Spread and evolution of Plasmodium falciparum drug resistance, Parasitology International, vol.58, issue.3, pp.201-209, 2009. ,
DOI : 10.1016/j.parint.2009.04.004
Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets, Science, vol.333, issue.6043, pp.724-729, 2011. ,
DOI : 10.1126/science.1205216
Phase I randomized dose-ascending placebo-controlled trials of ferroquine - a candidate anti-malarial drug - in adults with asymptomatic Plasmodium falciparum infection, Malaria Journal, vol.10, issue.1, p.53, 2011. ,
DOI : 10.1056/NEJM198801073180101
In situ nanochemical imaging of label-free drugs: a case study of antimalarials in Plasmodium falciparum-infected erythrocytes, Chem. Commun., vol.145, issue.6, pp.910-912, 2011. ,
DOI : 10.1039/C1CC16211J
URL : https://hal.archives-ouvertes.fr/hal-00652186
CHLOROQUINE RESISTANCE IN MALARIA: A DEFICIENCY OF CHLOROQUINE BINDING, Proceedings of the National Academy of Sciences, vol.64, issue.4, pp.1181-1187, 1969. ,
DOI : 10.1073/pnas.64.4.1181
PfCRT-Mediated Drug Transport in Malarial Parasites, Biochemistry, vol.50, issue.2, pp.163-171, 2011. ,
DOI : 10.1021/bi101638n
Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum, Biochemical Pharmacology, vol.35, issue.21, pp.3805-3812, 1986. ,
DOI : 10.1016/0006-2952(86)90668-4
Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance, Science, vol.238, issue.4831, pp.1283-1285, 1987. ,
DOI : 10.1126/science.3317830
Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum, Biochemical Pharmacology, vol.44, issue.7, pp.1317-1324, 1992. ,
DOI : 10.1016/0006-2952(92)90532-N
Chloroquine Resistance in Plasmodium falciparum Malaria Parasites Conferred by pfcrt Mutations, Science, vol.298, issue.5591, pp.210-213, 2002. ,
DOI : 10.1126/science.1074045
Is PfCRT a channel or a carrier? Two competing models explaining chloroquine resistance in Plasmodium falciparum, Trends in Parasitology, vol.23, issue.7, pp.332-341, 2007. ,
DOI : 10.1016/j.pt.2007.04.013
Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter, Science, vol.325, issue.5948, pp.1680-1682, 2009. ,
DOI : 10.1126/science.1175667
Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance, Molecular Cell, vol.6, issue.4, pp.861-871, 2000. ,
DOI : 10.1016/S1097-2765(05)00077-8
Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum, Molecular Pharmacology, vol.61, issue.1, pp.35-42, 2002. ,
DOI : 10.1124/mol.61.1.35
The Antimalarial Ferroquine: Role of the Metal and Intramolecular Hydrogen Bond in Activity and Resistance, ACS Chemical Biology, vol.6, issue.3, pp.275-287, 2011. ,
DOI : 10.1021/cb100322v
URL : https://hal.archives-ouvertes.fr/hal-00595416
Quinine and Chloroquine Differentially Perturb Heme Monomer???Dimer Equilibrium, Inorganic Chemistry, vol.47, issue.13, pp.6077-6081, 2008. ,
DOI : 10.1021/ic800440d
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584347
Biomedical applications of the ESRF synchrotron-based microspectroscopy platform, Journal of Structural Biology, vol.177, issue.2, pp.248-258, 2012. ,
DOI : 10.1016/j.jsb.2011.12.006
URL : https://hal.archives-ouvertes.fr/inserm-00855368
In Vitro Activity of Ferroquine Is Independent of Polymorphisms in Transport Protein Genes Implicated in Quinoline Resistance in Plasmodium falciparum, Antimicrobial Agents and Chemotherapy, vol.52, issue.8, pp.2755-2759, 2008. ,
DOI : 10.1128/AAC.00060-08
Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action, Biochemical Pharmacology, vol.56, issue.10, pp.1305-1313, 1998. ,
DOI : 10.1016/S0006-2952(98)00184-1
Glutathione, Annual Review of Biochemistry, vol.52, issue.1, pp.711-760, 1983. ,
DOI : 10.1146/annurev.bi.52.070183.003431
Compartmentation of Redox Metabolism in Malaria Parasites, PLoS Pathogens, vol.3, issue.12, p.1001242, 2010. ,
DOI : 10.1371/journal.ppat.1001242.s009
Dissecting the role of glutathione biosynthesis in Plasmodium falciparum, Molecular Microbiology, vol.420, issue.2, pp.304-318, 2012. ,
DOI : 10.1111/j.1365-2958.2011.07933.x
Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics. Cellular and Molecular Life Sciences: CMLS. Available at, 2012. ,
Intracellular synchrotron nanoimaging and DNA damage/genotoxicity screening of novel lanthanide-coated nanovectors, Nanomedicine, vol.5, issue.10, pp.1547-1557, 2010. ,
DOI : 10.2217/nnm.10.96
URL : https://hal.archives-ouvertes.fr/inserm-00589259
Intracellular synchrotron nanoimaging and DNA damage/genotoxicity screening of novel lanthanide-coated nanovectors, Nanomedicine, vol.5, issue.10, pp.1547-1557, 2010. ,
DOI : 10.2217/nnm.10.96
URL : https://hal.archives-ouvertes.fr/inserm-00589259
A multiplatform code for the analysis of energy-dispersive X-ray fluorescence spectra, Spectrochimica Acta Part B: Atomic Spectroscopy, vol.62, issue.1, pp.63-68, 2007. ,
DOI : 10.1016/j.sab.2006.12.002