PMID: identifier of
Pubmed reference: |
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 (20479514) |
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| title: |
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Intra-operative ultrasound hand-held strain imaging for the visualization of ablations produced in the liver with a toroidal HIFU transducer: first in vivo results. |
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| author(s): |
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Jérémy Chenot ( ) 1, David Melodelima1, William Apoutou N'Djin1, Rémi Souchon1, Michel Rivoire1, Jean-Yves Chapelon1 |
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| laboratory: |
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| abstract: |
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The use of hand-held ultrasound strain imaging for the intra-operative real-time visualization of HIFU (high-intensity focused ultrasound) ablations produced in the liver by a toroidal transducer was investigated. A linear 12 MHz ultrasound imaging probe was used to obtain radiofrequency signals. Using a fast cross-correlation algorithm, strain images were calculated and displayed at 60 frames s(-1), allowing the use of hand-held strain imaging intra-operatively. Fourteen HIFU lesions were produced in four pigs. Intra-operative strain imaging of HIFU ablations in the liver was feasible owing to the high frame rate. The correlation between dimensions measured on gross pathology and dimensions measured on B-mode images and on strain images were R = 0.72 and R = 0.94 respectively. The contrast between ablated and non-ablated tissue was significantly higher (p < 0.05) in the strain images (22 dB) than in the B-mode images (9 dB). Strain images allowed equivalent or improved definition of ablated regions when compared with B-mode images. Real-time intra-operative hand-held strain imaging seems to be a promising complement to conventional B-mode imaging for the guidance of HIFU ablations produced in the liver during an open procedure. These results support that hand-held strain imaging outperforms conventional B-mode ultrasound and could potentially be used for the assessment of thermal therapies. |
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| subject: |
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| fulltext language: |
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English |
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| ISSN: |
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0031-9155 |
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| publication format: |
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Peer-reviewed article |
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| DOI: |
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10.1088/0031-9155/55/11/010 |
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| journal: |
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| Physics in Medicine and Biology (Phys Med Biol) |
| Publisher |
Institute of Physics (IOP) |
| ISSN |
0031-9155 (eISSN : 1361-6560) |
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| Audience: |
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international |
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| publication date: |
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2010-06-07 |
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| submission date: |
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2010-05-17 |
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| volume: |
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55 |
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| issue: |
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11 |
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| page, identifiant, ...: |
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3131-44 |
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