X. Jouven, J. Empana, and P. Schwartz, Heart-Rate Profile during Exercise as a Predictor of Sudden Death, New England Journal of Medicine, vol.352, issue.19, pp.1951-1958, 2005.
DOI : 10.1056/NEJMoa043012

A. Diaz, M. Bourassa, and M. Guertin, Long-term prognostic of resting heart rate in patients with suspected or proven coronary heart disease, Eur Heart J, pp.967-974, 2005.

M. Metra, C. Torp-pedersen, and K. Swedberg, Influence of heart rate, blood pressure, and beta-blocker dose on outcome and the differences in outcome between carvedilol and metoprolol tartrate in patients with chronic heart failure: results from the COMET trial, European Heart Journal, vol.26, issue.21, pp.2259-2268, 2005.
DOI : 10.1093/eurheartj/ehi386

P. Lechat, J. Hulot, and S. Escolano, Heart rate and cardiac rhythm relationships with bisoprolol benefit in chronic heart failure in CIBIS II trial, ACC Current Journal Review, vol.10, issue.5, pp.1428-1433, 2001.
DOI : 10.1016/S1062-1458(01)00407-X

J. Kjekshus, Importance of heart rate in determining beta-blocker efficacy in acute and long-term acute myocardial infarction intervention trials, The American Journal of Cardiology, vol.57, issue.12, pp.43-49, 1986.
DOI : 10.1016/0002-9149(86)90888-X

M. Cucherat, Quantitative relationship between resting heart rate reduction and magnitude of clinical benefits in post-myocardial infarction: a meta-regression of randomized clinical trials, European Heart Journal, vol.28, issue.24, pp.3012-3017, 2007.
DOI : 10.1093/eurheartj/ehm489

S. Thackray, J. Ghosh, and G. Wright, The effect of altering heart rate on ventricular function in patients with heart failure treated with ??-blockers, American Heart Journal, vol.152, issue.4, pp.713-722, 2006.
DOI : 10.1016/j.ahj.2006.07.007

D. Logeart, J. Gueffet, and F. Rouzet, impacts cardiac function in patients with systolic heart failure and pacing: a pilot study, European Journal of Heart Failure, vol.153, issue.1, pp.53-57, 2009.
DOI : 10.1093/eurjhf/hfn016

X. Monnet, C. P. Ghaleh, and B. , Heart rate reduction during exercise-induced myocardial ischaemia and stunning, European Heart Journal, vol.25, issue.7, pp.579-586, 2004.
DOI : 10.1016/j.ehj.2003.10.010

L. Lucats, B. Ghaleh, and . Monnet, Conversion of post-systolic wall thickening into ejectional thickening by selective heart rate reduction during myocardial stunning, European Heart Journal, vol.28, issue.7, pp.872-879, 2007.
DOI : 10.1093/eurheartj/ehm030

J. Vilaine, C. Thollon, and N. Villeneuve, Procoralan, a new selective If current inhibitor, European Heart Journal Supplements, vol.5
DOI : 10.1016/S1520-765X(03)90005-8

A. Berdeaux, Preclinical Results with If Current Inhibition by Ivabradine, Drugs, vol.53, issue.Supplement 2, 2007.
DOI : 10.2165/00003495-200767002-00004

L. Simon, B. Ghaleh, and L. Puybasset, Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs, J Pharmacol Exp Ther, vol.275, pp.659-66, 1995.

P. Mulder, S. Barbier, and A. Chagraoui, Long-Term Heart Rate Reduction Induced by the Selective If Current Inhibitor Ivabradine Improves Left Ventricular Function and Intrinsic Myocardial Structure in Congestive Heart Failure, Circulation, vol.109, issue.13, pp.1674-1683, 2004.
DOI : 10.1161/01.CIR.0000118464.48959.1C

D. Ferrari, G. Mazzuero, A. Agnesina, and L. , Favourable effects of heart rate reduction with intravenous administration of ivabradine in patients with advanced heart failure???, European Journal of Heart Failure, vol.95, issue.6, pp.550-555, 2008.
DOI : 10.1016/j.ejheart.2008.04.005

V. Ciobotaru, M. Heimburger, and L. Louedec, Effect of Long-Term Heart Rate Reduction by If Current Inhibition on Pressure Overload-Induced Heart Failure in Rats, Journal of Pharmacology and Experimental Therapeutics, vol.324, issue.1, pp.43-49, 2008.
DOI : 10.1124/jpet.107.130237

P. Mulder and C. Thuillez, Heart Rate Slowing for Myocardial Dysfunction/Heart Failure, Ad Cardiol Basel: Karger, vol.43, pp.97-105, 2006.
DOI : 10.1159/000095431

P. Milliez, . Ms, and J. Nehme, Beneficial effects of delayed ivabradine treatment on cardiac anatomical and electrical remodelling in severe chronic heart failure, Am J Physiol Heart Circ Physiol, 2008.

E. Dedkov, W. Zheng, and L. Christensen, Preservation of coronary reserve by ivabradine-induced reduction in heart rate in infarcted rats is associated with decrease in perivascular collagen, AJP: Heart and Circulatory Physiology, vol.293, issue.1, pp.590-598, 2007.
DOI : 10.1152/ajpheart.00047.2007

A. Drouin, M. Gendron, E. Thorin, and M. Gillis, Chronic heart rate reduction by ivabradine prevents endothelial dysfunction in dyslipidaemic mice, British Journal of Pharmacology, vol.53, issue.4, pp.749-57, 2008.
DOI : 10.1038/bjp.2008.116

F. Custadis, M. Baumhäkel, and N. Schlimmer, Heart Rate Reduction by Ivabradine Reduces Oxidative Stress, Improves Endothelial Function, and Prevents Atherosclerosis in Apolipoprotein E-Deficient Mice, Circulation, vol.117, issue.18, pp.2377-2387, 2008.
DOI : 10.1161/CIRCULATIONAHA.107.746537

F. Vaillant, Q. Timour, and J. Descotes, Ivabradine Induces an Increase in Ventricular Fibrillation Threshold During Acute Myocardial Ischemia: An Experimental Study, Journal of Cardiovascular Pharmacology, vol.52, issue.6, pp.548-554, 2008.
DOI : 10.1097/FJC.0b013e3181913df4

G. Derumeaux, M. Ovize, and J. Loufoua, Assessment of Nonuniformity of Transmural Myocardial Velocities by Color-Coded Tissue Doppler Imaging : Characterization of Normal, Ischemic, and Stunned Myocardium, Circulation, vol.101, issue.12, pp.1390-1395, 2000.
DOI : 10.1161/01.CIR.101.12.1390

L. Lucats, B. Ghaleh, and X. Monnet, Conversion of post-systolic wall thickening into ejectional thickening by selective heart rate reduction during myocardial stunning, European Heart Journal, vol.28, issue.7, pp.872-879, 2007.
DOI : 10.1093/eurheartj/ehm030