JAK-STAT Signaling: From Interferons to Cytokines, Journal of Biological Chemistry, vol.282, issue.28, pp.20059-20063, 2007. ,
DOI : 10.1074/jbc.R700016200
URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.531.3338
Alternative Activation of STAT1 and STAT3 in Response to Interferon-??, Journal of Biological Chemistry, vol.279, issue.40, pp.41679-41685, 2004. ,
DOI : 10.1074/jbc.M406413200
Signal transducers and activators of transcription???from cytokine signalling to cancer biology, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1816, issue.1, pp.38-49, 2011. ,
DOI : 10.1016/j.bbcan.2011.03.003
STAT3 as a central mediator of neoplastic cellular transformation, Cancer Letters, vol.251, issue.2, pp.199-210, 2007. ,
DOI : 10.1016/j.canlet.2006.10.017
Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?, Cell Division, vol.5, issue.1, p.14, 2010. ,
DOI : 10.1016/j.ccr.2009.12.041
Activation of STAT proteins and growth control, BioEssays, vol.9, issue.2, pp.161-169, 2001. ,
DOI : 10.1002/1521-1878(200102)23:2<161::AID-BIES1023>3.0.CO;2-0
Stat proteins and oncogenesis, Journal of Clinical Investigation, vol.109, issue.9, pp.1139-1142, 2002. ,
DOI : 10.1172/JCI0215617
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC150969/pdf
STAT3 as a target for inducing apoptosis in solid and hematological tumors, Cell Research, vol.102, issue.2, pp.254-267, 2008. ,
DOI : 10.1517/14712598.5.8.1085
Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway, Genes & Development, vol.22, issue.4, pp.449-462, 2008. ,
DOI : 10.1101/gad.1606508
Deregulation of a STAT3-Interleukin 8 Signaling Pathway Promotes Human Glioblastoma Cell Proliferation and Invasiveness, Journal of Neuroscience, vol.28, issue.23, pp.285870-5878, 2008. ,
DOI : 10.1523/JNEUROSCI.5385-07.2008
STAT-1: a novel regulator of apoptosis, International Journal of Experimental Pathology, vol.18, issue.6, pp.239-244, 2003. ,
DOI : 10.1111/j.0959-9673.2003.00363.x
STAT1 and pathogens, not a friendly relationship, Biochimie, vol.92, issue.5, pp.425-444, 2010. ,
DOI : 10.1016/j.biochi.2010.02.009
Molecular dynamics simulations of the conformational changes in signal transducers and activators of transcription, Stat1 and Stat3, Journal of Molecular Graphics and Modelling, vol.28, issue.4, pp.347-356, 2009. ,
DOI : 10.1016/j.jmgm.2009.08.013
Phosphorylation???acetylation switch in the regulation of STAT1 signaling, Molecular and Cellular Endocrinology, vol.315, issue.1-2, pp.40-48 ,
DOI : 10.1016/j.mce.2009.10.007
URL : https://hal.archives-ouvertes.fr/hal-00547660
STAT1 acts as a tumor promoter for leukemia development, Cancer Cell, vol.10, issue.1, pp.177-87, 2006. ,
DOI : 10.1016/j.ccr.2006.05.025
Signal transducer and activator of transcription 3 inhibitors: a patent review, Expert Opinion on Therapeutic Patents, vol.9, issue.1, pp.293-300, 2011. ,
DOI : 10.1006/jmbi.1996.0897
Signal Transducer and Activator of Transcription-3, Inflammation, and Cancer, Annals of the New York Academy of Sciences, vol.66, issue.Pt 3, pp.59-76, 2009. ,
DOI : 10.1111/j.1749-6632.2009.04911.x
Targeting STAT3 in cancer: how successful are we?, Expert Opinion on Investigational Drugs, vol.6, issue.1, pp.45-56, 2009. ,
DOI : 10.1186/1476-4598-4-13
Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization, Chemistry & Biology, vol.13, issue.11, pp.1235-1242, 2006. ,
DOI : 10.1016/j.chembiol.2006.09.018
Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor, Journal of Investigative Dermatology, vol.131, issue.1, pp.108-117, 2011. ,
DOI : 10.1038/jid.2010.255
Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth, Proceedings of the National Academy of Sciences, vol.100, issue.7, pp.4138-4143, 2003. ,
DOI : 10.1073/pnas.0534764100
Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide - interference with interferon-??-STAT1-mediated killing, FEBS Journal, vol.270, issue.9, pp.2505-2515, 2009. ,
DOI : 10.1111/j.1742-4658.2009.06975.x
A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-??B, BMC Cell Biology, vol.12, issue.1, p.14, 2011. ,
DOI : 10.1016/j.ccr.2009.02.015
Defective TNF-alpha-induced apoptosis in STAT1-null cells due to low constitutive levels of caspases, Science, issue.5343, pp.2781630-1632, 1997. ,
STAT1: A Modulator of Chemotherapy-induced Apoptosis, Cancer Research, vol.64, issue.22, pp.8357-8364, 2004. ,
DOI : 10.1158/0008-5472.CAN-04-1864
STATs as activators of apoptosis, Trends in Cell Biology, vol.8, issue.3, pp.97-98, 1998. ,
DOI : 10.1016/S0962-8924(98)01233-1
STAT1-induced Apoptosis Is Mediated by Caspases 2, 3, and 7, Journal of Biological Chemistry, vol.279, issue.6, pp.4066-4074, 2004. ,
DOI : 10.1074/jbc.M307774200
STAT-1 Interacts with p53 to Enhance DNA Damage-induced Apoptosis, Journal of Biological Chemistry, vol.279, issue.7, pp.5811-5820, 2004. ,
DOI : 10.1074/jbc.M302637200
Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells, Blood, issue.8, pp.1042475-2483, 2004. ,
IFN-gamma induces apoptosis in ovarian cancer cells in vivo and in vitro, Clin Cancer Res, vol.9, issue.7, pp.2487-2496, 2003. ,
Interferon-gamma inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases-signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway, J Endocrinol, issue.2, pp.199177-189, 2008. ,
IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis, Mol Cancer Ther, vol.2010, issue.95, pp.1274-1285 ,
DOI : 10.1158/1535-7163.mct-09-1169
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925293
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins, Science, vol.264, issue.5164, pp.1415-1421, 1994. ,
DOI : 10.1126/science.8197455
The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter, EMBO J, vol.9, issue.13, pp.4477-4484, 1990. ,
The membrane-distal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation, Blood, vol.87, issue.4, pp.1335-1342, 1996. ,
A STAT protein domain that determines DNA sequence recognition suggests a novel DNA-binding domain., Genes & Development, vol.9, issue.8, pp.984-994, 1995. ,
DOI : 10.1101/gad.9.8.984
Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity., Proceedings of the National Academy of Sciences, vol.92, issue.7, pp.923041-3045, 1995. ,
DOI : 10.1073/pnas.92.7.3041
STAT protein complexes activated by interferon-gamma and gp130 signaling molecules differ in their sequence preferences and transcriptional induction properties, Nucleic Acids Res, issue.16, pp.233283-3289, 1995. ,
DNA Binding Specificity of Different STAT Proteins. COMPARISON OF IN VITRO SPECIFICITY WITH NATURAL TARGET SITES, Journal of Biological Chemistry, vol.276, issue.9, pp.6675-6688, 2001. ,
DOI : 10.1074/jbc.M001748200
One Nucleotide in a ??B Site Can Determine Cofactor Specificity for NF-??B Dimers, Cell, vol.118, issue.4, pp.453-464, 2004. ,
DOI : 10.1016/j.cell.2004.08.007
The structure of an oligo(dA)???oligo(dT) tract and its biological
implications, Nature, vol.330, issue.6145, pp.221-226, 1987. ,
DOI : 10.1038/330221a0
The role of DNA shape in protein???DNA recognition, Nature, vol.117, issue.7268, pp.4611248-1253, 2009. ,
DOI : 10.1038/nature08473
Origins of Specificity in Protein-DNA Recognition, Annual Review of Biochemistry, vol.79, issue.1, pp.233-269, 2010. ,
DOI : 10.1146/annurev-biochem-060408-091030
Crystal Structure of a Tyrosine Phosphorylated STAT-1 Dimer Bound to DNA, Cell, vol.93, issue.5, pp.827-839, 1998. ,
DOI : 10.1016/S0092-8674(00)81443-9
Three-dimensional structure of the Stat3?? homodimer bound to DNA, Nature, vol.64, issue.6689, pp.145-151, 1998. ,
DOI : 10.1038/28101
UCSF Chimera?A visualization system for exploratory research and analysis, Journal of Computational Chemistry, vol.373, issue.13, pp.251605-1612, 2004. ,
DOI : 10.1002/jcc.20084
http://www.molecular-cancer.com/content, Molecular Cancer, vol.111, issue.11, p.1212, 2012. ,
IFN Regulatory Factor-2 Cooperates with STAT1 to Regulate Transporter Associated with Antigen Processing-1 Promoter Activity, The Journal of Immunology, vol.174, issue.7, pp.3948-3958, 2005. ,
DOI : 10.4049/jimmunol.174.7.3948
Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis., Molecular and Cellular Biology, vol.17, issue.9, pp.5328-5337, 1997. ,
DOI : 10.1128/MCB.17.9.5328
Cooperative regulation of Mcl-1 by Janus kinase/stat and phosphatidylinositol 3-kinase contribute to granulocytemacrophage colony-stimulating factor-delayed apoptosis in human neutrophils, J Immunol, issue.12, pp.1667486-7495, 2001. ,
Interferongamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin, Clin Cancer Res, issue.17, pp.96504-6515, 2003. ,
P21Cip1 Is a Critical Mediator of the Cytotoxic Action of Thymidylate Synthase Inhibitors in Colorectal Carcinoma Cells, Cancer Research, vol.64, issue.17, pp.6296-6303, 2004. ,
DOI : 10.1158/0008-5472.CAN-04-0863
DNA bending by an adenine-thymine tract and its role in gene regulation, Proceedings of the National Academy of Sciences, vol.98, issue.15, pp.988490-8495, 2001. ,
DOI : 10.1073/pnas.151247298
Mutational switch of an IL-6 response to an interferon-gamma-like response, Proc Natl Acad Sci, issue.12, pp.998043-8047, 2002. ,
Cutting Edge: Role of STAT1, STAT3, and STAT5 in IFN-???? Responses in T Lymphocytes, The Journal of Immunology, vol.174, issue.2, pp.609-613, 2005. ,
DOI : 10.4049/jimmunol.174.2.609
Stat1 and Stat2 but Not Stat3 Arbitrate Contradictory Growth Signals Elicited by Alpha/Beta Interferon in T Lymphocytes, Molecular and Cellular Biology, vol.25, issue.13, pp.255456-5465, 2005. ,
DOI : 10.1128/MCB.25.13.5456-5465.2005
Ups and downs: The STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling, Seminars in Cell & Developmental Biology, vol.19, issue.4, pp.351-359, 2008. ,
DOI : 10.1016/j.semcdb.2008.06.004
The immediate early genes Fos and Egr1 become STAT1 transcriptional targets in the absence of STAT3, FEBS Letters, vol.120, issue.15, pp.5852455-2460, 2011. ,
DOI : 10.1016/j.febslet.2011.06.020
Signal transducer and activator of transcription 1 (Stat1) maintains basal mRNA expression of pro-survival stat3-target genes in glioma C6 cells, Journal of Cellular Biochemistry, vol.78, issue.12, pp.1123685-3694, 2011. ,
DOI : 10.1002/jcb.23305
DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites, Embo J, issue.20, pp.155616-5626, 1996. ,
Nuclease resistance of an extraordinarily thermostable mini-hairpin DNA fragment, d(GCGAAGC) and its application to in vitro protein synthesis, Nucleic Acids Res, issue.12, pp.222217-2221, 1994. ,
Most compact hairpin-turn structure exerted by a short DNA fragment, d(GCGAAGC) in solution: an extraordinarily stable structure resistant to nucleases and heat, Nucleic Acids Research, vol.22, issue.4, pp.576-582, 1994. ,
DOI : 10.1093/nar/22.4.576
GC), The Journal of Physical Chemistry B, vol.113, issue.19, pp.1136881-6893, 2009. ,
DOI : 10.1021/jp8100656