PMID: identifiant
de la référence Pubmed : |
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 (22229863)  |
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| titre : |
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Is Elevated Gastric Tissue NOX2 Associated with Lymphoma of Mucosa-Associated Lymphoid Tissue? |
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| auteur(s) : |
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Emilie Bessède1, 2, Christiane Copie-Bergman3, 4, Philippe Lehours1, 2, Michael Levy5, Karen Leroy4, Maryse Baia3, 4, Audrey Riou6, Francis Mégraud1, 2, Jean-Charles Delchier5, Nathalie Salles ( ) 1, 2, 7 |
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| laboratoire : |
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| résumé : |
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Abstract Helicobacter pylori infection plays a crucial role in the pathogenesis of gastric extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT). However, the host response to this infection is also important in the development of the disease. In particular, NADPH oxidases (NOXs) which generate reactive oxygen species are known to induce cell damage possibly leading to carcinogenesis. We analyze for the first time NOX expression in a series of well characterized gastric MALT lymphoma (GML) patients in comparison with controls. Our observation leads to the hypothesis that NOX2 expression is significantly associated with GML. Antioxid. Redox Signal. 16, 1205-1211. |
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| domaine : |
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Sciences du Vivant/Biochimie, Biologie Moléculaire
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langue du texte
intégral : |
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Anglais |
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| ISSN : |
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1557-7716 |
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| type de publication : |
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Articles dans des revues avec comité de lecture |
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| DOI : |
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10.1089/ars.2011.4494 |
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| journal : |
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| Antioxidants and Redox Signaling (Antioxid Redox Signal) |
| Publisher |
Mary Ann Liebert |
| ISSN |
1523-0864 |
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| Audience : |
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internationale |
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| date de publication : |
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01/06/2012 |
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date de publication
électronique : |
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15/03/2012 |
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| volume : |
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16 |
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| numéro : |
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11 |
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| page, identifiant, ... : |
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1205-11 |
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