A. Gharbi-ayachi, J. C. Labbe, A. Burgess, S. Vigneron, J. M. Strub et al., The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A, Science, vol.330, issue.6011, pp.1673-1677, 2010.
DOI : 10.1126/science.1197048
URL : https://hal.archives-ouvertes.fr/hal-00556511

T. Izumi and J. L. Maller, Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity., Molecular Biology of the Cell, vol.6, issue.2, pp.215-226, 1995.
DOI : 10.1091/mbc.6.2.215

S. Y. Kim, J. E. Ferrell, and . Jr, Substrate Competition as a Source of Ultrasensitivity in the Inactivation of Wee1, Cell, vol.128, issue.6, pp.1133-1145, 2007.
DOI : 10.1016/j.cell.2007.01.039

N. Kinoshita, H. Ohkura, and M. Yanagida, Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle, Cell, vol.63, issue.2, pp.405-415, 1990.
DOI : 10.1016/0092-8674(90)90173-C

N. Kinoshita, H. Yamano, H. Niwa, T. Yoshida, and M. Yanagida, Negative regulation of mitosis by the fission yeast protein phosphatase ppa2., Genes & Development, vol.7, issue.6, pp.1059-1071, 1993.
DOI : 10.1101/gad.7.6.1059

L. Krasinska, E. Besnard, E. Cot, C. Dohet, M. Mechali et al., Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus, The EMBO Journal, vol.280, issue.5, pp.758-769, 2008.
DOI : 10.1038/emboj.2008.16
URL : https://hal.archives-ouvertes.fr/hal-00266277

L. Krasinska, E. Cot, and D. Fisher, Selective chemical inhibition as a tool to study Cdk1 and Cdk2 functions in the cell cycle, Cell Cycle, vol.7, issue.12, pp.1702-1708, 2008.
DOI : 10.4161/cc.7.12.6101
URL : https://hal.archives-ouvertes.fr/inserm-00723361

A. Kumagai and W. G. Dunphy, Regulation of the cdc25 protein during the cell cycle in Xenopus extracts, Cell, vol.70, issue.1, pp.139-151, 1992.
DOI : 10.1016/0092-8674(92)90540-S

X. H. Lin, J. Walter, K. Scheidtmann, K. Ohst, J. Newport et al., Protein phosphatase 2A is required for the initiation of chromosomal DNA replication, Proceedings of the National Academy of Sciences, vol.95, issue.25, pp.14693-14698, 1998.
DOI : 10.1073/pnas.95.25.14693

T. Lorca, C. Bernis, S. Vigneron, A. Burgess, E. Brioudes et al., Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle, Journal of Cell Science, vol.123, issue.13, pp.2281-2291, 2010.
DOI : 10.1242/jcs.064527
URL : https://hal.archives-ouvertes.fr/hal-00509831

Y. Lu and F. R. Cross, Periodic Cyclin-Cdk Activity Entrains an Autonomous Cdc14 Release Oscillator, Cell, vol.141, issue.2, pp.268-279, 2010.
DOI : 10.1016/j.cell.2010.03.021

H. M. Mahbubani, J. P. Chong, S. Chevalier, P. Thommes, and J. J. Blow, Cell Cycle Regulation of the Replication Licensing System: Involvement of a Cdk-dependent Inhibitor, The Journal of Cell Biology, vol.107, issue.1, pp.125-135, 1997.
DOI : 10.1002/jez.1402620312

S. S. Margolis, J. A. Perry, C. M. Forester, L. K. Nutt, Y. Guo et al., Role for the PP2A/B56?? Phosphatase in Regulating 14-3-3 Release from Cdc25 to Control Mitosis, Cell, vol.127, issue.4, pp.759-773, 2006.
DOI : 10.1016/j.cell.2006.10.035

S. S. Margolis, S. Walsh, D. C. Weiser, M. Yoshida, S. Shenolikar et al., PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation, The EMBO Journal, vol.22, issue.21, pp.5734-5745, 2003.
DOI : 10.1093/emboj/cdg545

G. Maton, T. Lorca, J. A. Girault, R. Ozon, J. et al., Differential regulation of Cdc2 and Aurora-A in Xenopus oocytes: a crucial role of phosphatase 2A, Journal of Cell Science, vol.118, issue.11, pp.2485-2494, 2005.
DOI : 10.1242/jcs.02370

S. Mimura and H. Takisawa, Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase cdk, The EMBO Journal, vol.17, issue.19, pp.5699-5707, 1998.
DOI : 10.1093/emboj/17.19.5699

S. Mochida, S. Ikeo, J. Gannon, and T. Hunt, Regulated activity of PP2A???B55?? is crucial for controlling entry into and exit from mitosis in Xenopus egg extracts, The EMBO Journal, vol.9, issue.18, pp.2777-2785, 2009.
DOI : 10.1091/mbc.E07-11-1099

S. Mochida, S. L. Maslen, M. Skehel, and T. Hunt, Greatwall Phosphorylates an Inhibitor of Protein Phosphatase 2A That Is Essential for Mitosis, Science, vol.330, issue.6011, pp.1670-1673, 2010.
DOI : 10.1126/science.1195689

G. B. Moorhead, T. A. Haystead, and C. Mackintosh, Synthesis and use of the protein phosphatase affinity matrices microcystin-sepharose and microcystin-biotinsepharose, Methods Mol Biol, vol.365, pp.39-45, 2007.

P. R. Mueller, T. R. Coleman, and W. G. Dunphy, Cell cycle regulation of a Xenopus Wee1-like kinase., Molecular Biology of the Cell, vol.6, issue.1, pp.119-134, 1995.
DOI : 10.1091/mbc.6.1.119

J. Murphy, C. M. Crompton, S. Hainey, G. A. Codd, and C. J. Hutchison, The role of protein phosphorylation in the assembly of a replication competent nucleus: investigations in Xenopus egg extracts using the cyanobacterial toxin microcystin-LR, J Cell Sci, vol.108, pp.235-244, 1995.

B. Novak, O. Kapuy, M. R. Domingo-sananes, T. , and J. J. , Regulated protein kinases and phosphatases in cell cycle decisions, Current Opinion in Cell Biology, vol.22, issue.6, pp.801-808, 2010.
DOI : 10.1016/j.ceb.2010.07.001

B. Novak, T. , and J. J. , Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos, J Cell Sci, vol.106, pp.1153-1168, 1993.

P. Petersen, D. M. Chou, Z. You, T. Hunter, J. C. Walter et al., Protein Phosphatase 2A Antagonizes ATM and ATR in a Cdk2- and Cdc7-Independent DNA Damage Checkpoint, Molecular and Cellular Biology, vol.26, issue.5, 1997.
DOI : 10.1128/MCB.26.5.1997-2011.2006

J. R. Pomerening, E. D. Sontag, J. E. Ferrell, and . Jr, Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2, Nature Cell Biology, vol.5, issue.4, pp.346-351, 2003.
DOI : 10.1038/ncb954

T. A. Prokhorova, K. Mowrer, C. H. Gilbert, and J. C. Walter, DNA replication of mitotic chromatin in Xenopus egg extracts, Proceedings of the National Academy of Sciences, vol.100, issue.23, pp.13241-13246, 2003.
DOI : 10.1073/pnas.2336104100

M. J. Solomon, M. Glotzer, T. H. Lee, M. Philippe, and M. W. Kirschner, Cyclin activation of p34cdc2, Cell, vol.63, issue.5, pp.1013-1024, 1990.
DOI : 10.1016/0092-8674(90)90504-8

U. P. Strausfeld, M. Howell, P. Descombes, S. Chevalier, R. E. Rempel et al., Both cyclin A and cyclin E have S-phase promoting (SPF) activity in Xenopus egg extracts, J Cell Sci, vol.109, pp.1555-1563, 1996.

N. B. Trunnell, A. C. Poon, S. Y. Kim, J. E. Ferrell, and . Jr, Ultrasensitivity in the Regulation of Cdc25C by Cdk1, Molecular Cell, vol.41, issue.3, pp.263-274, 2010.
DOI : 10.1016/j.molcel.2011.01.012

A. H. Walsh, A. Cheng, and R. E. Honkanen, Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A, FEBS Letters, vol.376, issue.3, pp.230-234, 1997.
DOI : 10.1016/S0014-5793(97)01210-6

J. Walter, L. Sun, and J. Newport, Regulated Chromosomal DNA Replication in the Absence of a Nucleus, Molecular Cell, vol.1, issue.4, pp.519-529, 1998.
DOI : 10.1016/S1097-2765(00)80052-0

R. Wang, G. He, M. Nelman-gonzalez, C. L. Ashorn, G. E. Gallick et al., Regulation of Cdc25C by ERK-MAP Kinases during the G2/M Transition, Cell, vol.128, issue.6, pp.1119-1132, 2007.
DOI : 10.1016/j.cell.2006.11.053

M. Welcker, J. Singer, K. R. Loeb, J. Grim, A. Bloecher et al., Multisite Phosphorylation by Cdk2 and GSK3 Controls Cyclin E Degradation, Molecular Cell, vol.12, issue.2, pp.381-392, 2003.
DOI : 10.1016/S1097-2765(03)00287-9

S. Wicky, H. Tjandra, D. Schieltz, J. Yates, and D. R. Kellogg, The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase, Molecular Biology of the Cell, vol.22, issue.1, pp.20-32, 2011.
DOI : 10.1091/mbc.E10-06-0487

J. Q. Wu, J. Y. Guo, W. Tang, C. S. Yang, C. D. Freel et al., PP1-mediated dephosphorylation of phosphoproteins at mitotic exit is controlled by inhibitor-1 and PP1 phosphorylation, Nature Cell Biology, vol.12, issue.5, pp.644-651, 2009.
DOI : 10.1002/cne.903100204

J. Yu, Y. Zhao, Z. Li, S. Galas, and M. L. Goldberg, Greatwall Kinase Participates in the Cdc2 Autoregulatory Loop in Xenopus Egg Extracts, Molecular Cell, vol.22, issue.1, pp.83-91, 2006.
DOI : 10.1016/j.molcel.2006.02.022

L. Zou and B. Stillman, Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin, Science, vol.280, issue.5363, pp.593-596, 1998.
DOI : 10.1126/science.280.5363.593