Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function, Physiological Reviews, vol.89, issue.1, pp.73-120, 2009. ,
DOI : 10.1152/physrev.00015.2008
Neuronal alpha-bungarotoxin receptors are alpha7 subunit homomers, J Neurosci, vol.20, pp.133-139, 2000. ,
Structures of neuronal nicotinic receptors, Neuronal nicotinic receptors, pp.101-162, 2000. ,
ION CHANNEL STRUCTUREEMERGING STRUCTURE OF THE NICOTINIC ACETYLCHOLINE RECEPTORS, Nature Reviews Neuroscience, vol.3, issue.2, pp.102-114, 2002. ,
DOI : 10.1038/nrn731
Refined Structure of the Nicotinic Acetylcholine Receptor at 4?? Resolution, Journal of Molecular Biology, vol.346, issue.4, pp.967-989, 2005. ,
DOI : 10.1016/j.jmb.2004.12.031
The nicotinic acetylcholine receptor gene family of the nematode Caenorhabditis elegans: an update on nomenclature, Invertebrate Neuroscience, vol.440, issue.2, pp.129-131, 2007. ,
DOI : 10.1007/s10158-007-0049-z
Acetylcholine, WormBook, vol.30, pp.1-21, 2007. ,
DOI : 10.1895/wormbook.1.131.1
Levamisole-resitant mutants of the nematode Caenorhabditis elegans appear to lack pharmacological acetylcholine receptors, Neuroscience, vol.5, issue.6, pp.967-989, 1980. ,
DOI : 10.1016/0306-4522(80)90180-3
Caenorhabditis elegans levamisole resistance genes lev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits, J Neurosci, vol.17, pp.5843-5857, 1997. ,
The Caenorhabditis elegans unc-63 Gene Encodes a Levamisole-sensitive Nicotinic Acetylcholine Receptor ?? Subunit, Journal of Biological Chemistry, vol.279, issue.41, pp.42476-42783, 2004. ,
DOI : 10.1074/jbc.M404370200
URL : https://hal.archives-ouvertes.fr/hal-00198541
The Caenorhabditis elegans lev-8 gene encodes a novel type of nicotinic acetylcholine receptor alpha subunit, Journal of Neurochemistry, vol.19, issue.1, pp.1-9, 2005. ,
DOI : 10.1038/nature00891
Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: Nicotinic acetylcholine receptors, a case study, International Journal for Parasitology, vol.36, issue.6, pp.617-624, 2006. ,
DOI : 10.1016/j.ijpara.2006.01.016
Eight genes are required for functional reconstitution of the Caenorhabditis elegans levamisole-sensitive acetylcholine receptor, Proceedings of the National Academy of Sciences, vol.105, issue.47, pp.18590-18595, 2008. ,
DOI : 10.1073/pnas.0806933105
Functional genomics of the nicotinic acetylcholine receptor gene family of the nematode,Caenorhabditis elegans, BioEssays, vol.129, issue.1, pp.39-49, 2004. ,
DOI : 10.1002/bies.10377
The Structure of the Ventral Nerve Cord of Caenorhabditis elegans, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.275, issue.938, pp.327-348, 1976. ,
DOI : 10.1098/rstb.1976.0086
Genes required for GABA function in Caenorhabditis elegans, Nature, vol.364, issue.6435, pp.334-337, 1993. ,
DOI : 10.1038/364334a0
Molecular cloning and functional co-expression of a Caenorhabditis elegans nicotinic acetylcholine receptor subunit (acr-2), Recept Channels, vol.3, pp.107-115, 1995. ,
ACR- 3, a Caenorhabditis elegans nicotinic acetylcholine receptor subunit. Molecular cloning and functional expression, Recept Channels, vol.5, pp.149-158, 1997. ,
An open-channel blocker interacts with adjacent turns of ??-helices in the nicotinic acetylcholine receptor, Neuron, vol.4, issue.1, pp.87-95, 1990. ,
DOI : 10.1016/0896-6273(90)90445-L
Ligand-gated ion channels: mechanisms underlying ion selectivity, Progress in Biophysics and Molecular Biology, vol.86, issue.2, pp.161-204, 2004. ,
DOI : 10.1016/j.pbiomolbio.2003.09.002
A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans, Neuron, vol.14, issue.4, pp.871-877, 1995. ,
DOI : 10.1016/0896-6273(95)90231-7
New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome, Human Molecular Genetics, vol.5, issue.9, pp.1217-1227, 1996. ,
DOI : 10.1093/hmg/5.9.1217
The acetylcholine receptor of the neuromuscular junction recognizes mecamylamine as a noncompetitive antagonist, Mol Pharmacol, vol.28, pp.128-137, 1985. ,
An RNAi Screen Identifies Genes that Regulate GABA Synapses, Neuron, vol.58, issue.3, pp.346-361, 2008. ,
DOI : 10.1016/j.neuron.2008.02.019
Further studies on the nature and causes of gene mutations, Proc 6th Int Congr Genet, vol.1, pp.213-255, 1932. ,
The Structure of the Nervous System of the Nematode Caenorhabditis elegans, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.314, issue.1165, pp.1-340, 1986. ,
DOI : 10.1098/rstb.1986.0056
Nicotinic Receptor Interloop Proline Anchors ??1-??2 and Cys loops in Coupling Agonist Binding to Channel Gating, The Journal of General Physiology, vol.385, issue.2, pp.265-278, 2008. ,
DOI : 10.1006/jmbi.1996.0309
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483337
One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction, Nature Neuroscience, vol.2, issue.9, pp.791-797, 1999. ,
DOI : 10.1038/12160
The GABA nervous system in C. elegans, Trends in Neurosciences, vol.27, issue.7, pp.407-414, 2004. ,
DOI : 10.1016/j.tins.2004.05.005
Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50, The EMBO Journal, vol.119, issue.20, pp.4313-4323, 2007. ,
DOI : 10.1038/sj.emboj.7601858
Expression Profiling of GABAergic Motor Neurons in Caenorhabditis elegans, Current Biology, vol.15, issue.4, pp.340-346, 2005. ,
DOI : 10.1016/j.cub.2005.02.025
Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans, The EMBO Journal, vol.19, issue.14, pp.2566-2578, 2005. ,
DOI : 10.1038/sj.emboj.7600741
The C.elegansric-3 gene is required for maturation of nicotinic acetylcholine receptors, The EMBO Journal, vol.21, issue.5, pp.1012-1020, 2002. ,
DOI : 10.1093/emboj/21.5.1012
Galanthamine and Non-competitive Inhibitor Binding to ACh-binding Protein: Evidence for a Binding Site on Non-??-subunit Interfaces of Heteromeric Neuronal Nicotinic Receptors, Journal of Molecular Biology, vol.369, issue.4, pp.895-901, 2007. ,
DOI : 10.1016/j.jmb.2007.03.067
Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic, Nature, vol.359, issue.6395, pp.500-505, 1992. ,
DOI : 10.1038/359500a0
The multiple phenotypes of allosteric receptor mutants., Proceedings of the National Academy of Sciences, vol.93, issue.5, pp.1853-1858, 1996. ,
DOI : 10.1073/pnas.93.5.1853
Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor., Proceedings of the National Academy of Sciences, vol.90, issue.15, pp.6971-6975, 1993. ,
DOI : 10.1073/pnas.90.15.6971
The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development, J Neurosci, vol.19, pp.539-548, 1999. ,
The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor, J Neurosci, vol.19, pp.5348-5359, 1999. ,
SLO-1 Potassium Channels Control Quantal Content of Neurotransmitter Release at the C. elegans Neuromuscular Junction, Neuron, vol.32, issue.5, pp.867-881, 2001. ,
DOI : 10.1016/S0896-6273(01)00522-0
The multifaceted role of inhibition in epilepsy: seizure-genesis through excessive GABAergic inhibition in autosomal dominant nocturnal frontal lobe epilepsy, Current Opinion in Neurology, vol.21, issue.2, pp.155-160, 2008. ,
DOI : 10.1097/WCO.0b013e3282f52f5f
Naturally occurring genetic variability in the nicotinic acetylcholine receptor alpha4 and alpha7 subunit genes and phenotypic diversity in humans and mice, Frontiers in Bioscience, vol.13, issue.13, pp.477-491, 2008. ,
DOI : 10.2741/2694
The genetics of Caenorhabditis elegans, Genetics, vol.77, pp.71-94, 1974. ,
Rapid gene mapping in Caenorhabditis elegans using a high density polymorphism map, Nature Genetics, vol.28, issue.2, pp.160-164, 2001. ,
DOI : 10.1038/88878
Rapid single nucleotide polymorphism mapping in C. elegans, BMC Genomics, vol.6, issue.1, p.118, 2005. ,
DOI : 10.1186/1471-2164-6-118
Molecular cloning: a laboratory manual, 1989. ,
Toward a physical map of the genome of the nematode Caenorhabditis elegans, Proceedings of the National Academy of Sciences, vol.83, issue.20, pp.7821-7825, 1986. ,
DOI : 10.1073/pnas.83.20.7821
Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences, EMBO J, vol.10, pp.3959-3970, 1991. ,
Activation of nicotinic receptors uncouples a developmental timer from the molting timer in C. elegans, Development, vol.133, issue.11, pp.2211-2222, 2006. ,
DOI : 10.1242/dev.02392
The Sensory Circuitry for Sexual Attraction in C. elegans Males, Current Biology, vol.17, issue.21, pp.1847-1857, 2007. ,
DOI : 10.1016/j.cub.2007.09.011
Negative Surface Charge Near Sodium Channels of Nerve: Divalent Ions, Monovalent Ions, and pH [and Discussion], Philosophical Transactions of the Royal Society B: Biological Sciences, vol.270, issue.908, pp.301-318, 1975. ,
DOI : 10.1098/rstb.1975.0011