Endothelial estrogen receptor {alpha} plays an essential role in the coronary and myocardial protective effects of estradiol in ischemia/reperfusion.

Abstract : Endothelial ERα plays a crucial role in the E2-induced prevention of endothelial dysfunction after I/R. To our knowledge, we demonstrate for the first time, by using unique genetically modified mice, that targeting endothelial protection per se can confer cardiomyocyte protection in I/R.
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Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2010, 30 (12), pp.2562-7. 〈10.1161/ATVBAHA.110.213637〉
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Contributeur : Marie Francoise Simon <>
Soumis le : vendredi 31 décembre 2010 - 15:46:19
Dernière modification le : mardi 5 juin 2018 - 10:14:22

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Julie Favre, Ji Gao, Jean-Paul Henry, Isabelle Remy-Jouet, Isabelle Fourquaux, et al.. Endothelial estrogen receptor {alpha} plays an essential role in the coronary and myocardial protective effects of estradiol in ischemia/reperfusion.. Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2010, 30 (12), pp.2562-7. 〈10.1161/ATVBAHA.110.213637〉. 〈inserm-00550876〉

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