Dual Role for Argonautes in MicroRNA Processing and Posttranscriptional Regulation of MicroRNA Expression, Cell, vol.131, issue.6, pp.1097-1108, 2007. ,
DOI : 10.1016/j.cell.2007.10.032
Crystal Structure of A. aeolicus Argonaute, a Site-Specific DNA-Guided Endoribonuclease, Provides Insights into RISC-Mediated mRNA Cleavage, Molecular Cell, vol.19, issue.3, pp.405-419, 2005. ,
DOI : 10.1016/j.molcel.2005.07.011
Nucleic acid 3???-end recognition by the Argonaute2 PAZ domain, Nature Structural & Molecular Biology, vol.11, issue.6, pp.576-577, 2004. ,
DOI : 10.1038/nsb1016
Crystal structure and ligand binding of the MID domain of a eukaryotic Argonaute protein, EMBO reports, vol.364, issue.7 ,
DOI : 10.1016/j.molcel.2005.07.011
Allosteric regulation of Argonaute proteins by miRNAs, Nature Structural & Molecular Biology, vol.543, issue.2, pp.144-150, 2010. ,
DOI : 10.1093/emboj/18.19.5175
Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity, Science, vol.305, issue.5689, pp.1434-1437, 2004. ,
DOI : 10.1126/science.1102514
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways, Genes & Development, vol.18, issue.14, pp.1655-1666, 2004. ,
DOI : 10.1101/gad.1210204
Argonaute2 Is the Catalytic Engine of Mammalian RNAi, Science, vol.305, issue.5689, pp.1437-1441, 2004. ,
DOI : 10.1126/science.1102513
Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs, Molecular Cell, vol.15, issue.2, pp.185-197, 2004. ,
DOI : 10.1016/j.molcel.2004.07.007
URL : http://doi.org/10.1016/j.molcel.2004.07.007
Prediction of Plant MicroRNA Targets, Cell, vol.110, issue.4, pp.513-520, 2002. ,
DOI : 10.1016/S0092-8674(02)00863-2
MicroRNAs AND THEIR REGULATORY ROLES IN PLANTS, Annual Review of Plant Biology, vol.57, issue.1, pp.19-53, 2006. ,
DOI : 10.1146/annurev.arplant.57.032905.105218
Prediction of Mammalian MicroRNA Targets, Cell, vol.115, issue.7, pp.787-798, 2003. ,
DOI : 10.1016/S0092-8674(03)01018-3
Specificity of microRNA target selection in translational repression, Genes & Development, vol.18, issue.5, pp.504-511, 2004. ,
DOI : 10.1101/gad.1184404
Principles of MicroRNA???Target Recognition, PLoS Biology, vol.5, issue.3, pp.85-85, 2005. ,
DOI : 10.1371/journal.pbio.0030085.g007
Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets, Cell, vol.120, issue.1, pp.15-20, 2005. ,
DOI : 10.1016/j.cell.2004.12.035
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate, The EMBO Journal, vol.20, issue.23, pp.6877-88, 2001. ,
DOI : 10.1093/emboj/20.23.6877
MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing, Molecular Cell, vol.27, issue.1, pp.91-105, 2007. ,
DOI : 10.1016/j.molcel.2007.06.017
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?, Nature Reviews Genetics, vol.131, issue.2, pp.102-114, 2008. ,
DOI : 10.1038/nrg2290
The code within the code: microRNAs target coding regions, Cell Cycle, vol.9, issue.8, pp.1533-1574, 2010. ,
DOI : 10.4161/cc.9.8.11202
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR, Proceedings of the National Academy of Sciences, vol.104, issue.23, pp.9667-72, 2007. ,
DOI : 10.1073/pnas.0703820104
MicroRNAs: Target Recognition and Regulatory Functions, Cell, vol.136, issue.2, pp.215-233, 2009. ,
DOI : 10.1016/j.cell.2009.01.002
URL : http://doi.org/10.1016/j.cell.2009.01.002
Most mammalian mRNAs are conserved targets of microRNAs Combinatorial microRNA target predictions, Genome Res . Nat Genet, vol.19, issue.37, pp.92-105, 2005. ,
Human MicroRNA Targets, PLoS Biology, vol.31, issue.11, pp.363-363, 2004. ,
DOI : 10.1371/journal.pbio.0020363.st013
URL : http://doi.org/10.1371/journal.pbio.0020363
The microRNA.org resource: targets and expression, Nucleic Acids Research, vol.36, issue.Database, pp.149-153, 2008. ,
DOI : 10.1093/nar/gkm995
The role of site accessibility in microRNA target recognition, Nature Genetics, vol.26, issue.10, pp.1278-1284, 2007. ,
DOI : 10.1038/ng2135
Inference of miRNA targets using evolutionary conservation and pathway analysis, BMC Bioinformatics, vol.8, issue.1, pp.69-69, 2007. ,
DOI : 10.1186/1471-2105-8-69
A combined computational-experimental approach predicts human microRNA targets, Genes & Development, vol.18, issue.10, pp.1165-1178, 2004. ,
DOI : 10.1101/gad.1184704
A guide through present computational approaches for the identification of mammalian microRNA targets, Nature Methods, vol.11, issue.11, pp.881-886, 2006. ,
DOI : 10.1038/nmeth954
A MicroRNA Screen to Identify Modulators of Sensitivity to BCL2 Inhibitor ABT-263 (Navitoclax), Molecular Cancer Therapeutics, vol.9, issue.11, pp.2943-50, 2010. ,
DOI : 10.1158/1535-7163.MCT-10-0427
TarBase: A comprehensive database of experimentally supported animal microRNA targets, RNA, vol.12, issue.2, pp.192-197, 2006. ,
DOI : 10.1261/rna.2239606
The database of experimentally supported targets: a functional update of TarBase, Nucleic Acids Research, vol.37, issue.Database, pp.155-158, 2009. ,
DOI : 10.1093/nar/gkn809
Molecular mechanisms of translation initiation in eukaryotes, Proceedings of the National Academy of Sciences, vol.98, issue.13, pp.7029-7036, 2001. ,
DOI : 10.1073/pnas.111145798
Molecular mechanisms of translational control, Nature Reviews Molecular Cell Biology, vol.19, issue.10, pp.827-835, 2004. ,
DOI : 10.1126/SCIENCE.1064023
The role of mRNA 5???-noncoding and 3???-end sequences on 40S ribosomal subunit recruitment, and how RNA viruses successfully compete with cellular mRNAs to ensure their own protein synthesis, Biology of the Cell, vol.95, issue.3-4, pp.129-139, 2003. ,
DOI : 10.1016/S0248-4900(03)00030-3
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function, Proceedings of the National Academy of Sciences, vol.102, issue.47, pp.16961-16966, 2005. ,
DOI : 10.1073/pnas.0506482102
Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells, Science, vol.309, issue.5740, pp.1573-1576, 2005. ,
DOI : 10.1126/science.1115079
An mRNA m7G Cap Binding-like Motif within Human Ago2 Represses Translation, Cell, vol.129, issue.6, pp.1141-1151, 2007. ,
DOI : 10.1016/j.cell.2007.05.016
MicroRNA silencing through RISC recruitment of eIF6, Nature, vol.23, issue.7146 ,
DOI : 10.1038/nature05841
The lin-4 Regulatory RNA Controls Developmental Timing in Caenorhabditis elegans by Blocking LIN-14 Protein Synthesis after the Initiation of Translation, Developmental Biology, vol.216, issue.2, pp.671-680, 1999. ,
DOI : 10.1006/dbio.1999.9523
Two Genetic Circuits Repress the Caenorhabditis elegans Heterochronic Gene lin-28 after Translation Initiation, Developmental Biology, vol.243, issue.2, pp.215-225, 2002. ,
DOI : 10.1006/dbio.2001.0563
Short RNAs Repress Translation after Initiation in Mammalian Cells, Molecular Cell, vol.21, issue.4, pp.533-542, 2006. ,
DOI : 10.1016/j.molcel.2006.01.031
Evidence that microRNAs are associated with translating messenger RNAs in human cells, Nature Structural & Molecular Biology, vol.4, issue.12, pp.1102-1107, 2006. ,
DOI : 10.1038/nsmb1174
Human let-7a miRNA blocks protein production on actively translating polyribosomes, Nature Structural & Molecular Biology, vol.285, issue.12, pp.1108-1114, 2006. ,
DOI : 10.1038/nsmb1173
Regulation by let-7 and lin-4 miRNAs Results in Target mRNA Degradation, Cell, vol.122, issue.4, pp.553-563, 2005. ,
DOI : 10.1016/j.cell.2005.07.031
Micro-RNA Regulation of the Mammalian lin-28 Gene during Neuronal Differentiation of Embryonal Carcinoma Cells, Molecular and Cellular Biology, vol.25, issue.21, pp.9198-9208, 2005. ,
DOI : 10.1128/MCB.25.21.9198-9208.2005
MicroRNAs direct rapid deadenylation of mRNA, Proceedings of the National Academy of Sciences, vol.103, issue.11, pp.4034-4039, 2006. ,
DOI : 10.1073/pnas.0510928103
The enzymes and control of eukaryotic mRNA turnover, Nature Structural & Molecular Biology, vol.11, issue.2, pp.121-127, 2004. ,
DOI : 10.1038/nsmb724
P bodies: at the crossroads of post-transcriptional pathways, Nature Reviews Molecular Cell Biology, vol.89, issue.1, pp.9-22, 2007. ,
DOI : 10.1038/nrm2080
The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci, RNA, vol.8, pp.1489-1501, 2002. ,
Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies, Science, vol.300, issue.5620, pp.805-808, 2003. ,
DOI : 10.1126/science.1082320
Movement of Eukaryotic mRNAs Between Polysomes and Cytoplasmic Processing Bodies, Science, vol.310, issue.5747, pp.486-489, 2005. ,
DOI : 10.1126/science.1115791
A Phosphorylated Cytoplasmic Autoantigen, GW182, Associates with a Unique Population of Human mRNAs within Novel Cytoplasmic Speckles, Molecular Biology of the Cell, vol.13, issue.4, pp.1338-1351, 2002. ,
DOI : 10.1091/mbc.01-11-0544
A role for the P-body component GW182 in microRNA function, Nature Cell Biology, vol.128, issue.12, pp.1261-1266, 2005. ,
DOI : 10.1016/S1534-5807(03)00400-3
Stress granules: sites of mRNA triage that regulate mRNA stability and translatability, Biochemical Society Transactions, vol.30, issue.6, pp.963-969, 2002. ,
DOI : 10.1042/bst0300963
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling, The Journal of Cell Biology, vol.20, issue.6, pp.871-884, 2005. ,
DOI : 10.1242/jcs.01477
AU-Rich-Element-Mediated Upregulation of Translation by FXR1 and Argonaute 2, Cell, vol.128, issue.6, pp.1105-1118, 2007. ,
DOI : 10.1016/j.cell.2007.01.038
miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts, Cell, vol.140, issue.5, pp.652-65, 2010. ,
DOI : 10.1016/j.cell.2010.01.007
bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila, Cell, vol.113, issue.1, pp.25-36, 2003. ,
DOI : 10.1016/S0092-8674(03)00231-9
MicroRNAs Modulate Hematopoietic Lineage Differentiation, Science, vol.303, issue.5654, pp.83-86, 2004. ,
DOI : 10.1126/science.1091903
MicroRNAs in vertebrate development, Current Opinion in Genetics & Development, vol.15, issue.4, pp.410-415, 2005. ,
DOI : 10.1016/j.gde.2005.06.012
MicroRNAs: a developing story, Current Opinion in Genetics & Development, vol.15, issue.2, pp.200-205, 2005. ,
DOI : 10.1016/j.gde.2005.01.002
MicroRNA expression profiles classify human cancers, Nature, vol.1, issue.7043, pp.834-838, 2005. ,
DOI : 10.1016/S1535-6108(02)00018-1
A microRNA expression signature of human solid tumors defines cancer gene targets, Proceedings of the National Academy of Sciences, vol.103, issue.7, pp.2257-61, 2006. ,
DOI : 10.1073/pnas.0510565103
MicroRNA and cancer - focus on apoptosis, Journal of Cellular and Molecular Medicine, vol.107, issue.Suppl, pp.12-23, 2009. ,
DOI : 10.1111/j.1582-4934.2008.00510.x
MicroRNA and Target Protein Patterns Reveal Physiopathological Features of Glioma Subtypes, PLoS ONE, vol.30, issue.9, pp.20600-2011 ,
DOI : 10.1371/journal.pone.0020600.s009
URL : https://hal.archives-ouvertes.fr/inserm-00734099
Expression Profiling of Difficult-to-diagnose Thyroid Histologic Subtypes Shows Distinct Expression Profiles and Identify Candidate Diagnostic microRNAs, Annals of Surgical Oncology, vol.111, issue.7175, pp.3443-52, 2011. ,
DOI : 10.1245/s10434-011-1766-4
Accurate Molecular Classification of Kidney Cancer Subtypes Using MicroRNA Signature, European Urology, vol.59, issue.5, pp.721-751, 2011. ,
DOI : 10.1016/j.eururo.2011.01.004
Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer, Dicer, Drosha, and outcomes in patients with ovarian cancer, pp.2641-2650, 2008. ,
DOI : 10.1056/NEJMoa0803785
Expression Levels of the microRNA Processing Enzymes Drosha and Dicer in Epithelial Skin Cancer, Cancer Investigation, vol.6, issue.6, pp.649-653, 2010. ,
DOI : 10.1111/j.1349-7006.2005.00015.x
RNASEN Regulates Cell Proliferation and Affects Survival in Esophageal Cancer Patients, Clinical Cancer Research, vol.12, issue.24, pp.7322-7328, 2006. ,
DOI : 10.1158/1078-0432.CCR-06-0515
Up-Regulation of Dicer, a Component of the MicroRNA Machinery, in Prostate Adenocarcinoma, The American Journal of Pathology, vol.169, issue.5, pp.1812-1820, 2006. ,
DOI : 10.2353/ajpath.2006.060480
Overexpression of Dicer in Precursor Lesions of Lung Adenocarcinoma, Cancer Research, vol.67, issue.5, pp.2345-2350, 2007. ,
DOI : 10.1158/0008-5472.CAN-06-3533
Reduced expression of Dicer associated with poor prognosis in lung cancer patients, Cancer Science, vol.10, issue.2, pp.111-115, 2005. ,
DOI : 10.1038/ng0494-332
A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function, Nature Genetics, vol.59, issue.3, pp.365-70, 2009. ,
DOI : 10.1073/pnas.0511155103
The Tumor Suppressors p53, p63, and p73 Are Regulators of MicroRNA Processing Complex, PLoS ONE, vol.14, issue.7, pp.10615-10615, 2010. ,
DOI : 10.1371/journal.pone.0010615.s003
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers, Proceedings of the National Academy of Sciences, vol.101, issue.9, pp.2999-3004, 2004. ,
DOI : 10.1073/pnas.0307323101
MicroRNAs: A New Insight into Cancer Genome, Cell Cycle, vol.5, issue.19, pp.2216-2219, 2006. ,
DOI : 10.4161/cc.5.19.3319
Myeloid cell differentiation arrest by miR-125b-1 in myelodysplasic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation, The Journal of Experimental Medicine, vol.55, issue.11, pp.2499-2506, 2008. ,
DOI : 10.1084/jem.178.6.1995
PPM1D is a potential target for 17q gain in neuroblastoma, Cancer Res, vol.63, pp.1876-1883, 2003. ,
Human polymorphism at microRNAs and microRNA target sites, Proceedings of the National Academy of Sciences, vol.104, issue.9, pp.3300-3305, 2007. ,
DOI : 10.1073/pnas.0611347104
Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma, Proceedings of the National Academy of Sciences, vol.105, issue.20, pp.7269-7274, 2008. ,
DOI : 10.1073/pnas.0802682105
A functional polymorphism in Pre-miR-146a gene is associated with prostate cancer risk and mature miR-146a expression in vivo, Prostate, vol.70, pp.467-472, 2010. ,
Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA, Human Molecular Genetics, vol.16, issue.9, pp.1124-1131, 2007. ,
DOI : 10.1093/hmg/ddm062
Germline mutation of microRNA-125a is associated with breast cancer, Journal of Medical Genetics, vol.46, issue.5, pp.358-360, 2009. ,
DOI : 10.1136/jmg.2008.063123
Genetic variants of miRNA sequences and non???small cell lung cancer survival, Journal of Clinical Investigation, vol.118, pp.2600-2608, 2008. ,
DOI : 10.1172/JCI34934
A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia, New England Journal of Medicine, vol.353, issue.17, pp.1793-801, 2005. ,
DOI : 10.1056/NEJMoa050995
A novel mutation in the miR-128b gene reduces miRNA processing and leads to glucocorticoid resistance of MLL-AF4 Acute Lymphocytic Leukemia cells, Cell Cycle, vol.9, issue.6, pp.1037-1079, 2010. ,
DOI : 10.4161/cc.9.6.11011
Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification, RNA, vol.10, issue.9 ,
DOI : 10.1261/rna.5206304
Differentially Regulated Micro-RNAs and Actively Translated Messenger RNA Transcripts by Tumor Suppressor p53 in Colon Cancer, Clinical Cancer Research, vol.12, issue.7, pp.2014-2024, 2006. ,
DOI : 10.1158/1078-0432.CCR-05-1853
Transactivation of miR-34a by p53 Broadly??Influences Gene Expression and??Promotes??Apoptosis, Molecular Cell, vol.26, issue.5, pp.745-752, 2007. ,
DOI : 10.1016/j.molcel.2007.05.010
Transcriptional Activation of miR-34a Contributes to p53-Mediated Apoptosis, Molecular Cell, vol.26, issue.5, pp.731-743, 2007. ,
DOI : 10.1016/j.molcel.2007.05.017
Differential Regulation of microRNAs by p53 Revealed by Massively Parallel Sequencing: miR-34a is a p53 Target That Induces Apoptosis and G1-arrest, Cell Cycle, vol.6, issue.13, pp.1586-1593, 2007. ,
DOI : 10.4161/cc.6.13.4436
p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation, Molecular Systems Biology, vol.19, pp.229-229, 2008. ,
DOI : 10.1016/j.ccr.2006.01.025
Multiple E2F-Induced MicroRNAs Prevent Replicative Stress in Response to Mitogenic Signaling, Molecular and Cellular Biology, vol.30, issue.12, pp.2983-2995, 2005. ,
DOI : 10.1128/MCB.01372-09
Widespread microRNA repression by Myc contributes to tumorigenesis, Nature Genetics, vol.121, issue.1, pp.43-50, 2008. ,
DOI : 10.1038/ng.2007.30
Effects of DNA methylation on DNA-binding proteins and gene expression, Current Opinion in Genetics & Development, vol.3, issue.2, pp.226-231, 1993. ,
DOI : 10.1016/0959-437X(93)90027-M
Epigenetic Activation of Tumor Suppressor MicroRNAs in Human Cancer Cells, Cell Cycle, vol.5, issue.19, pp.2220-2222, 2006. ,
DOI : 10.4161/cc.5.19.3340
Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells, Cancer Cell, vol.9, issue.6, pp.435-443, 2006. ,
DOI : 10.1016/j.ccr.2006.04.020
Genetic Unmasking of an Epigenetically Silenced microRNA in Human Cancer Cells, Cancer Research, vol.67, issue.4, pp.1424-1429, 2007. ,
DOI : 10.1158/0008-5472.CAN-06-4218
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer . Cell Cycle, pp.2591-2600, 2008. ,
The Human let-7a-3 Locus Contains an Epigenetically Regulated MicroRNA Gene with Oncogenic Function, Cancer Research, vol.67, issue.4, pp.1419-1423, 2007. ,
DOI : 10.1158/0008-5472.CAN-06-4074
An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1?? 3' untranslated region confers risk for hepatocellular carcinoma, Carcinogenesis, vol.30, issue.12, pp.2064-2069, 2009. ,
DOI : 10.1093/carcin/bgp283
Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival, Blood, vol.109, issue.11, pp.4599-4606, 2007. ,
DOI : 10.1182/blood-2006-08-039859
Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma, Blood, vol.112, issue.3, pp.822-829, 2008. ,
DOI : 10.1182/blood-2008-03-142182
Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation, Science, vol.315, issue.5818, pp.1576-1579, 2007. ,
DOI : 10.1126/science.1137999
Increased expression of high mobility group A proteins in lung cancer, The Journal of Pathology, vol.91, issue.2, pp.206-212, 2006. ,
DOI : 10.1002/path.1960
HMGA2 overexpression in non-small cell lung cancer, Molecular Carcinogenesis, vol.88, issue.7, pp.503-511, 2007. ,
DOI : 10.1002/mc.20235
HMGA2 Participates in Transformation in Human Lung Cancer, Molecular Cancer Research, vol.6, issue.5, pp.743-750, 2008. ,
DOI : 10.1158/1541-7786.MCR-07-0095
An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue, British Journal of Cancer, vol.89, issue.11, pp.2104-2109, 2003. ,
DOI : 10.1038/sj.bjc.6601391
Regulation of ABCG2 Expression at the 3' Untranslated Region of Its mRNA through Modulation of Transcript Stability and Protein Translation by a Putative MicroRNA in the S1 Colon Cancer Cell Line, Molecular and Cellular Biology, vol.28, issue.17, pp.5147-61, 2008. ,
DOI : 10.1128/MCB.00331-08
Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers, Nucleic Acids Research, vol.35, issue.13, pp.4535-4541, 2007. ,
DOI : 10.1093/nar/gkm480
The role of microRNA genes in papillary thyroid carcinoma, Proceedings of the National Academy of Sciences, vol.102, issue.52, pp.19075-19080, 2005. ,
DOI : 10.1073/pnas.0509603102
Polymorphisms within micro-RNA-binding sites and risk of sporadic colorectal cancer, Carcinogenesis, vol.29, issue.3, pp.579-584, 2008. ,
DOI : 10.1093/carcin/bgm304
A SNP in a let-7 microRNA Complementary Site in the KRAS 3' Untranslated Region Increases Non-Small Cell Lung Cancer Risk, Cancer Research, vol.68, issue.20, pp.8535-8540, 2008. ,
DOI : 10.1158/0008-5472.CAN-08-2129
A 3???-untranslated region KRAS variant and triple-negative breast cancer: a case-control and genetic analysis, The Lancet Oncology, vol.12, issue.4, pp.377-86, 2011. ,
DOI : 10.1016/S1470-2045(11)70044-4
Polymorphisms in predicted microRNA-binding sites in integrin genes and breast cancer: ITGB4 as prognostic marker, Carcinogenesis, vol.29, issue.7, pp.1394-1399, 2008. ,
DOI : 10.1093/carcin/bgn126
A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors, Cell, vol.124, issue.6, pp.1169-1181, 2006. ,
DOI : 10.1016/j.cell.2006.02.037
A Polycistronic MicroRNA Cluster, miR-17-92, Is Overexpressed in Human Lung Cancers and Enhances Cell Proliferation, Cancer Research, vol.65, issue.21, pp.9628-9632, 2005. ,
DOI : 10.1158/0008-5472.CAN-05-2352
A microRNA polycistron as a potential human oncogene, Nature, vol.1, issue.7043, pp.828-833, 2005. ,
DOI : 10.1093/BIOINFORMATICS/16.11.1046
Avian bic, a Gene Isolated from a Common Retroviral Site in Avian Leukosis Virus-Induced Lymphomas That Encodes a Noncoding RNA, Cooperates with c-myc in Lymphomagenesis and Erythroleukemogenesis, Journal of Virology, vol.76, issue.9, pp.4275-4286, 2002. ,
DOI : 10.1128/JVI.76.9.4275-4286.2002
Accumulation of miR-155 and BIC RNA in human B cell lymphomas, Proceedings of the National Academy of Sciences, vol.102, issue.10, pp.3627-3632, 2005. ,
DOI : 10.1073/pnas.0500613102
BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas, The Journal of Pathology, vol.159, issue.2, pp.243-249, 2005. ,
DOI : 10.1002/path.1825
Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E??-miR155 transgenic mice, Proceedings of the National Academy of Sciences, vol.103, issue.18, pp.7024-7029, 2003. ,
DOI : 10.1073/pnas.0602266103
Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer, Cancer, vol.17, issue.8, pp.1697-1707, 2007. ,
DOI : 10.1002/cncr.22983
MicroRNA-21 Targets the Tumor Suppressor Gene Tropomyosin 1 (TPM1), Journal of Biological Chemistry, vol.282, issue.19, pp.14328-14336, 2007. ,
DOI : 10.1074/jbc.M611393200
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer, Oncogene, vol.62, issue.15, pp.2128-2136, 2008. ,
DOI : 10.1074/jbc.M611393200
MicroRNA Gene Expression Deregulation in Human Breast Cancer, Cancer Research, vol.65, issue.16, pp.7065-7070, 2005. ,
DOI : 10.1158/0008-5472.CAN-05-1783
RAS Is Regulated by the let-7 MicroRNA Family, Cell, vol.120, issue.5, pp.635-647, 2005. ,
DOI : 10.1016/j.cell.2005.01.014
let-7 MicroRNA Functions as a Potential Growth Suppressor in Human Colon Cancer Cells, Biological & Pharmaceutical Bulletin, vol.29, issue.5, pp.903-906, 2006. ,
DOI : 10.1248/bpb.29.903
The tumor suppressor microRNA let-7 represses the HMGA2 oncogene, Genes & Development, vol.21, issue.9, pp.1025-1030, 2007. ,
DOI : 10.1101/gad.1540407
MicroRNA Let-7a Down-regulates MYC and Reverts MYC-Induced Growth in Burkitt Lymphoma Cells, Cancer Research, vol.67, issue.20, pp.9762-9770, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-2462
Chromosomal deletions and tumor suppressor genes in prostate cancer, Cancer Metastasis Rev, vol.20, pp.173-193, 2001. ,
DOI : 10.1007/0-306-48143-X_4
MiR-15a and miR-16-1 cluster functions in human leukemia, Proceedings of the National Academy of Sciences, vol.105, issue.13, pp.5166-5171, 2008. ,
DOI : 10.1073/pnas.0800121105
Down-regulation of Micro-RNA-1 (miR-1) in Lung Cancer: SUPPRESSION OF TUMORIGENIC PROPERTY OF LUNG CANCER CELLS AND THEIR SENSITIZATION TO DOXORUBICIN-INDUCED APOPTOSIS BY miR-1, Journal of Biological Chemistry, vol.283, issue.48, pp.33394-33405, 2008. ,
DOI : 10.1074/jbc.M804788200
MicroRNA-7, a Homeobox D10 Target, Inhibits p21-Activated Kinase 1 and Regulates Its Functions, Cancer Research, vol.68, issue.20, pp.8195-8200, 2008. ,
DOI : 10.1158/0008-5472.CAN-08-2103
microRNA-34a is tumor suppressive in brain tumors and glioma stem cells, Cell Cycle, vol.9, issue.6 ,
DOI : 10.4161/cc.9.6.10987
A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene, Molecular Cancer Research, vol.6, issue.5, pp.735-777, 2008. ,
DOI : 10.1158/1541-7786.MCR-07-2102
miR2Disease: a manually curated database for microRNA deregulation in human disease, Nucleic Acids Research, vol.37, issue.Database, pp.98-104, 2009. ,
DOI : 10.1093/nar/gkn714
DEATH AND ANTI-DEATH: TUMOUR RESISTANCE TO APOPTOSIS, Nature Reviews Cancer, vol.2, issue.4, pp.277-288, 2002. ,
DOI : 10.1038/nrc776
The role of Bcl-2 family members in the progression of cutaneous melanoma, Clinical and Experimental Metastasis, vol.20, issue.6, pp.531-539, 2003. ,
DOI : 10.1023/A:1025874502181
The role of the Bcl-2 protein family in cancer, Seminars in Cancer Biology, vol.13, issue.2, pp.115-123, 2003. ,
DOI : 10.1016/S1044-579X(02)00129-3
Bcl-2 family proteins and mitochondria, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1366, issue.1-2, pp.127-137, 1998. ,
DOI : 10.1016/S0005-2728(98)00108-X
Role of mitochondrial membrane permeabilization in apoptosis and cancer, Oncogene, vol.23, issue.16, pp.2850-2860, 2004. ,
DOI : 10.1038/sj.onc.1207534
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade, Cell, vol.91, issue.4, pp.479-489, 1997. ,
DOI : 10.1016/S0092-8674(00)80434-1
Smac, a Mitochondrial Protein that Promotes Cytochrome c???Dependent Caspase Activation by Eliminating IAP Inhibition, Cell, vol.102, issue.1, pp.33-42, 2000. ,
DOI : 10.1016/S0092-8674(00)00008-8
Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins, Cell, vol.102, issue.1, pp.43-53, 2000. ,
DOI : 10.1016/S0092-8674(00)00009-X
FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis, Cell, vol.81, issue.4 ,
DOI : 10.1016/0092-8674(95)90071-3
Bid Induces the Oligomerization and Insertion of Bax into the Outer Mitochondrial Membrane, Molecular and Cellular Biology, vol.20, issue.3, pp.929-935, 2000. ,
DOI : 10.1128/MCB.20.3.929-935.2000
Apoptomirs: small molecules have gained the license to kill, Endocrine Related Cancer, vol.17, issue.1, pp.37-50, 2010. ,
DOI : 10.1677/ERC-09-0163
miR-15 and miR-16 induce apoptosis by targeting BCL2, Proceedings of the National Academy of Sciences, vol.102, issue.39, pp.13944-13949, 2005. ,
DOI : 10.1073/pnas.0506654102
Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17???92 Family of miRNA Clusters, Cell, vol.132, issue.5, pp.875-886, 2008. ,
DOI : 10.1016/j.cell.2008.02.019
Genomic Profiling of MicroRNA and Messenger RNA Reveals Deregulated MicroRNA Expression in Prostate Cancer, Cancer Research, vol.68, issue.15, pp.6162-6170, 2008. ,
DOI : 10.1158/0008-5472.CAN-08-0144
E2F1-Regulated MicroRNAs Impair TGF??-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer, Cancer Cell, vol.13, issue.3, pp.272-286, 2008. ,
DOI : 10.1016/j.ccr.2008.02.013
miR-34a repression of SIRT1 regulates apoptosis, Proceedings of the National Academy of Sciences, vol.105, issue.36, pp.13421-13426, 2008. ,
DOI : 10.1073/pnas.0801613105
MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma, Molecular Cancer, vol.9, issue.1, pp.229-229, 2010. ,
DOI : 10.1186/1476-4598-9-229
Regulation of the p27Kip1 tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation, The EMBO Journal, vol.103, issue.15, pp.3699-3708, 2007. ,
DOI : 10.1038/sj.emboj.7601790
The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes, Journal of Cell Science, vol.120, issue.17, pp.3045-3052, 2007. ,
DOI : 10.1242/jcs.010728
MicroRNA-21 Is an Antiapoptotic Factor in Human Glioblastoma Cells, Cancer Research, vol.65, issue.14, pp.6029-6033, 2005. ,
DOI : 10.1158/0008-5472.CAN-05-0137
MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells, Cancer Research, vol.68, issue.19, pp.8164-8172, 2008. ,
DOI : 10.1158/0008-5472.CAN-08-1305
siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21 ,
MicroRNA-21 Is a Downstream Effector of AKT That Mediates Its Antiapoptotic Effects via Suppression of Fas Ligand, Journal of Biological Chemistry, vol.285, issue.26, pp.20281-20290, 2010. ,
DOI : 10.1074/jbc.M110.109207
Genome-Scale MicroRNA and Small Interfering RNA Screens Identify Small RNA Modulators of TRAIL-Induced Apoptosis Pathway, Cancer Research, vol.67, issue.22, pp.10782-10788, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-1484
Principles and Therapeutic Implications of Angiogenesis, Vasculogenesis and Arteriogenesis, Handb Exp Pharmacol, pp.157-212, 2006. ,
DOI : 10.1007/3-540-36028-X_6
New molecular pathways in angiogenesis, British Journal of Cancer, vol.89, issue.2, pp.228-259, 2003. ,
DOI : 10.1038/sj.bjc.6601107
Role of Dicer and Drosha for Endothelial MicroRNA Expression and Angiogenesis, Circulation Research, vol.101, issue.1, pp.59-68, 2007. ,
DOI : 10.1161/CIRCRESAHA.107.153916
AngiomiRs???Key regulators of angiogenesis, Current Opinion in Genetics & Development, vol.19, issue.3, pp.205-211, 2009. ,
DOI : 10.1016/j.gde.2009.04.002
The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis, Developmental Cell, vol.15, issue.2, pp.261-271, 2008. ,
DOI : 10.1016/j.devcel.2008.07.002
miR-126 Regulates Angiogenic Signaling and Vascular Integrity, Developmental Cell, vol.15, issue.2, pp.272-84, 2008. ,
DOI : 10.1016/j.devcel.2008.07.008
EGFL7 meets miRNA-126: an angiogenesis alliance, Journal of Angiogenesis Research, vol.2, issue.1, pp.9-2010 ,
DOI : 10.1186/2040-2384-2-9
MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression, Proceedings of the National Academy of Sciences, vol.104, issue.51, pp.20350-20355, 2007. ,
DOI : 10.1073/pnas.0706901104
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster, Nature Genetics, vol.265, issue.9, pp.1060-1065, 2006. ,
DOI : 10.1056/NEJMoa032691
MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3, Journal of Biological Chemistry, vol.283, issue.23, pp.15878-15883, 2008. ,
DOI : 10.1074/jbc.M800731200
Regulation of angiogenesis through a microRNA (miR-130a) that down-regulates antiangiogenic homeobox genes GAX and HOXA5, Blood, vol.111, issue.3, pp.1217-1226, 2008. ,
DOI : 10.1182/blood-2007-07-104133
MicroRNAs modulate the angiogenic properties of HUVECs, Blood, vol.108, issue.9, pp.3068-3071, 2006. ,
DOI : 10.1182/blood-2006-01-012369
MiRNA-Directed Regulation of VEGF and Other Angiogenic Factors under Hypoxia, PLoS ONE, vol.32, issue.1, pp.116-116, 2006. ,
DOI : 10.1371/journal.pone.0000116.s002
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells, Nature Cell Biology, vol.175, issue.6, pp.654-663, 2007. ,
DOI : 10.1002/pmic.200400876
Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis, Cancer Science, vol.10, issue.10, pp.2087-2092, 2010. ,
DOI : 10.1111/j.1349-7006.2010.01650.x
Indirect activation of na??ve CD4+ T cells by dendritic cell???derived exosomes, Nature Immunology, vol.3, issue.12, pp.1156-62, 2002. ,
DOI : 10.1038/ni854
Exosomes: From biogenesis and secretion to biological function, Immunology Letters, vol.107, issue.2, pp.102-108, 2006. ,
DOI : 10.1016/j.imlet.2006.09.005
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers, Nature Cell Biology, vol.94, issue.12, pp.1470-1476, 2008. ,
DOI : 10.1371/journal.pone.0000571
Detection of microRNA Expression in Human Peripheral Blood Microvesicles, PLoS ONE, vol.15, issue.11, pp.3694-2008 ,
DOI : 10.1371/journal.pone.0003694.s003
Exosomal-like vesicles are present in human blood plasma, International Immunology, vol.17, issue.7, pp.879-887, 2005. ,
DOI : 10.1093/intimm/dxh267
Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer, Clinical Lung Cancer, vol.10, issue.1, pp.42-48, 2009. ,
DOI : 10.3816/CLC.2009.n.006
Patient-derived tumor-reactive antibodies as diagnostic markers for ovarian cancer, Gynecologic Oncology, vol.115, issue.1, pp.112-132, 2009. ,
DOI : 10.1016/j.ygyno.2009.06.031
Identification and proteomic profiling of exosomes in human urine, Proceedings of the National Academy of Sciences, vol.101, issue.36, pp.13368-73, 2004. ,
DOI : 10.1073/pnas.0403453101
Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes, Journal of the American Society of Nephrology, vol.20, issue.2, pp.363-379, 2009. ,
DOI : 10.1681/ASN.2008040406
Exosomes from human saliva as a source of microRNA biomarkers, Oral Diseases, vol.74, issue.Pt. 19, pp.34-42, 2010. ,
DOI : 10.1111/j.1601-0825.2009.01604.x
Nanostructural and Transcriptomic Analyses of Human Saliva Derived Exosomes, PLoS ONE, vol.64, issue.19, pp.8577-8577, 2010. ,
DOI : 10.1371/journal.pone.0008577.s002
CD24 is a marker of exosomes secreted into urine and amniotic fluid, Kidney International, vol.72, issue.9, pp.1095-102, 2007. ,
DOI : 10.1038/sj.ki.5002486
Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line, PLoS ONE, vol.21, issue.10, pp.13247-2010 ,
DOI : 10.1371/journal.pone.0013247.t001
Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs, Nucleic Acids Research, vol.38, issue.1, pp.215-239, 2010. ,
DOI : 10.1093/nar/gkp857
MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer, Gynecologic Oncology, vol.110, issue.1, pp.13-21, 2008. ,
DOI : 10.1016/j.ygyno.2008.04.033
Senescence-Associated Exosome Release from Human Prostate Cancer Cells, Cancer Research, vol.68, issue.19 ,
DOI : 10.1158/0008-5472.CAN-07-6538
Functional MicroRNA Is Transferred between Glioma Cells, Cancer Research, vol.70, issue.21, pp.8259-63, 2010. ,
DOI : 10.1158/0008-5472.CAN-10-0604
Microvesicles Derived from Adult Human Bone Marrow and Tissue Specific Mesenchymal Stem Cells Shuttle Selected Pattern of miRNAs, PLoS ONE, vol.44, issue.7, pp.11803-2010 ,
DOI : 10.1371/journal.pone.0011803.s004
Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche, Cancer Research, vol.71, issue.15, pp.5346-56, 2011. ,
DOI : 10.1158/0008-5472.CAN-11-0241
The elephant in the room: do microRNA-based therapies have a realistic chance of succeeding for brain tumors such as glioblastoma?, Journal of Neuro-Oncology, vol.435, issue.3, pp.429-465, 2011. ,
DOI : 10.1007/s11060-010-0449-5
The Therapeutic Potential of microRNAs . Innovations in Pharmaceutical Technology, pp.52-55, 2011. ,
Developing therapeutic microRNAs for cancer, Gene Therapy, vol.180, issue.12, 2011. ,
DOI : 10.1038/nature08956
Regression of murine lung tumors by the let-7 microRNA, Oncogene, vol.6, issue.11, pp.1580-1587, 2010. ,
DOI : 10.1016/j.cell.2007.10.054
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres, BMC Cancer, vol.36, issue.Suppl 1, pp.266-266, 2008. ,
DOI : 10.1046/j.1365-2184.36.s.1.6.x
Inhibition of microRNA with antisense oligonucleotides, Methods, vol.44, issue.1, pp.55-60, 2008. ,
DOI : 10.1016/j.ymeth.2007.11.001
Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection, Science, vol.327, issue.5962, pp.198-201, 2010. ,
DOI : 10.1126/science.1178178