R. Mclendon, A. Friedman, D. Bigner, V. Meir, E. Brat et al., Comprehensive genomic characterization defines human glioblastoma genes and core pathways, Nature, vol.123, issue.7216, pp.1061-1069, 2008.
DOI : 10.1038/nature07385

D. Parsons, S. Jones, X. Zhang, J. Lin, R. Leary et al., An Integrated Genomic Analysis of Human Glioblastoma Multiforme, Science, vol.321, issue.5897, pp.3211807-1812, 2008.
DOI : 10.1126/science.1164382

F. Ducray, A. Idbaih, A. De-reynies, I. Bieche, J. Thillet et al., Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile, Molecular Cancer, vol.7, issue.1, p.41, 2008.
DOI : 10.1186/1476-4598-7-41

W. Freije, F. Castro-vargas, Z. Fang, S. Horvath, T. Cloughesy et al., Gene Expression Profiling of Gliomas Strongly Predicts Survival, Cancer Research, vol.64, issue.18, pp.6503-6510, 2004.
DOI : 10.1158/0008-5472.CAN-04-0452

A. Idbaih, Y. Marie, C. Lucchesi, G. Pierron, E. Manie et al., BAC array CGH distinguishes mutually exclusive alterations that define clinicogenetic subtypes of gliomas, International Journal of Cancer, vol.65, issue.8, pp.1778-1786, 2008.
DOI : 10.1002/ijc.23270
URL : https://hal.archives-ouvertes.fr/inserm-00310507

Y. Liang, M. Diehn, N. Watson, A. Bollen, K. Aldape et al., Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme, Proceedings of the National Academy of Sciences, vol.102, issue.16, pp.5814-5819, 2005.
DOI : 10.1073/pnas.0402870102

C. Nutt, D. Mani, R. Betensky, P. Tamayo, J. Cairncross et al., Gene expression-based classification of malignant gliomas correlates better with survival than histological classification, Cancer Res, vol.63, pp.1602-1607, 2003.

H. Phillips, S. Kharbanda, R. Chen, W. Forrest, R. Soriano et al., Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis, Cancer Cell, vol.9, issue.3, pp.157-173, 2006.
DOI : 10.1016/j.ccr.2006.02.019

M. Shirahata, K. Iwao-koizumi, S. Saito, N. Ueno, M. Oda et al., Gene Expression-Based Molecular Diagnostic System for Malignant Gliomas Is Superior to Histological Diagnosis, Clinical Cancer Research, vol.13, issue.24, pp.7341-7356, 2007.
DOI : 10.1158/1078-0432.CCR-06-2789

R. Verhaak, K. Hoadley, E. Purdom, V. Wang, Y. Qi et al., Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1, Cancer Cell, vol.17, issue.1, pp.98-110, 2010.
DOI : 10.1016/j.ccr.2009.12.020

P. French, S. Swagemakers, J. Nagel, M. Kouwenhoven, E. Brouwer et al., Gene Expression Profiles Associated with Treatment Response in Oligodendrogliomas, Cancer Research, vol.65, issue.24, pp.11335-11344, 2005.
DOI : 10.1158/0008-5472.CAN-05-1886

A. Murat, E. Migliavacca, T. Gorlia, W. Lambiv, T. Shay et al., Stem Cell???Related ???Self-Renewal??? Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma, Journal of Clinical Oncology, vol.26, issue.18, pp.3015-3024, 2008.
DOI : 10.1200/JCO.2007.15.7164

R. Stupp, W. Mason, M. Van-den-bent, M. Weller, B. Fisher et al., Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma, New England Journal of Medicine, vol.352, issue.10, pp.987-996, 2005.
DOI : 10.1056/NEJMoa043330

D. Macdonald, T. Cascino, S. Schold, . Jr, and J. Cairncross, Response criteria for phase II studies of supratentorial malignant glioma., Journal of Clinical Oncology, vol.8, issue.7, pp.1277-1280, 1990.
DOI : 10.1200/JCO.1990.8.7.1277

E. Criniere, G. Kaloshi, F. Laigle-donadey, J. Lejeune, N. Auger et al., http://www.molecular-cancer.com/content/9/1/234 prognostic impact on glioblastoma is dependent on therapeutic modalities, MGMT Ducray et al. Molecular Cancer J Neurooncol, vol.9, issue.83, pp.234173-179, 2007.

R. Irizarry, B. Bolstad, C. F. Cope, L. Hobbs, B. Speed et al., Summaries of Affymetrix GeneChip probe level data, Nucleic Acids Research, vol.31, issue.4, pp.31-46, 2003.
DOI : 10.1093/nar/gng015

S. Boyault, D. Rickman, A. De-reynies, C. Balabaud, S. Rebouissou et al., Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets, Hepatology, vol.12, issue.1, pp.42-52, 2007.
DOI : 10.1002/hep.21467
URL : https://hal.archives-ouvertes.fr/inserm-00130313

C. Rouveirol, N. Stransky, P. Hupe, P. Rosa, E. Viara et al., Computation of recurrent minimal genomic alterations from array-CGH data, Bioinformatics, vol.22, issue.7, pp.849-856, 2006.
DOI : 10.1093/bioinformatics/btl004

C. Houillier, J. Lejeune, A. Benouaich-amiel, F. Laigle-donadey, E. Criniere et al., Prognostic impact of molecular markers in a series of 220 primary glioblastomas, Cancer, vol.102, issue.10, pp.2218-2223, 2006.
DOI : 10.1002/cncr.21819

J. Nigro, A. Misra, L. Zhang, I. Smirnov, H. Colman et al., Integrated Array-Comparative Genomic Hybridization and Expression Array Profiles Identify Clinically Relevant Molecular Subtypes of Glioblastoma, Cancer Research, vol.65, issue.5, pp.1678-1686, 2005.
DOI : 10.1158/0008-5472.CAN-04-2921

A. Carpentier and Y. Meng, Recent advances in immunotherapy for human glioma, Current Opinion in Oncology, vol.18, issue.6, pp.631-636, 2006.
DOI : 10.1097/01.cco.0000245321.34658.f4

E. Linos, T. Raine, A. Alonso, and D. Michaud, Atopy and Risk of Brain Tumors: A Meta-analysis, JNCI Journal of the National Cancer Institute, vol.99, issue.20, pp.1544-1550, 2007.
DOI : 10.1093/jnci/djm170

J. Schwartzbaum, K. Huang, S. Lawler, B. Ding, J. Yu et al., Allergy and inflammatory transcriptome is predominantly negatively correlated with CD133 expression in glioblastoma, Neuro-Oncology, vol.12, issue.4, pp.320-327, 2010.
DOI : 10.1093/neuonc/nop035

M. Hockel and P. Vaupel, Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects, JNCI Journal of the National Cancer Institute, vol.93, issue.4, pp.266-276, 2001.
DOI : 10.1093/jnci/93.4.266
URL : http://jnci.oxfordjournals.org/cgi/content/short/93/4/266

D. Louis, MOLECULAR PATHOLOGY OF MALIGNANT GLIOMAS, Annual Review of Pathology: Mechanisms of Disease, vol.1, issue.1, pp.97-117, 2006.
DOI : 10.1146/annurev.pathol.1.110304.100043

J. Heddleston, Z. Li, R. Mclendon, A. Hjelmeland, and J. Rich, The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype, Cell Cycle, vol.8, issue.20, pp.3274-3284, 2009.
DOI : 10.4161/cc.8.20.9701

J. Chi, Z. Wang, D. Nuyten, E. Rodriguez, M. Schaner et al., Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers, PLoS Medicine, vol.8, issue.3, p.47, 2006.
DOI : 10.1371/journal.pmed.0030047.st002

A. Spence, M. Muzi, K. Swanson, O. Sullivan, F. Rockhill et al., Regional Hypoxia in Glioblastoma Multiforme Quantified with [18F]Fluoromisonidazole Positron Emission Tomography before Radiotherapy: Correlation with Time to Progression and Survival, Clinical Cancer Research, vol.14, issue.9, pp.2623-2630, 2008.
DOI : 10.1158/1078-0432.CCR-07-4995

S. Evans, K. Judy, I. Dunphy, W. Jenkins, W. Hwang et al., Hypoxia Is Important in the Biology and Aggression of Human Glial Brain Tumors, Clinical Cancer Research, vol.10, issue.24, pp.8177-8184, 2004.
DOI : 10.1158/1078-0432.CCR-04-1081

J. Simon, G. Noel, J. Chiras, K. Hoang-xuan, J. Delattre et al., Radiotherapy and chemotherapy with or without carbogen and nicotinamide in inoperable biopsy-proven glioblastoma multiforme, Radiotherapy and Oncology, vol.67, issue.1, pp.45-51, 2003.
DOI : 10.1016/S0167-8140(03)00007-0

K. Plate, G. Breier, H. Weich, and W. Risau, Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo, Nature, vol.359, issue.6398, pp.845-848, 1992.
DOI : 10.1038/359845a0

D. Shweiki, A. Itin, D. Soffer, and E. Keshet, Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis, Nature, vol.359, issue.6398, pp.843-845, 1992.
DOI : 10.1038/359843a0

R. Jain, E. Di-tomaso, D. Duda, J. Loeffler, A. Sorensen et al., Angiogenesis in brain tumours, Nature Reviews Neuroscience, vol.239, issue.8, pp.610-622, 2007.
DOI : 10.1038/nrn2175

D. Duda, R. Jain, and C. Willett, Antiangiogenics: The Potential Role of Integrating This Novel Treatment Modality With Chemoradiation for Solid Cancers, Journal of Clinical Oncology, vol.25, issue.26, pp.4033-4042, 2007.
DOI : 10.1200/JCO.2007.11.3985

R. Jain, Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy, Science, vol.307, issue.5706, pp.58-62, 2005.
DOI : 10.1126/science.1104819

G. Liu, X. Yuan, Z. Zeng, P. Tunici, H. Ng et al., Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma, Molecular Cancer, vol.5, issue.1, p.67, 2006.
DOI : 10.1186/1476-4598-5-67

A. Salmaggi, A. Boiardi, M. Gelati, A. Russo, C. Calatozzolo et al., Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype, Glia, vol.277, issue.8, pp.850-860, 2006.
DOI : 10.1002/glia.20414

A. Bleau, D. Hambardzumyan, T. Ozawa, E. Fomchenko, J. Huse et al., PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells, Cell Stem Cell, vol.4, issue.3, pp.226-235, 2009.
DOI : 10.1016/j.stem.2009.01.007

H. Ohgaki and P. Kleihues, Genetic Pathways to Primary and Secondary Glioblastoma, The American Journal of Pathology, vol.170, issue.5, pp.1445-1453, 2007.
DOI : 10.2353/ajpath.2007.070011

S. Wemmert, R. Ketter, J. Rahnenfuhrer, N. Beerenwinkel, M. Strowitzki et al., Patients with High-Grade Gliomas Harboring Deletions of Chromosomes 9p and 10q Benefit from Temozolomide Treatment, Neoplasia, vol.7, issue.10, pp.883-893, 2005.
DOI : 10.1593/neo.05307

C. Gomez-manzano, M. Lemoine, M. Hu, J. He, P. Mitlianga et al., Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU, International Journal of Oncology, vol.19, pp.359-365, 2001.
DOI : 10.3892/ijo.19.2.359

S. Hama, Y. Heike, I. Naruse, M. Takahashi, H. Yoshioka et al., Adenovirus???mediated p16 gene transfer prevents drug???induced cell death through G1 arrest in human glioma cells, International Journal of Cancer, vol.77, issue.1, pp.47-54, 1998.
DOI : 10.1002/(SICI)1097-0215(19980703)77:1<47::AID-IJC9>3.3.CO;2-E

M. Weller, J. Rieger, C. Grimmel, V. Meir, E. et al., Predicting chemoresistance in human malignant glioma cells: the role of molecular genetic analyses