C. Waddington, The strategy of the genes; A discussion of some aspects of theoretical biology, 1957.

J. De-visser, J. Hermisson, G. Wagner, L. Meyers, and H. Bagheri-chaichian, PERSPECTIVE: EVOLUTION AND DETECTION OF GENETIC ROBUSTNESS, Evolution, vol.3, issue.9, pp.1959-1972, 2003.
DOI : 10.1086/280260

W. Scharloo, Canalization: Genetic and Developmental Aspects, Annual Review of Ecology and Systematics, vol.22, issue.1, pp.65-93, 1991.
DOI : 10.1146/annurev.es.22.110191.000433

S. Stearns and T. Kawecki, Fitness Sensitivity and the Canalization of Life-History Traits, Evolution, vol.48, issue.5, pp.1438-1450, 1994.
DOI : 10.2307/2410238

J. Hermisson and G. Wagner, The Population Genetic Theory of Hidden Variation and Genetic Robustness, Genetics, vol.168, issue.4, pp.2271-2284, 2004.
DOI : 10.1534/genetics.104.029173

G. Wagner, G. Booth, and H. Bagheri-chaichian, A Population Genetic Theory of Canalization, Evolution, vol.51, issue.2, pp.329-347, 1997.
DOI : 10.2307/2411105

C. Wilke, Evolution of digital organisms at high mutation rates leads to survival of the flattest, Nature, vol.412, issue.6844, pp.331-333, 2001.
DOI : 10.1038/35085569

J. Drake and J. Holland, Mutation rates among RNA viruses, Proceedings of the National Academy of Sciences, vol.96, issue.24, pp.13910-13913, 1999.
DOI : 10.1073/pnas.96.24.13910

M. Bretscher, C. Althaus, V. Muller, and S. Bonhoeffer, Recombination in HIV and the evolution of drug resistance: for better or for worse?, BioEssays, vol.190, issue.2, pp.180-188, 2004.
DOI : 10.1002/bies.10386

R. Froissart, C. Wilke, R. Montville, S. Remold, and L. Chao, Co-infection Weakens Selection Against Epistatic Mutations in RNA Viruses, Genetics, vol.168, issue.1, pp.9-19, 2004.
DOI : 10.1534/genetics.104.030205

I. Novella, D. Reissig, and C. Wilke, Density-Dependent Selection in Vesicular Stomatitis Virus, Journal of Virology, vol.78, issue.11, pp.5799-5804, 2004.
DOI : 10.1128/JVI.78.11.5799-5804.2004

D. Krakauer and J. Plotkin, Redundancy, antiredundancy, and the robustness of genomes, Proceedings of the National Academy of Sciences, vol.99, issue.3, pp.1405-1409, 2002.
DOI : 10.1073/pnas.032668599

Z. Gu, L. Steinmetz, X. Gu, C. Scharfe, and R. Davis, Role of duplicate genes in genetic robustness against null mutations, Nature, vol.95, issue.6918, pp.63-66, 2003.
DOI : 10.1038/nature00935

P. Turner and L. Chao, Sex and the evolution of intrahost competition in RNA virus phi6, Genetics, vol.150, pp.523-532, 1998.

P. Turner and L. Chao, Prisoner's dilemma in an RNA virus, Nature, vol.398, issue.6726, pp.441-443, 1999.
DOI : 10.1038/18913

L. Chao, Fitness of RNA virus decreased by Muller's ratchet, Nature, vol.348, issue.6300, pp.454-455, 1990.
DOI : 10.1038/348454a0

C. Burch and L. Chao, Evolution by small steps and rugged landscapes in the RNA virus phi 6, Genetics, vol.151, pp.921-927, 1999.

C. Burch and L. Chao, Epistasis and Its Relationship to Canalization in the RNA Virus ??6, Genetics, vol.167, issue.2, pp.559-567, 2004.
DOI : 10.1534/genetics.103.021196

G. Gibson and G. Wagner, Canalization in evolutionary genetics: a stabilizing theory?, BioEssays, vol.139, issue.4, pp.372-380, 2000.
DOI : 10.1002/(SICI)1521-1878(200004)22:4<372::AID-BIES7>3.0.CO;2-J

R. Littell, G. Milliken, W. Stroup, and R. Wolfinger, SAS system for mixed models, 1996.

D. Hartl and C. Taubes, Compensatory Nearly Neutral Mutations: Selection without Adaptation, Journal of Theoretical Biology, vol.182, issue.3, pp.303-309, 1996.
DOI : 10.1006/jtbi.1996.0168

L. Chao, C. Rang, and L. Wong, Distribution of Spontaneous Mutants and Inferences about the Replication Mode of the RNA Bacteriophage ??6, Journal of Virology, vol.76, issue.7, pp.3276-3281, 2002.
DOI : 10.1128/JVI.76.7.3276-3281.2002

R. Lenski, M. Rose, S. Simpson, and S. Tadler, Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations, The American Naturalist, vol.138, issue.6, pp.1315-1341, 1991.
DOI : 10.1086/285289
URL : https://hal.archives-ouvertes.fr/hal-00171694

M. Travisano, Adaptation and divergence in experimental populations of the bacterium Escherichia coli: The roles of environment, phylogeny and chance [dissertation]. East Lansing (Michigan): Michigan State University, p.9418079, 1993.

A. Wagner, Redundant gene functions and natural selection, Journal of Evolutionary Biology, vol.12, issue.1, pp.1-16, 1999.
DOI : 10.1046/j.1420-9101.1999.00008.x

L. Mindich, J. Cohen, and M. Weisburd, Isolation of nonsense suppressor mutants in Pseudomonas, J Bacteriol, vol.126, pp.177-182, 1976.

S. Remold and R. Lenski, Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli, Nature Genetics, vol.36, issue.4, pp.423-426, 2004.
DOI : 10.1038/ng1324