPS but Monaco provided slightly better results. CONCLUSION: For prostate cancer patients, VMAT treatment plans obtained with Monaco and Pinnacle offered clinically acceptable dose distributions. Further investigations are in progress to confirm the performances of the two TPS for irradiating more complex volumes.
Type de document :
Article dans des revues
Physica Medica, Elsevier, 2012, 30 (1), pp.2-9. <10.1016/j.ejmp.2012.10.003>


http://www.hal.inserm.fr/inserm-00750958
Contributeur : Lafond Caroline <>
Soumis le : lundi 12 novembre 2012 - 17:00:51
Dernière modification le : lundi 12 novembre 2012 - 17:00:51

Fichier

Lafond_et_al_PhysicaMedica_Fin...
Fichiers produits par l'(les) auteur(s)

Identifiants

Collections

Citation

Caroline Lafond, Frédéric Gassa, Christophe Odin, Gaël Dréan, Justine Even, et al.. Comparison between two treatment planning systems for volumetric modulated arc therapy optimization for prostate cancer.. Physica Medica, Elsevier, 2012, 30 (1), pp.2-9. <10.1016/j.ejmp.2012.10.003>. <inserm-00750958>

Exporter

Partager

Métriques