The atspo11-1 mutation rescues atxrcc3 meiotic chromosome fragmentation.

Abstract : Homologous recombination events occurring during meiotic prophase I ensure the proper segregation of homologous chromosomes at the first meiotic division. These events are initiated by programmed double-strand breaks produced by the Spo11 protein and repair of such breaks by homologous recombination requires a strand exchange activity provided by the Rad51 protein. We have recently reported that the absence of AtXrcc3, an Arabidopsis Rad51 paralogue, leads to extensive chromosome fragmentation during meiosis, first visible in diplotene of meiotic prophase I. The present study clearly shows that this fragmentation results from un- or mis-repaired AtSpo11-1 induced double-strand breaks and is thus due to a specific defect in the meiotic recombination process.
Type de document :
Article dans une revue
Plant Molecular Biology, Springer Verlag (Germany), 2004, 56 (2), pp.217-24. 〈10.1007/s11103-004-2812-4〉
Liste complète des métadonnées

http://www.hal.inserm.fr/inserm-00595809
Contributeur : Charles White <>
Soumis le : mercredi 25 mai 2011 - 15:58:40
Dernière modification le : jeudi 11 janvier 2018 - 06:23:14

Lien texte intégral

Identifiants

Collections

Citation

Jean-Yves Bleuyard, Maria Gallego, Charles White. The atspo11-1 mutation rescues atxrcc3 meiotic chromosome fragmentation.. Plant Molecular Biology, Springer Verlag (Germany), 2004, 56 (2), pp.217-24. 〈10.1007/s11103-004-2812-4〉. 〈inserm-00595809〉

Partager

Métriques

Consultations de la notice

74