Which IMRT? From "step and shoot" to VMAT: physicist point of view

Abstract : Intensity-modulated radiation therapy (IMRT) is essential to have a dose distribution matching with the planning target volume (PTV) in case of concave-shape target. Today IMRT delivery techniques with linear accelerator can be divided into two classes: techniques with fixed gantry, called "step and shoot" (S&S) and "sliding window" (SW), and rotational techniques, called intensity modulated arc therapy (IMAT) and volumetric modulated arc therapy (VMAT). We discuss about constraints for IMRT implementation from dosimetric planning to treatment delivery. We compare S&S and VMAT performances concerning dose distribution quality, efficiency and delivery time. We describe quality controls that must be implemented and the methods for analysis and follow-up performances. VMAT tends to yield similar dose distribution to MRT with fixed gantry. VMAT also decreases monitor units as well as treatment delivery time to less than 5 minutes. However, VMAT is an IMRT technique more difficult to master than S&S technique because there are more variable parameters.
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Caroline Lafond, F. Jouyaux, J. Bellec, O. Henry, M. Perdrieux, et al.. Which IMRT? From "step and shoot" to VMAT: physicist point of view. Cancer Radiothérapie, Elsevier Masson, 2010, 14 (6-7), pp.539-49. 〈10.1016/j.canrad.2010.06.012〉. 〈inserm-00526904〉

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