PMID: identifier of
Pubmed reference: |
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 (21055768) |
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| title: |
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Distinguishing the relevant features of frequent suicide attempters. |
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| author(s): |
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Jorge Lopez-Castroman ( ) 1, Maria De Las Mercedes Perez-Rodriguez2, Isabelle Jaussent3, 4, Analucia Alegria5, 6, Antonio Artes-Rodriguez7, Peter Freed5, Sébastien Guillaume3, 4, Fabrice Jollant3, 4, Jose Miguel Leiva-Murillo7, Alain Malafosse3, 4, Maria Oquendo5, Mario De Prado-Cumplido7, Jeronimo Saiz-Ruiz6, 8, 9, Enrique Baca-Garcia1, 5, 6, Philippe Courtet3, 4, For the European Research Consortium for Suicide (EURECA) collaboration(s) |
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| laboratory: |
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| short title : |
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Features of frequent suicide attempters |
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| abstract: |
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BACKGROUND: In spite of the high prevalence of suicide behaviours and the magnitude of the resultant burden, little is known about why individuals reattempt. We aim to investigate the relationships between clinical risk factors and the repetition of suicidal attempts. METHODS: 1349 suicide attempters were consecutively recruited in the Emergency Room (ER) of two academic hospitals in France and Spain. Patients were extensively assessed and demographic and clinical data obtained. Data mining was used to determine the minimal number of variables that blinded the rest in relation to the number of suicide attempts. Using this set, a probabilistic graph ranking relationships with the target variable was constructed. RESULTS: The most common diagnoses among suicide attempters were affective disorders, followed by anxiety disorders. Risk of frequent suicide attempt was highest among middle-aged subjects, and diminished progressively with advancing age of onset at first attempt. Anxiety disorders significantly increased the risk of presenting frequent suicide attempts. Pathway analysis also indicated that frequent suicide attempts were linked to greater odds for alcohol and substance abuse disorders and more intensive treatment. CONCLUSIONS: Novel statistical methods found several clinical features that were associated with a history of frequent suicide attempts. The identified pathways may promote new hypothesis-driven studies of suicide attempts and preventive strategies. |
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| subject: |
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| fulltext language: |
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English |
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| ISSN: |
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1879-1379 |
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| publication format: |
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Article in peer-reviewed journal |
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| DOI: |
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10.1016/j.jpsychires.2010.09.017 |
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| journal: |
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| Journal of Psychiatric Research (J Psychiatr Res) |
| Publisher |
Elsevier |
| ISSN |
0022-3956 |
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| Audience: |
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international |
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| publication date: |
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2011-05 |
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| submission date: |
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2010-11-04 |
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| volume: |
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45 |
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| issue: |
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5 |
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| page, identifiant, ...: |
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619-25 |
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| MeSH Descriptor(s): |
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Adult – Female – France – Humans – Interview – Psychological – Male – Middle Aged – Prevalence – Probability – Psychiatric Status Rating Scales – ROC Curve – Risk Factors – Spain – Suicide – Attempted |
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