E. Lander and N. Schork, Genetic dissection of complex traits, Science, vol.265, issue.5181, pp.2037-2048, 1994.
DOI : 10.1126/science.8091226

N. Andrieu and A. Goldstein, Epidemiologic and Genetic Approaches in the Study of Gene-Environment Interaction: an Overview of Available Methods, Epidemiologic Reviews, vol.20, issue.2, pp.137-147, 1998.
DOI : 10.1093/oxfordjournals.epirev.a017976

R. Ottman, Gene???Environment Interaction: Definitions and Study Design, Preventive Medicine, vol.25, issue.6, pp.764-770, 1996.
DOI : 10.1006/pmed.1996.0117

Q. Yang and M. Khoury, Evolving Methods in Genetic Epidemiology. III. Gene-Environment Interaction in Epidemiologic Research, Epidemiologic Reviews, vol.19, issue.1, pp.33-43, 1997.
DOI : 10.1093/oxfordjournals.epirev.a017944

P. Kraft, Y. Yen, D. Stram, J. Morrison, and W. Gauderman, Exploiting Gene-Environment Interaction to Detect Genetic Associations, Human Heredity, vol.63, issue.2, pp.111-119, 2007.
DOI : 10.1159/000099183

H. Selinger-leneman, E. Genin, J. Norris, and M. Khlat, Does accounting for gene-environment (G??E) interaction increase the power to detect the effect of a gene in a multifactorial disease?, Genetic Epidemiology, vol.66, issue.3, pp.200-207, 2003.
DOI : 10.1002/gepi.10221

S. Purcell, Variance Components Models for Gene???Environment Interaction in Twin Analysis, Twin Research, vol.5, issue.6, pp.554-571, 2002.
DOI : 10.1375/136905202762342026

I. Stücker, C. Bonaïti-pellié, D. Hémon, A. Hirsch, M. Goldberg et al., Epidemiology of lung cancer: interaction between genetic susceptibility and environmental risk factors Prevention of respiratory diseases, pp.149-165, 1993.

N. Risch, Linkage strategies for genetically complex traits. I. Multilocus models

M. Khoury, T. Beaty, and K. Liang, CAN FAMILIAL AGGREGATION OF DISEASE BE EXPLAINED BY FAMILIAL AGGREGATION OF ENVIRONMENTAL RISK FACTORS?, American Journal of Epidemiology, vol.127, issue.3, pp.674-683, 1988.
DOI : 10.1093/oxfordjournals.aje.a114842

C. Li and L. Sacks, The Derivation of Joint Distribution and Correlation between Relatives by the Use of Stochastic Matrices, Biometrics, vol.10, issue.3, pp.347-360, 1954.
DOI : 10.2307/3001590

T. Nelson, T. Fingerlin, L. Moss, M. Barmada, R. Ferrell et al., Association of the peroxisome proliferator???activated receptor ?? gene with type 2 diabetes mellitus varies by physical activity among non-Hispanic whites from Colorado, Metabolism, vol.56, issue.3, pp.388-393, 2007.
DOI : 10.1016/j.metabol.2006.10.022

A. Kriska, W. Knowler, and R. Laporte, Development of Questionnaire to Examine Relationship of Physical Activity and Diabetes in Pima Indians, Diabetes Care, vol.13, issue.4, pp.401-411, 1990.
DOI : 10.2337/diacare.13.4.401

J. Lynch, S. Helmrich, and T. Lakka, Moderately Intense Physical Activities and High Levels of Cardiorespiratory Fitness Reduce the Risk of Non-Insulin-Dependent Diabetes Mellitus in Middle-aged Men, National diabetes surveillance system, US Department of Health and Human Services. Diabetes Data for Colorado, pp.1307-1314, 1984.
DOI : 10.1001/archinte.1996.00440110073010

M. Mahon and B. , Epidemiologic approaches to family resemblance Genetic Epidemiology, pp.3-11, 1978.

D. Umbach and C. Weinberg, The Use of Case-Parent Triads to Study Joint Effects of Genotype and Exposure, The American Journal of Human Genetics, vol.66, issue.1, pp.251-261, 2000.
DOI : 10.1086/302707

N. Andrieu, A. Goldstein, D. Thomas, and B. Langholz, Counter-Matching in Studies of Gene-Environment Interaction: Efficiency and Feasibility, American Journal of Epidemiology, vol.153, issue.3, pp.265-274, 2001.
DOI : 10.1093/aje/153.3.265

A. Goldstein, M. Dondon, and N. Andrieu, Unconditional analyses can increase efficiencyin assessing gene-environment interaction of the case-combined-control design, International Journal of Epidemiology, vol.35, issue.4, pp.1067-1073, 2006.
DOI : 10.1093/ije/dyl048

A. Kriska, A. Saremi, and R. Hanson, Physical Activity, Obesity, and the Incidence of Type 2 Diabetes in a High-Risk Population, American Journal of Epidemiology, vol.158, issue.7, pp.669-675, 2003.
DOI : 10.1093/aje/kwg191

C. Weijnen, S. Rich, J. Meigs, A. Krolewski, and J. Warram, Risk of diabetes in siblings of index cases with Type 2 diabetes: implications for genetic studies, Diabetic Medicine, vol.49, issue.1, pp.41-50, 2002.
DOI : 10.1086/302950