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Vapor phase mediated cellular uptake of sub 5 nm nanoparticles
Serdiuk T., Lysenko V., Skryshevsky V., Géloën A.
Nanoscale Research Letters 7, 1 (2012) 212 - http://www.hal.inserm.fr/inserm-00709108
 (22494848) 
Vapor phase mediated cellular uptake of sub 5 nm nanoparticles
Tetiana Serdiuk () 1, 2, 3, Vladimir Lysenko2, Valery Skryshevsky1, Alain Géloën3
1 :  Institute of High Technologies
Taras Shevchenko National University of Kyiv
64, Volodymyrs'ka Str, 01601 Kyiv
Ukraine
2 :  INL - Institut des Nanotechnologies de Lyon - Site de l'INSA
http://inl.cnrs.fr
CNRS : UMR5270 – Ecole Centrale de Lyon – Institut National des Sciences Appliquées (INSA) - Lyon – Université Claude Bernard - Lyon I
7, avenue Jean Capelle 69621 VILLEURBANNE cedex
France
3 :  CARMEN - Laboratoire de recherche en cardiovasculaire, métabolisme, diabétologie et nutrition
http://ifr62.univ-lyon1.fr/laboratoires.php?id=45
INSERM : U1060 – Institut national de la recherche agronomique (INRA) – Institut National des Sciences Appliquées (INSA) - Lyon – Université Claude Bernard - Lyon I – Hospices Civils de Lyon
Faculté de Médecine Lyon Sud - BP 12 - 165 Chemin du Grand Revoyet - 69921 Oullins cedex INSA, Bât. IMBL, La Doua - 11 Avenue Jean Capelle - 69621 Villeurbanne Cedex
France
Nanoparticles became an important and wide-used tool for cell imaging because of their unique optical properties. Although the potential of nanoparticles (NPs) in biology is promising, a number of questions concerning the safety of nanomaterials and the risk/benefit ratio of their usage are open. Here, we have shown that nanoparticles produced from silicon carbide (NPs) dispersed in colloidal suspensions are able to penetrate into surrounding air environment during the natural evaporation of the colloids and label biological cells via vapor phase. Natural gradual size-tuning of NPs in dependence to the distance from the NP liquid source allows progressive shift of the fluorescence color of labeled cells in the blue region according to the increase of the distance from the NP suspension. This effect may be used for the soft vapor labeling of biological cells with the possibility of controlling the color of fluorescence. However, scientists dealing with the colloidal NPs have to seriously consider such a NP's natural transfer in order to protect their own health as well as to avoid any contamination of the control samples.
Sciences du Vivant/Ingénierie biomédicale
Anglais

Articles dans des revues avec comité de lecture
10.1186/1556-276X-7-212
Nanoscale Research Letters
Publisher SpringerOpen
ISSN 1931-7573 (eISSN : 1556-276X)
internationale
2012
11/04/2012
7
1
212

nanoparticles – cell labeling – fluorescence – contamination
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1556-276X-7-212-S2.DOC(39 KB)

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