Changes in thymic function with age and during the treatment of HIV infection, Nature, vol.396, pp.690-695, 1998. ,
Immunosenescence of ageing, The Journal of Pathology, vol.33, issue.2, pp.144-156, 2007. ,
DOI : 10.1002/path.2104
The incidence of congenital heart disease, Journal of the American College of Cardiology, vol.39, issue.12, pp.1890-1900, 2002. ,
DOI : 10.1016/S0735-1097(02)01886-7
Immunological decay in thymectomized infants, Helv. Paediatr. Acta, vol.30, pp.425-433, 1976. ,
Imbalances in T cell subpopulations associated with immunodeficiency and autoimmune syndromes, European Journal of Immunology, vol.24, issue.10, pp.696-700, 1977. ,
DOI : 10.1002/eji.1830071009
Neonatal thymectomy: Does it affect immune function?, The Journal of Thoracic and Cardiovascular Surgery, vol.115, issue.5, pp.1041-1046, 1998. ,
DOI : 10.1016/S0022-5223(98)70403-9
The influence of partial or total thymectomy during open heart surgery in infants on the immune function later in life, Clinical and Experimental Immunology, vol.778, issue.2, pp.349-355, 2004. ,
DOI : 10.1016/S0955-0674(00)00132-0
Levels of Recent Thymic Emigrant Cells Decrease in Children Undergoing Partial Thymectomy during Cardiac Surgery, Clinical and Vaccine Immunology, vol.12, issue.5, pp.563-565, 2005. ,
DOI : 10.1128/CDLI.12.5.563-565.2005
Evidence for extrathymic T cell maturation after thymectomy in infancy, Clinical and Experimental Immunology, vol.70, issue.3, pp.407-412, 2006. ,
DOI : 10.1016/S0955-0674(00)00132-0
Effacing of the T Cell Compartment by Cardiac Transplantation in Infancy, The Journal of Immunology, vol.176, issue.3, 2006. ,
DOI : 10.4049/jimmunol.176.3.1962
Thymectomy in early childhood: Significant alterations of the CD4+CD45RA+CD62L+ T cell compartment in later life, Clinical Immunology, vol.130, issue.2, pp.123-132, 2009. ,
DOI : 10.1016/j.clim.2008.08.023
Two Subsets of Naive T Helper Cells with Distinct T Cell Receptor Excision Circle Content in Human Adult Peripheral Blood, The Journal of Experimental Medicine, vol.163, issue.6, pp.789-794, 2002. ,
DOI : 10.1073/pnas.97.16.9203
Correlation between recent thymic emigrants and CD31+ (PECAM-1) CD4+ T cells in normal individuals during aging and in lymphopenic children, European Journal of Immunology, vol.25, issue.11, pp.3270-3280, 2007. ,
DOI : 10.1002/eji.200636976
Phenotype and function of human T lymphocyte subsets: Consensus and issues, Cytometry Part A, vol.13, issue.11, pp.975-983, 2008. ,
DOI : 10.1002/cyto.a.20643
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells, Blood, vol.101, issue.7, pp.2711-2720, 2003. ,
DOI : 10.1182/blood-2002-07-2103
Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection, PLoS Biology, vol.195, issue.2, p.20, 2004. ,
DOI : 10.1371/journal.pbio.0020020.t001
CD8+ T cell efficacy in vaccination and disease, Nature Medicine, vol.205, issue.6, pp.623-628, 2008. ,
DOI : 10.1038/nm.f.1774
T-cell quality in memory and protection: implications for vaccine design, Nature Reviews Immunology, vol.27, issue.4, pp.247-258, 2008. ,
DOI : 10.1038/nri2274
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections, Nature Medicine, vol.8, issue.4, pp.379-385, 2002. ,
DOI : 10.1038/nm0402-379
Human CD8+ T-cell differentiation in response to viruses, Nature Reviews Immunology, vol.3, issue.12, pp.931-939, 2003. ,
DOI : 10.1038/nri1254
Linear Differentiation of Cytotoxic Effectors into Memory T Lymphocytes, Science, vol.283, issue.5408, pp.1745-1748, 1999. ,
DOI : 10.1126/science.283.5408.1745
CD4(+) T cell effectors can become memory cells with high efficiency and without further division, Nature Immunology, vol.190, issue.8, pp.705-710, 2001. ,
DOI : 10.1038/90643
Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory, Nature Medicine, vol.7, issue.8, pp.913-919, 2001. ,
DOI : 10.1038/90950
Cutting Edge: CD4 and CD8 T Cells Are Intrinsically Different in Their Proliferative Responses, The Journal of Immunology, vol.168, issue.4, pp.1528-1532, 2002. ,
DOI : 10.4049/jimmunol.168.4.1528
Antigen challenge leads to in vivo activation and elimination of highly polarized TH1 memory T cells, Proceedings of the National Academy of Sciences, vol.99, issue.9, pp.6187-6191, 2002. ,
DOI : 10.1073/pnas.092129899
Programmed contraction of CD8+ T cells after infection, Nature Immunology, vol.3, pp.619-626, 2002. ,
DOI : 10.1038/ni804
Distinct lineages of TH1 cells have differential capacities for memory cell generation in vivo, Nature Immunology, vol.3, issue.9, pp.852-858, 2002. ,
DOI : 10.1038/ni832
The Poststimulation Program of CD4 Versus CD8 T Cells (Death Versus Activation-Induced Nonresponsiveness), The Journal of Immunology, vol.169, issue.4, 2002. ,
DOI : 10.4049/jimmunol.169.4.1822
Differential Survival of Naive CD4 and CD8 T Cells, The Journal of Immunology, vol.165, issue.7, pp.3689-3694, 2000. ,
DOI : 10.4049/jimmunol.165.7.3689
Frequencies of Circulating Cytolytic, CD45RA+CD27-, CD8+ T Lymphocytes Depend on Infection with CMV, The Journal of Immunology, vol.170, issue.8, pp.4342-4348, 2003. ,
DOI : 10.4049/jimmunol.170.8.4342
T cells dominate the memory compartments of exposed subjects, The Journal of Experimental Medicine, vol.70, issue.5, pp.673-685, 2005. ,
DOI : 10.1182/blood-2003-06-1937
Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation, Immunological Reviews, vol.174, issue.1, pp.256-271, 2006. ,
DOI : 10.1084/jem.20051100
Immune Parameters in a Longitudinal Study of a Very Old Population of Swedish People: A Comparison Between Survivors and Nonsurvivors, The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, vol.50, issue.6, pp.378-382, 1995. ,
DOI : 10.1093/gerona/50A.6.B378
Changes in CD8 and CD4 lymphocyte subsets, T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO-immune study, Mechanisms of Ageing and Development, vol.102, issue.2-3, pp.187-198, 1998. ,
DOI : 10.1016/S0047-6374(97)00151-6
Diminished response to tick-borne encephalitis vaccination in thymectomized children, Vaccine, vol.26, issue.5, pp.595-600, 2008. ,
DOI : 10.1016/j.vaccine.2007.11.074
The Influence of Age on T Cell Generation and TCR Diversity, The Journal of Immunology, vol.174, issue.11, pp.7446-7452, 2005. ,
DOI : 10.4049/jimmunol.174.11.7446
Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection, The Journal of Experimental Medicine, vol.105, issue.10, pp.2263-2269, 2006. ,
DOI : 10.4049/jimmunol.172.8.4875
Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus, The Journal of Experimental Medicine, vol.69, issue.3, pp.711-723, 2008. ,
DOI : 10.1073/pnas.90.9.4319
The many important facets of T-cell repertoire diversity, Nature Reviews Immunology, vol.14, issue.2, pp.123-132, 2004. ,
DOI : 10.1126/science.286.5446.1913
Peripheral T cell expansion in lymphopenic mice results in a restricted T cell repertoire, European Journal of Immunology, vol.178, issue.12, pp.3380-3386, 2000. ,
DOI : 10.1002/1521-4141(2000012)30:12<3380::AID-IMMU3380>3.0.CO;2-P
Role of Thymic Output in Regulating CD8 T-Cell Homeostasis during Acute and Chronic Viral Infection, Journal of Virology, vol.79, issue.15, pp.9419-9429, 2005. ,
DOI : 10.1128/JVI.79.15.9419-9429.2005
Ablation of thymic export causes accelerated decay of naive CD4 T cells in the periphery because of activation by environmental antigen, Proceedings of the National Academy of Sciences, vol.105, issue.25, pp.8691-8696, 2008. ,
DOI : 10.1073/pnas.0803732105
Memory Inflation: Continuous Accumulation of Antiviral CD8+ T Cells Over Time, The Journal of Immunology, vol.170, issue.4, pp.2022-2029, 2003. ,
DOI : 10.4049/jimmunol.170.4.2022
Enrichment of Immediate-Early 1 (m123/pp89) Peptide-Specific CD8 T Cells in a Pulmonary CD62Llo Memory-Effector Cell Pool during Latent Murine Cytomegalovirus Infection of the Lungs, Journal of Virology, vol.74, issue.24, pp.11495-11503, 2000. ,
DOI : 10.1128/JVI.74.24.11495-11503.2000
Memory Inflation during Chronic Viral Infection Is Maintained by Continuous Production of Short-Lived, Functional T Cells, Immunity, vol.29, issue.4, pp.650-659, 2008. ,
DOI : 10.1016/j.immuni.2008.07.017
Human Immunosenescence: Does It Have an Infectious Component?, Annals of the New York Academy of Sciences, vol.141, issue.1, pp.56-65, 2006. ,
DOI : 10.1182/blood-2002-02-0657
Human cytomegalovirus infection and T cell immunosenescence: A mini review, Mechanisms of Ageing and Development, vol.127, issue.6, pp.538-543, 2006. ,
DOI : 10.1016/j.mad.2006.01.011
Cytomegalovirus (CMV) infection, CD4+ lymphocyte counts and the development of AIDS in HIV-1-infected haemophiliac patients, Clinical & Experimental Immunology, vol.143, issue.SI, pp.6-9, 1992. ,
DOI : 10.1111/j.1365-2249.1992.tb03030.x
Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo, Nature Immunology, vol.1, issue.5, pp.426-432, 2000. ,
DOI : 10.1038/80868
IL-7 is critical for homeostatic proliferation and survival of naive T cells, Proceedings of the National Academy of Sciences, vol.98, issue.15, pp.8732-8737, 2001. ,
DOI : 10.1073/pnas.161126098
Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets, The Journal of Experimental Medicine, vol.153, issue.7, pp.1701-1714, 2008. ,
DOI : 10.1016/0198-8859(96)00076-6
Enhanced T cell recovery in HIV-1???infected adults through IL-7 treatment, Journal of Clinical Investigation, 2009. ,
DOI : 10.1172/JCI38052
URL : https://hal.archives-ouvertes.fr/inserm-00484803
IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection, Blood, vol.113, issue.25, pp.6304-6314, 2009. ,
DOI : 10.1182/blood-2008-10-186601
Phenotypic Analysis of Antigen-Specific T Lymphocytes, Science, vol.274, issue.5284, pp.182194-96, 1996. ,
DOI : 10.1126/science.274.5284.94
The assessment of antigen-specific CD8+ T cells through the combination of MHC class I tetramer and intracellular staining, Journal of Immunological Methods, vol.268, issue.1, pp.9-19, 2002. ,
DOI : 10.1016/S0022-1759(02)00195-3
Retrovirus-Mediated Gene Transfer in Human Primary T Lymphocytes Induces an Activation- and Transduction/Selection-Dependent TCR-B Variable Chain Repertoire Skewing of Gene-Modified Cells, Stem Cells and Development, vol.13, issue.1, pp.71-81, 2004. ,
DOI : 10.1089/154732804773099272
Human T-cell receptor variable gene segment families, Immunogenetics, vol.42, issue.6, pp.455-500, 1995. ,
DOI : 10.1007/BF00172176