C. Staples and J. Davis, An examination of the physical properties, fate, ecotoxicity and potential environmental risks for a series of propylene glycol ethers, Chemosphere, vol.49, issue.1, pp.61-73, 2002.
DOI : 10.1016/S0045-6535(02)00176-5

R. Chapin, J. Adams, K. Boekelheide, L. Gray, . Jr et al., NTP-CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A, Birth Defects Research Part B: Developmental and Reproductive Toxicology, vol.146, issue.Suppl, pp.157-395, 2008.
DOI : 10.1002/bdrb.20147

M. Focazio, D. Kolpin, K. Barnes, E. Furlong, M. Meyer et al., A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States ??? II) Untreated drinking water sources, Science of The Total Environment, vol.402, issue.2-3, pp.201-216, 2008.
DOI : 10.1016/j.scitotenv.2008.02.021

A. Belfroid, M. Van-velzen, B. Van-der-horst, and D. Vethaak, Occurrence of bisphenol A in surface water and uptake in fish: evaluation of field measurements, Chemosphere, vol.49, issue.1, pp.97-103, 2002.
DOI : 10.1016/S0045-6535(02)00157-1

D. Kolpin, E. Furlong, M. Meyer, E. Thurman, S. Zaugg et al., Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance, Environ Sci Technol, issue.6, pp.361202-1211, 2002.

H. Kuch and K. Ballschmiter, Determination of Endocrine-Disrupting Phenolic Compounds and Estrogens in Surface and Drinking Water by HRGC???(NCI)???MS in the Picogram per Liter Range, Environmental Science & Technology, vol.35, issue.15, pp.353201-3206, 2001.
DOI : 10.1021/es010034m

C. Basheer, H. Lee, and K. Tan, Endocrine disrupting alkylphenols and bisphenol-A in coastal waters and supermarket seafood from Singapore, Marine Pollution Bulletin, vol.48, issue.11-12, pp.11-121161, 2004.
DOI : 10.1016/j.marpolbul.2004.04.009

A. Calafat, Z. Kuklenyik, J. Reidy, S. Caudill, J. Ekong et al., Urinary Concentrations of Bisphenol A and 4-Nonylphenol in a Human Reference Population, Environmental Health Perspectives, vol.113, issue.4, pp.391-395, 2005.
DOI : 10.1289/ehp.7534

T. Takeuchi and O. Tsutsumi, Serum Bisphenol A Concentrations Showed Gender Differences, Possibly Linked to Androgen Levels, Biochemical and Biophysical Research Communications, vol.291, issue.1, pp.76-78, 2002.
DOI : 10.1006/bbrc.2002.6407

Y. Ikezuki, O. Tsutsumi, Y. Takai, Y. Kamei, and Y. Taketani, Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure, Human Reproduction, vol.17, issue.11, pp.2839-2841, 2002.
DOI : 10.1093/humrep/17.11.2839

G. Schonfelder, B. Flick, E. Mayr, C. Talsness, M. Paul et al., In Utero Exposure to Low Doses of Bisphenol A Lead to Long-term Deleterious Effects in the Vagina, Neoplasia, vol.4, issue.2, pp.98-102, 2002.
DOI : 10.1038/sj.neo.7900212

Y. Sun, M. Irie, N. Kishikawa, M. Wada, N. Kuroda et al., Determination of bisphenol A in human breast milk by HPLC with column-switching and fluorescence detection, Biomed Chromatogr, issue.8, pp.18501-507, 2004.

M. Chen, M. Ike, and M. Fujita, Acute toxicity, mutagenicity, and estrogenicity of bisphenol-A and other bisphenols, Environmental Toxicology, vol.36, issue.1, pp.80-86, 2002.
DOI : 10.1002/tox.10035

P. Perez, R. Pulgar, F. Olea-serrano, M. Villalobos, A. Rivas et al., The estrogenicity of bisphenol A-related diphenylalkanes with various substituents at the central carbon and the hydroxy groups, Environmental Health Perspectives, vol.106, issue.3, pp.167-174, 1998.
DOI : 10.1289/ehp.98106167

K. Satoh, K. Ohyama, N. Aoki, M. Iida, and F. Nagai, Study on anti-androgenic effects of bisphenol a diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE) and their derivatives using cells stably transfected with human androgen receptor, AR-EcoScreen, Food and Chemical Toxicology, vol.42, issue.6, pp.42983-993, 2004.
DOI : 10.1016/j.fct.2004.02.011

R. Waring and R. Harris, Endocrine disrupters: A human risk?, Molecular and Cellular Endocrinology, vol.244, issue.1-2, pp.2-9, 2005.
DOI : 10.1016/j.mce.2005.02.007

D. Crain, M. Eriksen, T. Iguchi, S. Jobling, H. Laufer et al., An ecological assessment of bisphenol-A: Evidence from comparative biology, Reproductive Toxicology, vol.24, issue.2, pp.225-239, 2007.
DOI : 10.1016/j.reprotox.2007.05.008

M. Maffini, B. Rubin, C. Sonnenschein, and A. Soto, Endocrine disruptors and reproductive health: The case of bisphenol-A, Molecular and Cellular Endocrinology, vol.254, issue.255, pp.254-255179, 2006.
DOI : 10.1016/j.mce.2006.04.033

Y. Wetherill, B. Akingbemi, J. Kanno, J. Mclachlan, A. Nadal et al., In vitro molecular mechanisms of bisphenol A action, Reproductive Toxicology, vol.24, issue.2, pp.178-198, 2007.
DOI : 10.1016/j.reprotox.2007.05.010

G. Kuiper, P. Shughrue, I. Merchenthaler, and J. Gustafsson, The Estrogen Receptor ?? Subtype: A Novel Mediator of Estrogen Action in Neuroendocrine Systems, Frontiers in Neuroendocrinology, vol.19, issue.4, pp.253-286, 1998.
DOI : 10.1006/frne.1998.0170

W. Pennie, T. Aldridge, and A. Brooks, Differential activation by xenoestrogens of ER alpha and ER beta when linked to different response elements, Journal of Endocrinology, vol.158, issue.3, pp.11-14, 1998.
DOI : 10.1677/joe.0.158R011

L. Bjornstrom and M. Sjoberg, Mechanisms of Estrogen Receptor Signaling: Convergence of Genomic and Nongenomic Actions on Target Genes, Molecular Endocrinology, vol.19, issue.4, pp.833-842, 2005.
DOI : 10.1210/me.2004-0486

H. Hiroi, O. Tsutsumi, M. Momoeda, Y. Takai, Y. Osuga et al., Differential Interactions of Bisphenol A and 17.BETA.-estradiol with Estrogen Receptor .ALPHA.(ER.ALPHA.) and ER.BETA.., Endocrine Journal, vol.46, issue.6, pp.773-778, 1999.
DOI : 10.1507/endocrj.46.773

C. Richter, J. Taylor, R. Ruhlen, and W. Welshons, Estradiol and Bisphenol A Stimulate Androgen Receptor and Estrogen Receptor Gene Expression in Fetal Mouse Prostate Mesenchyme Cells, Environmental Health Perspectives, vol.115, issue.6, pp.902-908, 2007.
DOI : 10.1289/ehp.9804

A. Wozniak, N. Bulayeva, and C. Watson, Xenoestrogens at Picomolar to Nanomolar Concentrations Trigger Membrane Estrogen Receptor-?????Mediated Ca2+ Fluxes and Prolactin Release in GH3/B6 Pituitary Tumor Cells, Environmental Health Perspectives, vol.113, issue.4, pp.431-439, 2005.
DOI : 10.1289/ehp.7505

A. Zsarnovszky, H. Le, H. Wang, and S. Belcher, Ontogeny of rapid estrogenmediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol A, Endocrinology, issue.12, pp.1465388-5396, 2005.

K. Moriyama, T. Tagami, T. Akamizu, T. Usui, M. Saijo et al., Thyroid Hormone Action Is Disrupted by Bisphenol A as an Antagonist, The Journal of Clinical Endocrinology & Metabolism, vol.87, issue.11, pp.5185-5190, 2002.
DOI : 10.1210/jc.2002-020209

R. Zoeller, Environmental chemicals as thyroid hormone analogues: New studies indicate that thyroid hormone receptors are targets of industrial chemicals?, Molecular and Cellular Endocrinology, vol.242, issue.1-2, pp.10-15, 2005.
DOI : 10.1016/j.mce.2005.07.006

R. Zoeller, R. Bansal, and C. Parris, , Increases Serum Thyroxine, and Alters RC3/Neurogranin Expression in the Developing Rat Brain, Endocrinology, vol.146, issue.2, pp.607-612, 2005.
DOI : 10.1210/en.2004-1018

S. Iwamuro, M. Yamada, M. Kato, and S. Kikuyama, Effects of bisphenol A on thyroid hormone-dependent up-regulation of thyroid hormone receptor alpha and beta and down-regulation of retinoid X receptor gamma in Xenopus tail culture, Life Sci, issue.23, pp.792165-2171, 2006.

J. Fini, L. Mevel, S. Turque, N. Palmier, K. Zalko et al., An In Vivo Multiwell-Based Fluorescent Screen for Monitoring Vertebrate Thyroid Hormone Disruption, Environmental Science & Technology, vol.41, issue.16, pp.415908-5914, 2007.
DOI : 10.1021/es0704129
URL : https://hal.archives-ouvertes.fr/hal-00179367

Z. Duan, L. Zhu, L. Zhu, Y. Kun, and X. Zhu, Individual and joint toxic effects of pentachlorophenol and bisphenol A on the development of zebrafish (Danio rerio) embryo, Ecotoxicology and Environmental Safety, vol.71, issue.3, pp.71774-780, 2008.
DOI : 10.1016/j.ecoenv.2008.01.021

S. Pastva, S. Villalobos, K. Kannan, and J. Giesy, Morphological effects of Bisphenol-A on the early life stages of medaka (Oryzias latipes), Chemosphere, vol.45, issue.4-5
DOI : 10.1016/S0045-6535(01)00018-2

K. Baba, K. Okada, T. Kinoshita, and S. Imaoka, Bisphenol A Disrupts Notch Signaling by Inhibiting Gamma-Secretase Activity and Causes Eye Dysplasia of Xenopus laevis, Toxicological Sciences, vol.108, issue.2, pp.344-355, 2009.
DOI : 10.1093/toxsci/kfp025

R. Heimeier, B. Das, D. Buchholz, and Y. Shi, The Xenoestrogen Bisphenol A Inhibits Postembryonic Vertebrate Development by Antagonizing Gene Regulation by Thyroid Hormone, Endocrinology, vol.150, issue.6, pp.2964-2973, 2009.
DOI : 10.1210/en.2008-1503

S. Imaoka, T. Mori, and T. Kinoshita, Bisphenol A Causes Malformation of the Head Region in Embryos of Xenopus laevis and Decreases the Expression of the ESR-1 Gene Mediated by Notch Signaling, Biological & Pharmaceutical Bulletin, vol.30, issue.2, pp.371-374, 2007.
DOI : 10.1248/bpb.30.371

C. Kimmel, W. Ballard, S. Kimmel, B. Ullmann, and T. Schilling, Stages of embryonic development of the zebrafish, Developmental Dynamics, vol.102, issue.3, pp.253-310, 1995.
DOI : 10.1002/aja.1002030302

D. Zalko, A. Soto, L. Dolo, C. Dorio, E. Rathahao et al., Biotransformations of Bisphenol A in a Mammalian Model: Answers and New Questions Raised by Low-Dose Metabolic Fate Studies in Pregnant CD1 Mice, Environmental Health Perspectives, vol.111, issue.3, pp.309-319, 2003.
DOI : 10.1289/ehp.5603

N. Cabaton, D. Zalko, E. Rathahao, C. Canlet, G. Delous et al., Biotransformation of bisphenol F by human and rat liver subcellular fractions, Toxicology in Vitro, vol.22, issue.7, pp.221697-1704, 2008.
DOI : 10.1016/j.tiv.2008.07.004
URL : https://hal.archives-ouvertes.fr/hal-01173776

P. Nieuwkoop and J. Faber, Normal table of Xenopus laevis, 1994.

C. Thisse, B. Thisse, T. Schilling, and J. Postlethwait, Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos, Development, vol.119, issue.4, pp.1203-1215, 1993.

A. Avanesov, R. Dahm, W. Sewell, and J. Malicki, Mutations that affect the survival of selected amacrine cell subpopulations define a new class of genetic defects in the vertebrate retina, Developmental Biology, vol.285, issue.1, pp.138-155, 2005.
DOI : 10.1016/j.ydbio.2005.06.009

H. Escriva, S. Bertrand, P. Germain, M. Robinson-rechavi, M. Umbhauer et al., Neofunctionalization in Vertebrates: The Example of Retinoic Acid Receptors, PLoS Genetics, vol.30, issue.7, p.102, 2006.
DOI : 10.1371/journal.pgen.0020102.sg005
URL : https://hal.archives-ouvertes.fr/hal-00187905

J. Legler, L. Zeinstra, F. Schuitemaker, P. Lanser, J. Bogerd et al., Van der Burg B: Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity, Environ Sci Technol, issue.20, pp.364410-4415, 2002.

I. Hughes, I. Thalmann, R. Thalmann, and D. Ornitz, Mixing model systems: Using zebrafish and mouse inner ear mutants and other organ systems to unravel the mystery of otoconial development, Brain Research, vol.1091, issue.1, pp.109158-74, 2006.
DOI : 10.1016/j.brainres.2006.01.074

S. Ramakrishnan and N. Wayne, Impact of bisphenol-A on early embryonic development and reproductive maturation, Reproductive Toxicology, vol.25, issue.2, pp.177-183, 2008.
DOI : 10.1016/j.reprotox.2007.11.002

T. Whitfield, M. Granato, F. Van-eeden, U. Schach, M. Brand et al., Mutations affecting development of the zebrafish inner ear and lateral line, pp.241-254, 1996.

B. Riley, C. Zhu, C. Janetopoulos, and K. Aufderheide, A Critical Period of Ear Development Controlled by Distinct Populations of Ciliated Cells in the Zebrafish, Developmental Biology, vol.191, issue.2, pp.191-201, 1997.
DOI : 10.1006/dbio.1997.8736

J. Colantonio, J. Vermot, D. Wu, A. Langenbacher, S. Fraser et al., The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear, Nature, vol.154, issue.7226, pp.457205-209, 2009.
DOI : 10.1038/nature07520

S. Hans and M. Westerfield, Changes in retinoic acid signaling alter otic patterning, Development, vol.134, issue.13, pp.2449-2458, 2007.
DOI : 10.1242/dev.000448

K. Solomon, S. Kwak, and A. Fritz, Genetic interactions underlying otic placode induction and formation, Developmental Dynamics, vol.113, issue.3, pp.419-433, 2004.
DOI : 10.1002/dvdy.20067

K. Hammond, H. Loynes, A. Folarin, J. Smith, and T. Whitfield, Hedgehog signalling is required for correct anteroposterior patterning of the zebrafish otic vesicle, Development, vol.130, issue.7, pp.1403-1417, 2003.
DOI : 10.1242/dev.00360

J. Petko, B. Millimaki, V. Canfield, B. Riley, and R. Levenson, Otoc1: A novel otoconin-90 ortholog required for otolith mineralization in zebrafish, Developmental Neurobiology, vol.304, issue.2, pp.209-222, 2008.
DOI : 10.1002/dneu.20587

B. Blasiole, V. Canfield, M. Vollrath, D. Huss, M. Mohideen et al., Separate Na,K-ATPase genes are required for otolith formation and semicircular canal development in zebrafish, Developmental Biology, vol.294, issue.1, pp.148-160, 2006.
DOI : 10.1016/j.ydbio.2006.02.034

E. Busch-nentwich, C. Sollner, H. Roehl, and T. Nicolson, The deafness gene dfna5 is crucial for ugdh expression and HA production in the developing ear in zebrafish, Development, vol.131, issue.4, pp.943-951, 2004.
DOI : 10.1242/dev.00961

S. Pittlik, S. Domingues, A. Meyer, and G. Begemann, Expression of zebrafish aldh1a3 (raldh3) and absence of aldh1a1 in teleosts, Gene Expression Patterns, vol.8, issue.3, pp.141-147, 2008.
DOI : 10.1016/j.gep.2007.11.003

I. Meltser, Y. Tahera, E. Simpson, M. Hultcrantz, K. Charitidi et al., Estrogen receptor ?? protects against acoustic trauma in mice, Journal of Clinical Investigation, vol.118, issue.4, pp.1563-1570, 2008.
DOI : 10.1172/JCI32796

J. Sisneros, P. Forlano, D. Deitcher, and A. Bass, Steroid-Dependent Auditory Plasticity Leads to Adaptive Coupling of Sender and Receiver, Science, vol.305, issue.5682, pp.305404-407, 2004.
DOI : 10.1126/science.1097218

P. Bardet, B. Horard, M. Robinson-rechavi, V. Laudet, and J. Vanacker, Characterization of oestrogen receptors in zebrafish (Danio rerio), Journal of Molecular Endocrinology, vol.28, issue.3, pp.153-163, 2002.
DOI : 10.1677/jme.0.0280153

A. Menuet, E. Pellegrini, I. Anglade, O. Blaise, V. Laudet et al., Molecular Characterization of Three Estrogen Receptor Forms in Zebrafish: Binding Characteristics, Transactivation Properties, and Tissue Distributions1, Biology of Reproduction, vol.66, issue.6, pp.661881-1892, 2002.
DOI : 10.1095/biolreprod66.6.1881

S. Bertrand, B. Thisse, R. Tavares, L. Sachs, A. Chaumot et al., Unexpected Novel Relational Links Uncovered by Extensive Developmental Profiling of Nuclear Receptor Expression, PLoS Genetics, vol.41, issue.11, p.188, 2007.
DOI : 10.1371/journal.pgen.0030188.st005
URL : https://hal.archives-ouvertes.fr/hal-00207389

S. Sassi-messai, Y. Gibert, L. Bernard, S. Nishio, F. Lagneau et al., The Phytoestrogen Genistein Affects Zebrafish Development through Two Different Pathways, PLoS ONE, vol.32, issue.103, p.4935, 2009.
DOI : 10.1371/journal.pone.0004935.s002

E. Abel, M. Boers, C. Pazos-moura, E. Moura, H. Kaulbach et al., Divergent roles for thyroid hormone receptor ?? isoforms in the endocrine axis and auditory system, Journal of Clinical Investigation, vol.104, issue.3, pp.291-300, 1999.
DOI : 10.1172/JCI6397

A. Rusch, L. Erway, D. Oliver, B. Vennstrom, and D. Forrest, Thyroid hormone receptor beta-dependent expression of a potassium conductance in inner hair cells at the onset of hearing, Proc Natl Acad Sci, issue.26, pp.9515758-15762, 1998.

M. Dubois, G. Sebillot, A. Kuiper, G. Verhoelst, C. Darras et al., during Early Embryogenesis, Endocrinology, vol.147, issue.10, pp.4941-4949, 2006.
DOI : 10.1210/en.2006-0609
URL : https://hal.archives-ouvertes.fr/hal-00093438

B. Blasiole, A. Degrave, V. Canfield, W. Boehmler, C. Thisse et al., Differential expression of Na,K-ATPase ? and ? subunit genes in the developing zebrafish inner ear, Developmental Dynamics, vol.223, issue.3, pp.386-392, 2003.
DOI : 10.1002/dvdy.10391

C. Haddon and J. Lewis, Early ear development in the embryo of the Zebrafish,Danio rerio, The Journal of Comparative Neurology, vol.64, issue.1, pp.113-128, 1996.
DOI : 10.1002/(SICI)1096-9861(19960129)365:1<113::AID-CNE9>3.0.CO;2-6

T. Nicolson, The Genetics of Hearing and Balance in Zebrafish, Annual Review of Genetics, vol.39, issue.1, pp.9-22, 2005.
DOI : 10.1146/annurev.genet.39.073003.105049

R. Hawkins, S. Bashiardes, K. Powder, S. Sajan, V. Bhonagiri et al., Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia, PLoS ONE, vol.(in press), issue.6, p.525, 2007.
DOI : 10.1371/journal.pone.0000525.s022

U. Kausch, M. Alberti, S. Haindl, J. Budczies, and B. Hock, Biomarkers for exposure to estrogenic compounds: Gene expression analysis in zebrafish (Danio rerio), Environmental Toxicology, vol.33, issue.1, pp.15-24, 2008.
DOI : 10.1002/tox.20306

R. Thalmann, E. Ignatova, B. Kachar, and D. Ornitz, Development and Maintenance of Otoconia, Annals of the New York Academy of Sciences, vol.40, issue.31, pp.162-178, 2001.
DOI : 10.1111/j.1749-6632.2001.tb03743.x

G. Markov, M. Paris, S. Bertrand, and V. Laudet, The evolution of the ligand/receptor couple: A long road from comparative endocrinology to comparative genomics, Molecular and Cellular Endocrinology, vol.293, issue.1-2, pp.5-16, 2008.
DOI : 10.1016/j.mce.2008.06.011
URL : https://hal.archives-ouvertes.fr/hal-00532041

M. Bever, Y. Jean, and D. Fekete, Three-dimensional morphology of inner ear development inXenopus laevis, Developmental Dynamics, vol.84, issue.3, pp.422-430, 2003.
DOI : 10.1002/dvdy.10316