Interest of a simple on-line screening registry for measuring ICU burden related to an Influenza pandemic.

Jean-Christophe Marie Richard; Tài Pham; Christian Brun-Buisson; Jean Reignier; Alain Mercat; Gaëtan Beduneau; Bernard Régnier; Bruno Mourvillier; Christophe Guitton; Matthias Castanier; Alain Combes; Yves Le Tulzo; Laurent Brochard

inserm-00723061, version 1

Interest of a simple on-line screening registry for measuring ICU burden related to an Influenza pandemic.
Richard J.-C. Marie, Pham T., Brun-Buisson C., Reignier J., Mercat A., Beduneau G., Régnier B., Mourvillier B., Guitton C., Castanier M. et al
Critical Care 16, 4 (2012) R118 - http://www.hal.inserm.fr/inserm-00723061

PMID: identifiant
de la référence Pubmed :

(22776231)

titre :

Interest of a simple on-line screening registry for measuring ICU burden related to an Influenza pandemic.

auteur(s) :

Jean-Christophe Richard^{1, 2, 3}, Tài Pham (

) ⁴, Christian Brun-Buisson^{4, 5}, Jean Reignier⁶, Alain Mercat^{7, 8}, Gaëtan Beduneau^{1, 3}, Bernard Régnier⁹, Bruno Mourvillier⁹, Christophe Guitton¹⁰, Matthias Castanier¹¹, Alain Combes¹², Yves Tulzo^{13, 14}, Laurent Brochard², for the REVA study group Collaboration(s)

laboratoire :

1 :	Service de Réanimation Médicale [Rouen]

CHU Rouen – Hôpital Charles Nicolle

1 rue de Germont, Rouen, 76031

France

2 :	Department of Intensive Care

Geneva University Hospital and Geneva University

4 Rue Gabrielle-Perret-Gentil, Geneva, 1205

Suisse

3 :	Groupe de Recherche sur le Handicap Ventilatoire

Université de Rouen : EA3830 – CHU Rouen – IRIB Haute-Normandie

France

4 :	Service de réanimation médicale

Assistance publique - Hôpitaux de Paris (AP-HP) – Hôpital Henri Mondor – Université Paris-Est Créteil Val-de-Marne (UPEC)

Créteil

France

5 :	Institut Mondor de Recherche Biomédicale

INSERM : U955 – Université Paris-Est Créteil Val-de-Marne (UPEC) – IFR10

8 rue du Général Sarrail, 94010 Créteil

France

6 :	Service de Réanimation Polyvalente

CH Départemental Vendée

Les Oudairies, La Roche sur Yon, 85000

France

7 :	Service de Réanimation Médicale et de médecine hyperbare

CHU Angers

4 rue Larrey, Angers, 49933

France

8 :	LUNAM

PRES Université Nantes Angers Le Mans [UNAM]

19 bis rue La Nouë Bras de Fer, Nantes, 44200

France

9 :	Service de réanimation médicale et infectieuse

Assistance publique - Hôpitaux de Paris (AP-HP) – Hôpital Bichat - Claude Bernard – Université Paris VII - Paris Diderot

France

10 :	Service de Réanimation Médicale

CHU Nantes – Hôtel-Dieu

1 place Alexis-Ricordeau, Nantes, 44093

France

11 :	Service de Réanimation, détresses respiratoires et infections sévères

AP-HM – Hôpital nord

Chemin des Bourelly, Marseille, 13915

France

12 :	Service de Réanimation Médicale [Pitié-Salpétrière]

AP-HP – Hôpital Pitié-Salpêtrière

47 Boulevard de l'Hôpital, Paris, 75013

France

13 :	Service de Maladies Infectieuses et Réanimation médicale

CHU Rennes – Hôpital Pontchaillou

Rennes, 35033

France

14 :	CIC - Rennes

INSERM : CIC203 – Université de Rennes 1 – Biosit

Hôpital Pontchaillou, Rue Henri Le Guilloux 35033 RENNES CEDEX 9

France

résumé :

ABSTRACT: INTRODUCTION: The specific burden imposed on Intensive Care Units (ICUs) during the A/H1N1 influenza 2009 pandemic has been poorly explored. An on-line screening registry allowed a daily report of ICU beds occupancy rate by flu infected patients (Flu-OR) admitted in French ICUs. METHODS: A prospective inception cohort study with results of an on-line screening registry designed for daily assessment of ICU burden. RESULTS: Among the 108 centers participating to the French H1N1 research network on mechanical ventilation (REVA) - French Society of Intensive Care (SRLF) registry, 69 ICUs belonging to seven large geographical areas voluntarily participated to a website screening-registry. The aim was to daily assess the ICU beds occupancy rate by influenza-infected and non-infected patients for at least three weeks. 391 critically ill infected patients were enrolled in the cohort, representing a subset of 35% of the whole French 2009 pandemic cohort; 73% were mechanically ventilated, 13% required extra corporal membrane oxygenation (ECMO) and 22% died. The global Flu-OR in these ICUs was only 7.6%, but it exceeded a predefined 15% critical threshold in 32 ICUs for a total of 103 weeks. Flu-ORs were significantly higher in University than in non University hospitals. The peak ICU burden was poorly predicted by observations obtained at the level of large geographical areas. CONCLUSIONS: The peak Flu-OR during the pandemic significantly exceeded a 15% critical threshold in almost half of the ICUs, with an uneven distribution with time, geographical areas and between University and non University hospitals. An on-line assessment of Flu-OR via a simple dedicated registry may contribute to better match resources and needs.

domaine :

Sciences du Vivant/Médecine humaine et pathologie/Maladies infectieuses

langue du texte
intégral :

Anglais

ISSN :

1466-609X

type de publication :

Articles dans des revues avec comité de lecture

DOI :

10.1186/cc11412

journal :

Critical Care (Crit Care)
Publisher	BioMed Central
ISSN	1364-8535

Audience :

internationale

date de publication :

09/07/2012

date de publication
électronique :

09/07/2012

volume :

numéro :

page, identifiant, ... :

R118

contrat, financement :

The REVA registry was funded in part by the French Ministry of Health, the Inserm-Institut des Maladies Infectieuses, and the SRLF.

Liste des fichiers attachés à ce document :

PDF

cc11412.pdf

(590.3 KB)

ANNEX

cc11412.xml

(66 KB)


inserm-00723061, version 1
http://www.hal.inserm.fr/inserm-00723061
oai:www.hal.inserm.fr:inserm-00723061
Contributeur : Ed. BMC <>
Soumis le : Mardi 7 Août 2012, 13:05:14
Dernière modification le : Mardi 7 Août 2012, 15:34:01