Basic and clinical aspects of fibrinolysis and thrombolysis, Blood, vol.78, pp.3114-3124, 1991. ,
Tissue-Type Plasminogen Activator: A Multifaceted Modulator of Neurotransmission and Synaptic Plasticity, Neuron, vol.50, issue.5, pp.673-678, 2006. ,
DOI : 10.1016/j.neuron.2006.04.013
Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic, Trends in Neurosciences, vol.32, issue.1, pp.48-55, 2009. ,
DOI : 10.1016/j.tins.2008.09.006
URL : https://hal.archives-ouvertes.fr/inserm-01296642
Plasminogen activator release at the neuronal growth cone, Science, vol.213, issue.4515, pp.1532-1534, 1981. ,
DOI : 10.1126/science.7197054
Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene, Proceedings of the National Academy of Sciences, vol.96, issue.24, pp.14118-14123, 1999. ,
DOI : 10.1073/pnas.96.24.14118
Permissive proteolytic activity for visual cortical plasticity, Proceedings of the National Academy of Sciences, vol.99, issue.11, pp.7717-7721, 2002. ,
DOI : 10.1073/pnas.102088899
Tissue Plasminogen Activator Contributes to the Late Phase of LTP and to Synaptic Growth in the Hippocampal Mossy Fiber Pathway, Neuron, vol.21, issue.4, pp.813-825, 1998. ,
DOI : 10.1016/S0896-6273(00)80597-8
Tissue plasminogen activator controls multiple forms of synaptic plasticity and memory, European Journal of Neuroscience, vol.54, issue.3, pp.1002-1012, 2000. ,
DOI : 10.1046/j.1460-9568.2000.00991.x
Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator, Nature, vol.377, issue.6547, pp.340-344, 1995. ,
DOI : 10.1038/377340a0
The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling, Nat Med, vol.7, pp.59-64, 2001. ,
Tissue-type plasminogen activator rescues neurones from serum deprivation-induced apoptosis through a mechanism independent of its proteolytic activity, Journal of Neurochemistry, vol.20, issue.5, pp.1458-1464, 2006. ,
DOI : 10.1016/j.expneurol.2004.05.032
URL : https://hal.archives-ouvertes.fr/inserm-01296667
Thrombolysis With Tissue Plasminogen Activator Alters Adhesion Molecule Expression in the Ischemic Rat Brain ?? Editorial Comment, Stroke, vol.30, issue.3, pp.624-629, 1999. ,
DOI : 10.1161/01.STR.30.3.624
Tissue plasminogen activator prevents white matter damage following stroke, The Journal of Experimental Medicine, vol.122, issue.6, pp.1229-1242, 2011. ,
DOI : 10.1111/j.1471-4159.2007.04866.x
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173251
Tissue plasminogen activator and NMDA receptor cleavage, Nature Medicine, vol.9, issue.4, pp.371-372, 2003. ,
DOI : 10.1038/nm0403-371
Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function, Journal of Neurochemistry, vol.20, pp.1091-1101, 2008. ,
DOI : 10.1111/j.1471-4159.2008.05687.x
Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits, Nature, vol.307, issue.6873, pp.793-798, 2002. ,
DOI : 10.1038/nature715
New Insights into the Not-So-New NR3 Subunits of N-Methyl-D-aspartate Receptor: Localization, Structure, and Function, Molecular Pharmacology, vol.78, issue.1, pp.1-11, 2010. ,
DOI : 10.1124/mol.110.064006
Role of Distinct NMDA Receptor Subtypes at Central Synapses, Science Signaling, vol.2004, issue.255, p.16, 2004. ,
DOI : 10.1126/stke.2552004re16
Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways, Nature Neuroscience, vol.5, pp.405-414, 2002. ,
DOI : 10.1038/nn835
Compartmentalized NMDA receptor signalling to survival and death, The Journal of Physiology, vol.53, issue.2, pp.381-387, 2007. ,
DOI : 10.1113/jphysiol.2007.138875
NMDA Receptor Subunits Have Differential Roles in Mediating Excitotoxic Neuronal Death Both In Vitro and In Vivo, Journal of Neuroscience, vol.27, issue.11, pp.2846-2857, 2007. ,
DOI : 10.1523/JNEUROSCI.0116-07.2007
NMDA receptor function: subunit composition versus spatial distribution, Cell and Tissue Research, vol.27, issue.Suppl 1, pp.439-446, 2006. ,
DOI : 10.1007/s00441-006-0273-6
NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity, Cell Death and Differentiation, vol.23, issue.5, pp.860-871, 2010. ,
DOI : 10.1111/j.1471-4159.2006.03982.x
Structure-activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid, British Journal of Pharmacology, vol.707, issue.3, pp.508-516, 2004. ,
DOI : 10.1038/sj.bjp.0705644
-Substituted Piperazine-2,3-dicarboxylic Acid Derivatives Acting as NMDA Receptor Antagonists, Journal of Medicinal Chemistry, vol.48, issue.7, pp.2627-2637, 2005. ,
DOI : 10.1021/jm0492498
URL : https://hal.archives-ouvertes.fr/hal-01259996
N-Methyl-D-aspartate (NMDA) Receptor NR2 Subunit Selectivity of a Series of Novel Piperazine-2,3-dicarboxylate Derivatives: Preferential Blockade of Extrasynaptic NMDA Receptors in the Rat Hippocampal CA3-CA1 Synapse, Journal of Pharmacology and Experimental Therapeutics, vol.331, issue.2, pp.618-626, 2009. ,
DOI : 10.1124/jpet.109.156752
oocytes, The Journal of Physiology, vol.117, issue.1, pp.211-225, 2008. ,
DOI : 10.1113/jphysiol.2007.143164
Mg2+ Imparts NMDA Receptor Subtype Selectivity to the Alzheimer's Drug Memantine, Journal of Neuroscience, vol.29, issue.9, pp.2774-2779, 2009. ,
DOI : 10.1523/JNEUROSCI.3703-08.2009
Tissue-Type Plasminogen Activator Crosses the Intact Blood-Brain Barrier by Low-Density Lipoprotein Receptor-Related Protein-Mediated Transcytosis, Circulation, vol.111, issue.17, pp.2241-2250, 2005. ,
DOI : 10.1161/01.CIR.0000163542.48611.A2
URL : https://hal.archives-ouvertes.fr/hal-00542121
Mouse Model of In Situ Thromboembolic Stroke and Reperfusion, Stroke, vol.38, issue.10, pp.2771-2778, 2007. ,
DOI : 10.1161/STROKEAHA.107.487520
Functional Occurrence of the Interaction of Tissue Plasminogen Activator With the NR1 Subunit of N-Methyl-D-Aspartate Receptors During Stroke, Stroke, vol.41, issue.12, pp.2950-2955, 2010. ,
DOI : 10.1161/STROKEAHA.110.592360
Antibodies Preventing the Interaction of Tissue-Type Plasminogen Activator With N-Methyl-D-Aspartate Receptors Reduce Stroke Damages and Extend the Therapeutic Window of Thrombolysis, Stroke, vol.42, issue.8, pp.2315-2337, 2011. ,
DOI : 10.1161/STROKEAHA.110.606293
http://www.molecularneurodegeneration.com/content, Molecular Neurodegeneration, vol.61, issue.6, p.6868, 2011. ,
Synaptic and Extrasynaptic NMDA Receptor NR2 Subunits in Cultured Hippocampal Neurons, Journal of Neurophysiology, vol.95, issue.3, pp.1727-1734, 2006. ,
DOI : 10.1152/jn.00771.2005
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders, Nature Reviews Neuroscience, vol.39, issue.10, pp.682-696, 2010. ,
DOI : 10.1038/nrn2911
Distinct NMDA receptor subpopulations contribute to long-term potentiation and long-term depression induction, J Neurosci, vol.20, p.81, 2000. ,
Extrasynaptic NR2B and NR2D subunits of NMDA receptors shape ???superslow??? afterburst EPSC in rat hippocampus, The Journal of Physiology, vol.16, issue.2, pp.451-463, 2004. ,
DOI : 10.1113/jphysiol.2004.063792
Extrasynaptic NR2D-Containing NMDARs Are Recruited to the Synapse during LTP of NMDAR-EPSCs, Journal of Neuroscience, vol.28, issue.45, pp.11685-11694, 2008. ,
DOI : 10.1523/JNEUROSCI.3035-08.2008
NMDA NR2 receptors participate in CCK-induced reduction of food intake and hindbrain neuronal activation, Brain Research, vol.1266, pp.37-44, 2009. ,
DOI : 10.1016/j.brainres.2009.02.003
Differential expression of N-methyl-d-aspartate receptor NR2 isoforms in Alzheimer's disease, Journal of Neurochemistry, vol.90, issue.4, pp.913-919, 2004. ,
DOI : 10.1111/j.1471-4159.2004.02548.x
Spotlight on Memantine in Moderate to Severe Alzheimer??s Disease???, Drugs & Aging, vol.23, issue.5, pp.177-179, 2010. ,
DOI : 10.2165/11204670-000000000-00000
Intracisternal Administration of NR2 Subunit Antagonists Attenuates the Nociceptive Behavior and p-p38 MAPK Expression Produced by Compression of the Trigeminal Nerve Root, Molecular Pain, vol.12, p.46, 2011. ,
DOI : 10.3171/jns.1999.90.1.0001
Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke, Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke, pp.1317-1329, 2008. ,
DOI : 10.1056/NEJMoa0804656
Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons, Brain Research, vol.1035, issue.1, pp.24-31, 2005. ,
DOI : 10.1016/j.brainres.2004.11.054