E. Kuhn and M. Lavielle, Maximum likelihood estimation in nonlinear mixed effects models . Computational Statistics and Data Analysis, MONOLIX 2.4 User Guide, pp.1020-1038, 2005.

P. Girard and F. Mentre, A comparison of estimation methods in nonlinear mixed effects models using a blind analysis, pp.14-2005

K. Brendel, E. Comets, C. Laffont, C. Laveille, and F. Mentre, Metrics for External Model Evaluation with an Application to the Population Pharmacokinetics of Gliclazide, Pharmaceutical Research, vol.91, issue.9
DOI : 10.1007/s11095-006-9067-5

URL : https://hal.archives-ouvertes.fr/inserm-00189557

M. Karlsson and N. Holford, A Tutorial on Visual Predictive Checks 17 -2008 ; Abstr 1434http://www.page-meeting.org/?abstract=1434 Marseille 17, Savic RM , KMO . Importance of Shrinkage in Empirical Bayes Estimates for Diagnostics and Estimation: Problems and Solutions, pp.16-2007

U. Wahlby, E. Jonsson, and M. Karlsson, Assessment of actual significance levels for covariate effects in NONMEM, Journal of Pharmacokinetics and Pharmacodynamics, vol.28, issue.3, pp.231-252, 2001.
DOI : 10.1023/A:1011527125570

M. Lavielle and F. Mentre, Estimation of Population Pharmacokinetic Parameters of Saquinavir in HIV Patients with the MONOLIX Software, Journal of Pharmacokinetics and Pharmacodynamics, vol.32, issue.2, pp.229-249, 2007.
DOI : 10.1007/s10928-006-9043-z

URL : https://hal.archives-ouvertes.fr/inserm-00156907