S. Peock, D. Frost, S. D. Ellis, E. Fineberg, R. Platte et al., Epidemiological study of BRCA1 & BRCA2 mutation carriers (EMBRACE) Douglas F. Easton is the PI of the study. EMBRACE Collaborating Centres are: Coordinating Centre, Deutsches Krebsforschungszentrum (DKFZ) study The DKFZ study was supported by the DKFZ Medical Genetics Services for Wales

R. Davidson, V. Murday, N. Bradshaw, L. Snadden, M. Longmuir et al., South East Thames Regional Genetics Service, Guy's Hospital London: Louise Izatt, Chris Jacobs, Caroline Langman. North West Thames Regional Genetics Service, Harrow: Huw Dorkins, Leicestershire Clinical Genetics Service Yorkshire Regional Genetics Service Gemma Serra-Feliu. Cheshire & Merseyside Clinical Genetics Service Manchester Regional Genetics Service Nottingham Centre for Medical Genetics Northern Clinical Genetics Service

L. Walker, D. Mcleod, D. Halliday, S. Durell, B. S. et al., The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Oxford Regional Genetics Service

G. Evans and F. , Lalloo are supported by an NIHR grant to the Biomedical Research Centre, Manchester. The Investigators at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust are supported by an NIHR grant to the Biomedical Research Centre at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust

:. F. Hogervorst, S. Verhoef, M. Verheus, L. J. Van-'t-veer, F. E. Van-leeuwen et al., Coordinating center: Netherlands Cancer Institute, The Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) HEBON Collaborating Centres: M.J. Ligtenberg, N

H. F. Mourits, I. Vasen, C. U1052, and . Umr5286, The HEBON study is supported by the Dutch Cancer Society grants NKI1998-1854, NKI2004-3088, NKI2007-3756 and the ZonMW grant 91109024 Helsinki Breast Cancer Study (HEBCS) HEBCS acknowledge Drs Kristiina Aittomäki, Kirsimari Aaltonen and Carl Blomqvist and Tuomas Heikkinen and research nurse Irja Erkkilä for their help with the patient data and samples. The HEBCS study has been financially supported by the Helsinki University Central Hospital Research Fund, Academy of Finland (132473), the Finnish Cancer Society, and the Sigrid Juselius Foundation. ICO Contract grant sponsor: Asociación Española Contra el Cáncer, Spanish Health Research Fund; Carlos III Health Institute; Catalan Health Institute and Autonomous Government of Catalonia Contract grant numbers: ISCIIIRETIC RD06/0020, and Population Health Division, Queensland Institute of Medical Research Herston Rd, vol.300, issue.5 6 7 10 11, 1051.

A. Authors-'contributions, D. Kbk, . Wrote, and . Manuscript, KBK performed the statistical analysis ACA supervised the statistical analysis and data management. ACA, GCT and DFE developed the study design. LM and DB are the CIMBA database managers. AL wrote computer programs for the analysis. SH and OMS reviewed, recoded and classified the BRCA1 and BRCA2 mutations in CIMBA, GCT initiated and coordinates CIMBA. PS, JB, XC and YCD performed the genotyping. AJ, SLN, GCT and JS supervised the genotyping of samples

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. Antoniou, 1186/bcr3121 Cite this article as Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers, Breast Cancer Research, vol.14, pp.10-33, 2012.