Divergent Host Responses during Primary Simian Immunodeficiency Virus SIVsm Infection of Natural Sooty Mangabey and Nonnatural Rhesus Macaque Hosts, Journal of Virology, vol.79, issue.7, pp.4043-4054, 2005. ,
DOI : 10.1128/JVI.79.7.4043-4054.2005
Simian immunodeficiency virus disease course is predicted by the extent of virus replication during primary infection, J Virol, vol.73, pp.4829-4839, 1999. ,
Viral Dynamics of Acute HIV-1 Infection, The Journal of Experimental Medicine, vol.14, issue.6, pp.841-850, 1999. ,
DOI : 10.1126/science.274.5290.1167
Viral dynamics of primary viremia and antiretroviral therapy in simian immunodeficiency virus infection, J Virol, vol.71, pp.7518-7525, 1997. ,
Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection, Nature, vol.82, issue.7037, pp.1093-1097, 2005. ,
DOI : 10.1084/jem.164.1.280
T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract, The Journal of Experimental Medicine, vol.72, issue.6, pp.749-759, 2004. ,
DOI : 10.4049/jimmunol.167.12.6711
Gastrointestinal Tract as a Major Site of CD4+ T Cell Depletion and Viral Replication in SIV Infection, Science, vol.280, issue.5362, pp.427-431, 1998. ,
DOI : 10.1126/science.280.5362.427
The Immunopathogenesis of Human- Immunodeficiency-Virus Infection, N Engl J Med, vol.328, pp.327-335, 1993. ,
Acute Human Immunodeficiency Virus Type 1 Infection, New England Journal of Medicine, vol.339, issue.1, pp.33-39, 1998. ,
DOI : 10.1056/NEJM199807023390107
Kinetics of human immunodeficiency virus type 1 (HIV-1) DNA and RNA synthesis during primary HIV-1 infection., Proceedings of the National Academy of Sciences, vol.90, issue.14, pp.6405-6409, 1993. ,
DOI : 10.1073/pnas.90.14.6405
Temporal Association of Cellular Immune-Responses with the Initial Control of Viremia in Primary Human-Immunodeficiency-Virus Type-1 Syndrome, J Virol, vol.68, pp.4650-4655, 1994. ,
Immunopathogenic Events in Acute Infection of Rhesus-Monkeys with Simian Immunodeficiency Virus of Macaques, J Virol, vol.68, pp.2362-2370, 1994. ,
Simian Immunodeficiency Virus-Specific CD8+ Lymphocyte-Response in Acutely Infected Rhesus-Monkeys, J Virol, vol.67, pp.1707-1711, 1993. ,
Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution, Journal of Virology, vol.79, issue.21, pp.13239-13249, 2005. ,
DOI : 10.1128/JVI.79.21.13239-13249.2005
Control of Viremia in Simian Immunodeficiency Virus Infection by CD8+ Lymphocytes, Science, vol.283, issue.5403, pp.857-860, 1999. ,
DOI : 10.1126/science.283.5403.857
T Cell Depletion in Simian Immunodeficiency Virus???infected Macaques, The Journal of Experimental Medicine, vol.41, issue.6, pp.991-998, 1999. ,
DOI : 10.1007/BF00918085
Contribution of CD8+ T Cells to Containment of Viral Replication and Emergence of Mutations in Mamu-A*01-Restricted Epitopes in Simian Immunodeficiency Virus-Infected Rhesus Monkeys, Journal of Virology, vol.82, issue.11, pp.5631-5635, 2008. ,
DOI : 10.1128/JVI.02749-07
Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules, Blood, vol.104, issue.7, pp.2087-2094, 2004. ,
DOI : 10.1182/blood-2004-02-0696
Tatspecific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia, Nature, vol.407, pp.386-390, 2000. ,
Dressed to kill? A review of why antiviral CD8 T lymphocytes fail to prevent progressive immunodeficiency in HIV-1 infection, Blood, vol.98, issue.6, pp.1667-1677, 2001. ,
DOI : 10.1182/blood.V98.6.1667
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression, Nature, vol.170, issue.7109, pp.350-354, 2006. ,
DOI : 10.1126/science.274.5284.94
Natural Killer Cells in Perinatally HIV-1-Infected Children Exhibit Less Degranulation Compared to HIV-1-Exposed Uninfected Children and Their Expression of KIR2DL3, NKG2C, and NKp46 Correlates with Disease Severity, The Journal of Immunology, vol.179, issue.5, pp.3362-3370, 2007. ,
DOI : 10.4049/jimmunol.179.5.3362
T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function, The Journal of Experimental Medicine, vol.139, issue.1, pp.63-75, 2000. ,
DOI : 10.1086/314868
Failing immune control as a result of impaired CD8+ T-cell maturation: CD27 might provide a clue, Trends in Immunology, vol.23, issue.12, pp.586-591, 2002. ,
DOI : 10.1016/S1471-4906(02)02326-8
Inefficient Cytotoxic T Lymphocyte???Mediated Killing of HIV-1???Infected Cells In Vivo, PLoS Biology, vol.76, issue.4, pp.583-592, 2006. ,
DOI : 10.1371/journal.pbio.0040090.sd001
NK CELL RECOGNITION, Annual Review of Immunology, vol.23, issue.1, pp.225-274, 2005. ,
DOI : 10.1146/annurev.immunol.23.021704.115526
Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection, Blood, vol.106, issue.10, pp.3366-3369, 2005. ,
DOI : 10.1182/blood-2005-03-1100
Altered distribution of natural killer cell subsets identified by CD56, CD27 and CD70 in primary and chronic human immunodeficiency virus-1 infection, Immunology, vol.172, issue.0, pp.164-170, 2008. ,
DOI : 10.1038/ni1395
In Vivo Natural Killer Cell Depletion during Primary Simian Immunodeficiency Virus Infection in Rhesus Monkeys, Journal of Virology, vol.82, issue.13, pp.6758-6761, 2008. ,
DOI : 10.1128/JVI.02277-07
Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity, Journal of General Virology, vol.88, issue.1, pp.242-250, 2007. ,
DOI : 10.1099/vir.0.82125-0
HIV escape from natural killer cytotoxicity: nef inhibits NKp44L expression on CD4+ T cells, AIDS, vol.23, issue.9, pp.1077-1087, 2009. ,
DOI : 10.1097/QAD.0b013e32832cb26b
URL : https://hal.archives-ouvertes.fr/pasteur-00458079
Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS, Nature Genetics, vol.31, pp.429-434, 2002. ,
DOI : 10.1038/ng934
Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals, AIDS, vol.22, issue.5, pp.595-599, 2008. ,
DOI : 10.1097/QAD.0b013e3282f56b23
Differential natural killer cell???mediated inhibition of HIV-1 replication based on distinct KIR/HLA subtypes, The Journal of Experimental Medicine, vol.157, issue.12, pp.3027-3036, 2007. ,
DOI : 10.1016/S0065-2776(08)60600-8
HLA Class I Subtype-Dependent Expansion of KIR3DS1+ and KIR3DL1+ NK Cells during Acute Human Immunodeficiency Virus Type 1 Infection, Journal of Virology, vol.83, issue.13, pp.6798-6805, 2009. ,
DOI : 10.1128/JVI.00256-09
Genotypes Influence NK Cell Function Following Stimulation with HLA-Devoid Cells, The Journal of Immunology, vol.184, issue.4, pp.2057-2064, 2010. ,
DOI : 10.4049/jimmunol.0902621
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1, Nature Genetics, vol.36, issue.6, pp.733-740, 2007. ,
DOI : 10.1038/ni845
Role of Natural Killer Cells in a Cohort of Elite Suppressors: Low Frequency of the Protective KIR3DS1 Allele and Limited Inhibition of Human Immunodeficiency Virus Type 1 Replication In Vitro, Journal of Virology, vol.83, issue.10, pp.5028-5034, 2009. ,
DOI : 10.1128/JVI.02551-08
Natural-Killer-Cell Responses in Homosexual Men with Early Hiv-Infection, J Acquir Immune Defic Syndr Hum Retrovirol, vol.3, pp.669-676, 1990. ,
Natural-Killer- Cell Immunodeficiency in HIV Disease Is Manifest by Profoundly Decreased Numbers of CD16(+)CD56(+) Cells and Expansion of A Population of CD16(Dim)CD56(-) Cells with Low Lytic Activity, J Acquir Immune Defic Syndr Hum Retrovirol, vol.10, pp.331-340, 1995. ,
Subset, AIDS Research and Human Retroviruses, vol.6, issue.12, pp.1451-1457, 1990. ,
DOI : 10.1089/aid.1990.6.1451
Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection, Proceedings of the National Academy of Sciences, vol.102, issue.51, pp.18514-18519, 2005. ,
DOI : 10.1073/pnas.0504658102
Rapid evolution of the neutralizing antibody response to HIV type 1 infection, Proceedings of the National Academy of Sciences, vol.100, issue.7, pp.4144-4149, 2003. ,
DOI : 10.1073/pnas.0630530100
Neutralizing Antibody Responses against Autologous and Heterologous Viruses in Acute versus Chronic Human Immunodeficiency Virus (HIV) Infection: Evidence for a Constraint on the Ability of HIV To Completely Evade Neutralizing Antibody Responses, Journal of Virology, vol.80, issue.12, pp.6155-6164, 2006. ,
DOI : 10.1128/JVI.00093-06
Development of the antibody response in acute HIV-1 infection, AIDS, vol.18, issue.3, pp.371-381, 2004. ,
DOI : 10.1097/00002030-200402200-00002
Evaluation of CD8+ T-cell and antibody responses following transient increased viraemia in rhesus macaques infected with live, attenuated simian immunodeficiency virus, Journal of General Virology, vol.86, issue.12, pp.3375-3384, 2005. ,
DOI : 10.1099/vir.0.81206-0
Antiviral Antibodies Are Necessary for Control of Simian Immunodeficiency Virus Replication, Journal of Virology, vol.81, issue.10, pp.5024-5035, 2007. ,
DOI : 10.1128/JVI.02444-06
Limited ability of humoral immune responses in control of viremia during infection with SIVsmmD215 strain, Blood, vol.113, issue.18, pp.4250-4261, 2009. ,
DOI : 10.1182/blood-2008-09-177741
Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals, The Journal of Experimental Medicine, vol.70, issue.8, pp.1797-1805, 2008. ,
DOI : 10.1128/JVI.79.17.11214-11224.2005
Reduction of HIV Concentration During Acute Infection: Independence from a Specific Immune Response, Science, vol.271, issue.5248, pp.497-499, 1996. ,
DOI : 10.1126/science.271.5248.497
Virus- Specific CD8+ Cytotoxic T-Lymphocyte Activity Associated with Control of Viremia in Primary Human-Immunodeficiency-Virus Type-1 Infection, J Virol, vol.68, pp.6103-6110, 1994. ,
Shutting down HIV, Nature, vol.370, issue.6489, p.416, 1994. ,
DOI : 10.1038/370416a0
Early Viremia and Immune Responses in Vertical Human Immunodeficiency Virus Type 1 Infection, Journal of Infectious Diseases, vol.167, issue.5, pp.1008-1013, 1993. ,
DOI : 10.1093/infdis/167.5.1008
Effects of cyclosporin on T-cell subsets in human immunodeficiency virus disease, Clinical Immunology and Immunopathology, vol.47, issue.2, 1988. ,
DOI : 10.1016/0090-1229(88)90071-2
Editorial: Reducing T Cell Activation As A Therapy For Human Immunodeficiency Virus Infection, Journal of Infectious Diseases, vol.171, issue.3, pp.521-522, 1995. ,
DOI : 10.1093/infdis/171.3.521
1???year follow-up of the use of hydroxycarbamide and didanosine in HIV infection, The Lancet, vol.348, issue.9021, pp.203-204, 1996. ,
DOI : 10.1016/S0140-6736(05)66157-0
HIV Results in the Frame -Cyclosporine-A, Nature, vol.375, 0198. ,
Increases in CD4 T Lymphocytes with Intermittent Courses of Interleukin-2 in Patients with Human Immunodeficiency Virus Infection ??? A Preliminary Study, New England Journal of Medicine, vol.332, issue.9, pp.567-575, 1995. ,
DOI : 10.1056/NEJM199503023320904
Cutting Edge: Experimentally Induced Immune Activation in Natural Hosts of Simian Immunodeficiency Virus Induces Significant Increases in Viral Replication and CD4+ T Cell Depletion, The Journal of Immunology, vol.181, issue.10, pp.6687-6691, 2008. ,
DOI : 10.4049/jimmunol.181.10.6687
Increased Plasma Human Immunodeficiency Virus Type 1 Burden following Antigenic Challenge with Pneumococcal Vaccine, Journal of Infectious Diseases, vol.174, issue.6, pp.1191-1199, 1996. ,
DOI : 10.1093/infdis/174.6.1191
Hepatitis B Vaccination and Plasma HIV-1 RNA, New England Journal of Medicine, vol.334, issue.19, p.1272, 1996. ,
DOI : 10.1056/NEJM199605093341916
Human Immunodeficiency Virus-Type-1 Replication Can be Increased in Peripheral-Blood of Seropositive Patients After Influenza Vaccination, Blood, vol.86, pp.1082-1089, 1995. ,
Effect of Immunization with a Common Recall Antigen on Viral Expression in Patients Infected with Human Immunodeficiency Virus Type 1, New England Journal of Medicine, vol.334, issue.19, pp.1222-1230, 1996. ,
DOI : 10.1056/NEJM199605093341903
Activation of virus replication after vaccination of HIV-1-infected individuals, Journal of Experimental Medicine, vol.182, issue.6, pp.1727-1737, 1995. ,
DOI : 10.1084/jem.182.6.1727
Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein, Proceedings of the National Academy of Sciences, vol.101, issue.35, pp.13026-13031, 2004. ,
DOI : 10.1073/pnas.0404739101
Roles of Target Cells and Virus-Specific Cellular Immunity in Primary Simian Immunodeficiency Virus Infection, Journal of Virology, vol.78, issue.9, pp.4866-4875, 2004. ,
DOI : 10.1128/JVI.78.9.4866-4875.2004
Mathematical modeling of viral kinetics under immune control during primary HIV-1 infection, Journal of Theoretical Biology, vol.259, issue.4, pp.751-759, 2009. ,
DOI : 10.1016/j.jtbi.2009.04.010
Roles of substrate availability and infection of resting and activated CD4+ T cells in transmission and acute simian immunodeficiency virus infection, Proceedings of the National Academy of Sciences, vol.101, issue.15, pp.5640-5645, 2004. ,
DOI : 10.1073/pnas.0308425101
Vaccine Protection against Simian Immunodeficiency Virus by Recombinant Strains of Herpes Simplex Virus, Journal of Virology, vol.74, issue.17, pp.7745-7754, 2000. ,
DOI : 10.1128/JVI.74.17.7745-7754.2000
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC112303
Investigating Causal Relations by Econometric Models and Cross-Spectral Methods, Econometrica, vol.37, pp.424-438, 1969. ,
DOI : 10.1017/CBO9780511753978.002
CD8+ Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells, CD8+Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells, p.1000747, 2010. ,
DOI : 10.1371/journal.ppat.1000747.s004
In Vivo CD8+ T-Cell Suppression of SIV Viremia Is Not Mediated by CTL Clearance of Productively Infected Cells, PLoS Pathogens, vol.6, issue.1, p.1000748, 2010. ,
DOI : 10.1371/journal.ppat.1000748.s003
Control of HIV-1 infection by soluble factors of the immune response, Nature Reviews Microbiology, vol.80, issue.5, pp.401-413, 2004. ,
DOI : 10.1038/12440
In vivo CD8+ T cell control of immunodeficiency virus infection in humans and macaques, Proceedings of the National Academy of Sciences, vol.104, issue.15, pp.6365-6370, 2007. ,
DOI : 10.1073/pnas.0700666104
Cytotoxic T lymphocytes and viral turnover in HIV type 1 infection, Proceedings of the National Academy of Sciences, vol.93, issue.26, pp.15323-15328, 1996. ,
DOI : 10.1073/pnas.93.26.15323
Persistent immune activation in HIV-1 infection is associated with progression to AIDS, AIDS, vol.17, issue.13, pp.1881-1888, 2003. ,
DOI : 10.1097/00002030-200309050-00006
Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load, Blood, vol.104, issue.4, pp.942-947, 2004. ,
DOI : 10.1182/blood-2003-09-3333
Differential Dynamics of CD4+ and CD8+ T-Lymphocyte Proliferation and Activation in Acute Simian Immunodeficiency Virus Infection, Journal of Virology, vol.74, issue.18, pp.8413-8424, 2000. ,
DOI : 10.1128/JVI.74.18.8413-8424.2000
Direct Relationship between Suppression of Virus-Specific Immunity and Emergence of Cytomegalovirus Disease in Simian AIDS, Journal of Virology, vol.77, issue.10, pp.5749-5758, 2003. ,
DOI : 10.1128/JVI.77.10.5749-5758.2003
Differential CD4+ T-Lymphocyte Apoptosis and Bystander T-Cell Activation in Rhesus Macaques and Sooty Mangabeys during Acute Simian Immunodeficiency Virus Infection, Journal of Virology, vol.83, issue.2, pp.572-583, 2009. ,
DOI : 10.1128/JVI.01715-08
Granger Causality: Basic Theory and Application to Neuroscience, Handbook of Time Series Analysis Wiley-VCH Verlag, pp.437-460, 2007. ,
DOI : 10.1002/9783527609970.ch17
Human B Cells Secrete Granzyme B When Recognizing Viral Antigens in the Context of the Acute Phase Cytokine IL-21, The Journal of Immunology, vol.183, issue.3, pp.1838-1845, 2009. ,
DOI : 10.4049/jimmunol.0901066
B-chronic lymphocytic leukemia cells and other B cells can produce granzyme B and gain cytotoxic potential after interleukin-21-based activation, Blood, vol.108, issue.8, pp.2712-2719, 2006. ,
DOI : 10.1182/blood-2006-03-014001
CD3(+)-T-cell and CD20(+)-B-cell changes predict rapid disease progression after simian-human immunodeficiency virus infection in macaques, J Virol, vol.72, pp.1600-1605, 1998. ,
Kinetics of Lymphocyte Proliferation during Primary Immune Response in Macaques Infected with Pathogenic Simian Immunodeficiency Virus SIVmac251: Preliminary Report of the Effect of Early Antiviral Therapy, Journal of Virology, vol.77, issue.23, pp.12479-12493, 2003. ,
DOI : 10.1128/JVI.77.23.12479-12493.2003
Cytokine Expression, Natural Killer Cell Activation, and Phenotypic Changes in Lymphoid Cells from Rhesus Macaques during Acute Infection with Pathogenic Simian Immunodeficiency Virus, Journal of Virology, vol.74, issue.4, pp.1648-1657, 2000. ,
DOI : 10.1128/JVI.74.4.1648-1657.2000
Bayesian Data Analysis, 2004. ,
Markov Chain Monte Carlo in Practice, 1996. ,
Inference from Iterative Simulation Using Multiple Sequences, Statistical Science, vol.7, issue.4, pp.457-472, 1992. ,
DOI : 10.1214/ss/1177011136
Bayesian measures of model complexity and fit, Journal of the Royal Statistical Society: Series B (Statistical Methodology), vol.93, issue.4, pp.583-616, 2002. ,
DOI : 10.1002/1097-0258(20000915/30)19:17/18<2265::AID-SIM568>3.0.CO;2-6
A Novel Antiviral Intervention Results in More Accurate Assessment of Human Immunodeficiency Virus Type 1 Replication Dynamics and T-Cell Decay In Vivo, Journal of Virology, vol.77, issue.8, pp.5037-5038, 2003. ,
DOI : 10.1128/JVI.77.8.5037-5038.2003
HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time, Science, vol.271, issue.5255, pp.1582-1586, 1996. ,
DOI : 10.1126/science.271.5255.1582