Essential thrombocythemia and pregnancy.

Abstract : Essential thrombocythaemia (ET) is an acquired myeloproliferative neoplasm, characterised by persistent thrombocytosis and a tendency for either thrombosis or haemorrhage. Among myeloproliferative neoplasms, ET is the most prevalent in young women, which constitute a special group due to their childbearing potential. An increased risk of fetal and maternal complications has been demonstrated in patients with ET. The most common pregnancy-related complication is spontaneous abortion during the first trimester. Recurrent abortion, fetal growth restriction, stillbirth and placental abruption are less frequent. Maternal complications are relatively rare and essentially represented by thromboembolic and bleeding events. Here we summarize the literature describing pregnancy and its outcome in patients with ET and discuss some recommendations for the management of pregnancy.
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Article dans une revue
European Journal of Obstetrics and Gynecology and Reproductive Biology, Elsevier, 2011, epub ahead of print. 〈10.1016/j.ejogrb.2011.04.040〉
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http://www.hal.inserm.fr/inserm-00615502
Contributeur : Marie Francoise Simon <>
Soumis le : vendredi 19 août 2011 - 15:38:21
Dernière modification le : jeudi 9 novembre 2017 - 09:38:02

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Marie-Cécile Valera, Olivier Parant, Christophe Vayssiere, Jean-François Arnal, Bernard Payrastre. Essential thrombocythemia and pregnancy.. European Journal of Obstetrics and Gynecology and Reproductive Biology, Elsevier, 2011, epub ahead of print. 〈10.1016/j.ejogrb.2011.04.040〉. 〈inserm-00615502〉

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