M. J. Berridge, P. Lipp, and M. D. Bootman, SIGNAL TRANSDUCTION:The Calcium Entry Pas de Deux, Science, vol.287, issue.5458, pp.1604-1605, 2000.
DOI : 10.1126/science.287.5458.1604

L. K. Nutt, A. Pataer, J. Pahler, B. Fang, J. Roth et al., Bax and Bak Promote Apoptosis by Modulating Endoplasmic Reticular and Mitochondrial Ca2+ Stores, Journal of Biological Chemistry, vol.277, issue.11, pp.9219-9225, 2002.
DOI : 10.1074/jbc.M106817200

B. Tombal, S. R. Denmeade, J. M. Gillis, and J. T. Isaacs, A supramicromolar elevation of intracellular free calcium ([Ca2+]i) is consistently required to induce the execution phase of apoptosis, Cell Death and Differentiation, vol.9, issue.5, pp.561-573, 2002.
DOI : 10.1038/sj.cdd.4400999

R. Rizzuto, P. Pinton, D. Ferrari, M. Chami, G. Szabadkai et al., Calcium and apoptosis: facts and hypotheses, Oncogene, vol.22, issue.53, pp.8619-8627, 2003.
DOI : 10.1038/sj.onc.1207105

F. , D. Sano, E. Ferraro, R. Tufi, T. Achsel et al., Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism, J Biol Chem, vol.281, pp.2693-2700, 2006.

A. Masud, A. Mohapatra, S. A. Lakhani, A. Ferrandino, R. Hakem et al., Endoplasmic Reticulum Stress-induced Death of Mouse Embryonic Fibroblasts Requires the Intrinsic Pathway of Apoptosis, Journal of Biological Chemistry, vol.282, issue.19, pp.14132-14139, 2007.
DOI : 10.1074/jbc.M700077200

R. V. Rao, K. S. Poksay, S. Castro-obregon, B. Schilling, R. H. Row et al., Molecular Components of a Cell Death Pathway Activated by Endoplasmic Reticulum Stress, Journal of Biological Chemistry, vol.279, issue.1, pp.177-187, 2004.
DOI : 10.1074/jbc.M304490200

H. Suzuki, M. Kawasaki, T. Inuzuka, M. Okumura, T. Kakiuchi et al., Structural Basis for Ca2+-Dependent Formation of ALG-2/Alix Peptide Complex: Ca2+/EF3-Driven Arginine Switch Mechanism, Structure, vol.16, issue.10, pp.1562-1573, 2008.
DOI : 10.1016/j.str.2008.07.012

K. Katoh, H. Shibata, H. Suzuki, A. Nara, K. Ishidoh et al., The ALG-2-interacting Protein Alix Associates with CHMP4b, a Human Homologue of Yeast Snf7 That Is Involved in Multivesicular Body Sorting, Journal of Biological Chemistry, vol.278, issue.40, pp.39104-39113, 2003.
DOI : 10.1074/jbc.M301604200

M. Missotten, A. Nichols, K. Rieger, and R. Sadoul, Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein, Cell Death and Differentiation, vol.6, issue.2, pp.124-129, 1999.
DOI : 10.1038/sj.cdd.4400456

P. Vito, L. Pellegrini, C. Guiet, and L. D. Adamio, Cloning of AIP1, a Novel Protein That Associates with the Apoptosis-linked Gene ALG-2 in a Ca2+-dependent Reaction, Journal of Biological Chemistry, vol.274, issue.3, pp.1533-1540, 1999.
DOI : 10.1074/jbc.274.3.1533

R. Sadoul, Do Alix and ALG-2 really control endosomes for better or for worse?, Biology of the Cell, vol.14, issue.1, pp.69-77, 2006.
DOI : 10.1042/BC20050007
URL : https://hal.archives-ouvertes.fr/inserm-00381819

G. Odorizzi, The multiple personalities of Alix, Journal of Cell Science, vol.119, issue.15, pp.3025-3032, 2006.
DOI : 10.1242/jcs.03072

F. J. Hemming, S. Fraboulet, B. Blot, and R. Sadoul, Early increase of apoptosis-linked gene-2 interacting protein X in areas of kainate-induced neurodegeneration, Neuroscience, vol.123, issue.4, pp.887-895, 2004.
DOI : 10.1016/j.neuroscience.2003.10.036

Y. Trioulier, S. Torch, B. Blot, N. Cristina, C. Chatellard-causse et al., Alix, a Protein Regulating Endosomal Trafficking, Is Involved in Neuronal Death, Journal of Biological Chemistry, vol.279, issue.3, pp.2046-2052, 2004.
DOI : 10.1074/jbc.M309243200
URL : https://hal.archives-ouvertes.fr/inserm-00381892

A. L. Mahul-mellier, F. J. Hemming, B. Blot, S. Fraboulet, and R. Sadoul, Alix, Making a Link between Apoptosis-Linked Gene-2, the Endosomal Sorting Complexes Required for Transport, and Neuronal Death In Vivo, Journal of Neuroscience, vol.26, issue.2, pp.542-549, 2006.
DOI : 10.1523/JNEUROSCI.3069-05.2006
URL : https://hal.archives-ouvertes.fr/inserm-00381816

A. L. Mahul-mellier, F. Strappazzon, A. Petiot, C. Chatellard-causse, S. Torch et al., Alix and ALG-2 Are Involved in Tumor Necrosis Factor Receptor 1-induced Cell Death, Journal of Biological Chemistry, vol.283, issue.50, pp.34954-34965, 2008.
DOI : 10.1074/jbc.M803140200
URL : https://hal.archives-ouvertes.fr/inserm-00381799

A. L. Mahul-mellier, F. Strappazzon, C. Chatellard-causse, B. Blot, D. Beal et al., Alix and ALG-2 make a link between endosomes and neuronal death, Biochemical Society Transactions, vol.37, issue.1, pp.200-203, 2009.
DOI : 10.1042/BST0370200
URL : https://hal.archives-ouvertes.fr/inserm-00381793

C. Chatellard-causse, B. Blot, N. Cristina, S. Torch, M. Missotten et al., Alix (ALG-2-interacting Protein X), a Protein Involved in Apoptosis, Binds to Endophilins and Induces Cytoplasmic Vacuolization, Journal of Biological Chemistry, vol.277, issue.32, pp.29108-29115, 2002.
DOI : 10.1074/jbc.M204019200

T. Tuomikoski, M. A. Felix, M. Doree, and J. Gruenberg, Inhibition of endocytic vesicle fusion in vitro by the cell-cycle control protein kinase cdc2, Nature, vol.342, issue.6252, pp.942-945, 1989.
DOI : 10.1038/342942a0

A. Jimbo, E. Fujita, Y. Kouroku, J. Ohnishi, N. Inohara et al., ER stress induces caspase-8 activation, stimulating cytochrome c release and caspase-9 activation, Experimental Cell Research, vol.283, issue.2, pp.156-166, 2003.
DOI : 10.1016/S0014-4827(02)00033-2

E. A. Obeng and L. H. Boise, Caspase-12 and Caspase-4 Are Not Required for Caspase-dependent Endoplasmic Reticulum Stress-induced Apoptosis, Journal of Biological Chemistry, vol.280, issue.33, pp.29578-29587, 2005.
DOI : 10.1074/jbc.M502685200

D. Blum, F. J. Hemming, M. C. Galas, S. Torch, L. Cuvelier et al., Increased Alix (apoptosis-linked gene-2 interacting protein X) immunoreactivity in the degenerating striatum of rats chronically treated by 3-nitropropionic acid, Neuroscience Letters, vol.368, issue.3, pp.368-309, 2004.
DOI : 10.1016/j.neulet.2004.07.046
URL : https://hal.archives-ouvertes.fr/inserm-00381837

Y. Kosuge, T. Sakikubo, K. Ishige, and Y. Ito, Comparative study of endoplasmic reticulum stress-induced neuronal death in rat cultured hippocampal and cerebellar granule neurons, Neurochemistry International, vol.49, issue.3, pp.285-293, 2006.
DOI : 10.1016/j.neuint.2006.01.021

H. Shiraishi, H. Okamoto, A. Yoshimura, and H. Yoshida, ER stress-induced apoptosis and caspase-12 activation occurs downstream of mitochondrial apoptosis involving Apaf-1, Journal of Cell Science, vol.119, issue.19, pp.3958-3966, 2006.
DOI : 10.1242/jcs.03160

I. Draeby, Y. L. Woods, J. M. La-cour, J. Mollerup, J. C. Bourdon et al., The calcium binding protein ALG-2 binds and stabilizes Scotin, a p53-inducible gene product localized at the endoplasmic reticulum membrane, Archives of Biochemistry and Biophysics, vol.467, issue.1, pp.87-94, 2007.
DOI : 10.1016/j.abb.2007.07.028
URL : https://hal.archives-ouvertes.fr/inserm-00409606

J. M. La-cour, J. Mollerup, and M. W. Berchtold, ALG-2 oscillates in subcellular localization, unitemporally with calcium oscillations, Biochemical and Biophysical Research Communications, vol.353, issue.4, pp.1063-1067, 2007.
DOI : 10.1016/j.bbrc.2006.12.143

H. Shibata, H. Suzuki, H. Yoshida, and M. Maki, ALG-2 directly binds Sec31A and localizes at endoplasmic reticulum exit sites in a Ca2+-dependent manner, Biochemical and Biophysical Research Communications, vol.353, issue.3, pp.756-763, 2007.
DOI : 10.1016/j.bbrc.2006.12.101

A. Yamasaki, K. Tani, A. Yamamoto, N. Kitamura, and M. Komada, The Ca2+-binding Protein ALG-2 Is Recruited to Endoplasmic Reticulum Exit Sites by Sec31A and Stabilizes the Localization of Sec31A, Molecular Biology of the Cell, vol.17, issue.11, pp.4876-4887, 2006.
DOI : 10.1091/mbc.E06-05-0444