Utilizing RNA interference to enhance cancer drug discovery, Nature Reviews Drug Discovery, vol.140, issue.7, pp.556-568, 2007. ,
DOI : 10.1038/nrd2355
Genetic Screening for Signal Transduction in the Era of Network Biology, Cell, vol.128, issue.2, pp.225-231, 2007. ,
DOI : 10.1016/j.cell.2007.01.007
Applications of RNA interference in mammalian systems Annual review of genomics and human genetics, pp.81-108, 2007. ,
High-throughput approaches to dissecting MAPK signaling pathways, Methods, vol.40, issue.3, pp.262-271, 2006. ,
DOI : 10.1016/j.ymeth.2006.05.002
Analysis of cell-based RNAi screens, Genome Biology, vol.7, issue.7, p.66, 2006. ,
DOI : 10.1186/gb-2006-7-7-r66
Increasing the robustness and validity of RNAi screens, Pharmacogenomics, vol.8, issue.8, pp.1037-1049, 2007. ,
DOI : 10.2217/14622416.8.8.1037
Functional profiling of the Saccharomyces cerevisiae genome, Nature, vol.57, issue.6896, pp.387-391, 2002. ,
DOI : 10.1073/pnas.95.25.14863
Genome-Wide RNAi Analysis of Growth and Viability in Drosophila Cells, Science, vol.303, issue.5659, pp.832-835, 2004. ,
DOI : 10.1126/science.1091266
Genome-scale RNAi profiling of cell division in human tissue culture cells, Nature Cell Biology, vol.2005, issue.12, pp.1401-1412, 2007. ,
DOI : 10.1038/ncb1659
The modular nature of genetic diseases, Clinical Genetics, vol.71, pp.1-11, 2006. ,
Multiple knockout analysis of genetic robustness in the yeast metabolic network, Nature Genetics, vol.57, issue.9, pp.993-998, 2006. ,
DOI : 10.1016/S0092-8674(00)00015-5
Lessons from genetics: interpreting complex phenotypes in RNAi screens. Current opinion in cell biology, pp.483-489, 2008. ,
The Gene Ontology (GO) database and informatics resource, Nucleic Acids Res, pp.258-261, 2004. ,
Pathways to the analysis of microarray data, Trends in Biotechnology, vol.23, issue.8, pp.429-435, 2005. ,
DOI : 10.1016/j.tibtech.2005.05.011
Assessing the role of multi-protein complexes and pathways in determining phenotype. Bioconductor Project Working Papers, 2008. ,
Pathway and gene-set activation measurement from mRNA expression data: the tissue distribution of human pathways, Genome Biology, vol.7, issue.10, p.93, 2006. ,
DOI : 10.1186/gb-2006-7-10-r93
A comprehensive pathway map of epidermal growth factor receptor signaling. Molecular systems biology, p.10, 2005. ,
A systems biology approach for pathway level analysis, Genome Research, vol.17, issue.10, pp.1537-1545, 2007. ,
DOI : 10.1101/gr.6202607
Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion, BMC Systems Biology, vol.2, issue.1, p.49, 2008. ,
DOI : 10.1186/1752-0509-2-49
A graph-theoretic approach to testing associations between disparate sources of functional genomics data, Bioinformatics, vol.20, issue.18, pp.3353-3362, 2004. ,
DOI : 10.1093/bioinformatics/bth405
A General Framework for Weighted Gene Co-Expression Network Analysis. Statistical Applications in Genetics and MolecularBiology, 2005. ,
Structural Characterization of the Human Eukaryotic Initiation Factor 3 Protein Complex by Mass Spectrometry, Molecular & Cellular Proteomics, vol.6, issue.7, pp.1135-1146, 2007. ,
DOI : 10.1074/mcp.M600399-MCP200
FAK expression regulation and therapeutic potential Advances in cancer research, pp.45-61, 2008. ,
How complete are current yeast and human protein-interaction networks, Genome Biology, vol.7, issue.120, 2006. ,
CANCER: Enhanced: Addiction to Oncogenes--the Achilles Heal of Cancer, Science, vol.297, issue.5578, pp.63-64, 2002. ,
DOI : 10.1126/science.1073096
Small Interfering RNA Screens Reveal Enhanced Cisplatin Cytotoxicity in Tumor Cells Having both BRCA Network and TP53 Disruptions, Molecular and Cellular Biology, vol.26, issue.24, pp.269377-9386, 2006. ,
DOI : 10.1128/MCB.01229-06
Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells, Proceedings of the National Academy of Sciences, vol.100, issue.10, pp.5789-5794, 2003. ,
DOI : 10.1073/pnas.1031523100
P21-activated kinase is required for mitotic progression and regulates Plk1, Oncogene, vol.20, issue.36, pp.4900-4908, 2008. ,
DOI : 10.1038/onc.2008.131
Identification of essential genes in cultured mammalian cells using small interfering RNAs, J Cell Sci, vol.114, pp.4557-4565, 2001. ,