[Therapeutic agents targetting protein-protein interactions: myth or reality?]

Abstract : Protein-protein interactions have a key role in transduction pathways that regulate many cellular functions. Structural and functional properties of protein-protein interface are now better understood, therefore offering attractive opportunities for therapeutic intervention. Developping small molecules that modulate protein-protein interactions is challenging. Nethertheless, significant progress in this endeavour has been made on several fronts. Here, we use few illustrative examples to summarize recent work in this emerging field.
Type de document :
Article dans une revue
médecine/sciences, EDP Sciences, 2007, 23 (3), pp.273-8
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http://www.hal.inserm.fr/inserm-00413234
Contributeur : Claude Cochet <>
Soumis le : jeudi 3 septembre 2009 - 15:22:29
Dernière modification le : jeudi 3 septembre 2009 - 15:26:48

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  • HAL Id : inserm-00413234, version 1
  • PUBMED : 17349288

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Béatrice Laudet, Renaud Prudent, Odile Filhol, Claude Cochet. [Therapeutic agents targetting protein-protein interactions: myth or reality?]. médecine/sciences, EDP Sciences, 2007, 23 (3), pp.273-8. 〈inserm-00413234〉

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