Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: prevention by HDLs.

Abstract : Oxidized LDLs (oxLDLs) induce various cellular dysfunctions potentially implicated in the pathogenesis of atherosclerosis. For instance, toxic concentrations of oxLDLs trigger ER stress, autophagy and apoptosis. High-density lipoproteins (HDLs) counteract several adverse biological effects triggered by oxLDLs. Our recent study reveals that HDLs inhibit the activation of ER stress and of autophagy induced by oxLDLs.
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Article dans une revue
Autophagy, Taylor & Francis, 2011, 7 (5), pp.541-3
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http://www.hal.inserm.fr/inserm-00615490
Contributeur : Marie Francoise Simon <>
Soumis le : vendredi 19 août 2011 - 14:53:46
Dernière modification le : jeudi 25 août 2011 - 12:14:26

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  • HAL Id : inserm-00615490, version 1
  • PUBMED : 21412049

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Carole Muller, Robert Salvayre, Anne Nègre-Salvayre, Cécile Vindis. Oxidized LDLs trigger endoplasmic reticulum stress and autophagy: prevention by HDLs.. Autophagy, Taylor & Francis, 2011, 7 (5), pp.541-3. 〈inserm-00615490〉

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