K. L. Yang and M. J. Tobin, A Prospective Study of Indexes Predicting the Outcome of Trials of Weaning from Mechanical Ventilation, New England Journal of Medicine, vol.324, issue.21, pp.1445-1450, 1991.
DOI : 10.1056/NEJM199105233242101

J. J. Marini, Weaning from Mechanical Ventilation, New England Journal of Medicine, vol.324, issue.21, pp.1496-1498, 1991.
DOI : 10.1056/NEJM199105233242109

M. J. Tobin and K. Yang, Weaning from Mechanical Ventilation, In M. J, 1990.
DOI : 10.1016/B978-032304841-5.50046-7

F. Lemaire, Le sevrage de la ventilation mécanique, Ventilation Artificielle. Principes et applications, pp.275-286, 1994.

D. F. Sittig, N. L. Pace, R. M. Gardner, E. Beck, and A. H. Morris, Implementation of a Computerized Patient Advice System using the HELP clinical information system, Computers and Biomedical Research, vol.22, issue.5, pp.474-487, 1989.
DOI : 10.1016/0010-4809(89)90040-2

L. B. Beinlich, L. M. Sheiner, and . Fagan, The design and implementation of a ventilator management advisor, Artif. Intell. Med, vol.5, pp.67-82, 1993.

D. A. Tong, Weaning patients from mechanical ventilation. A knowledge-based system approach, Computer Methods and Programs in Biomedicine, vol.35, issue.4, pp.267-278, 1991.
DOI : 10.1016/0169-2607(91)90005-E

R. Rudowski, C. Frostell, and H. Gill, A knowledge-based support system for mechanical ventilation of the lungs. The KUSIVAR concept and prototype, Computer Methods and Programs in Biomedicine, vol.30, issue.1, 1989.
DOI : 10.1016/0169-2607(89)90123-5

N. R. Macintyre, Respiratory Function during Pressure Support Ventilation, Chest, vol.89, issue.5, pp.677-683, 1989.
DOI : 10.1378/chest.89.5.677

L. Brochard, F. Pluskwa, and F. Lemaire, Improved Efficacy of Spontaneous Breathing with Inspiratory Pressure Support, American Review of Respiratory Disease, vol.136, issue.2, pp.411-415, 1987.
DOI : 10.1164/ajrccm/136.2.411

L. Brochard, A. Harf, H. Lorino, and F. Lemaire, Inspiratory Pressure Support Prevents Diaphragmatic Fatigue during Weaning from Mechanical Ventilation, American Review of Respiratory Disease, vol.139, issue.2, pp.513-521, 1989.
DOI : 10.1164/ajrccm/139.2.513

F. Gasparetto and . Lemaire, Comparison of three methods of gradual withdrawal from ventilatory support during weaning from mechanical ventilation, Am. J. Respir. Crit. Care Med, vol.150, pp.896-903, 1994.

W. B. Van-de-graaff, K. Gordey, S. E. Dornseif, D. J. Dries, B. S. Kleinman et al., Pressure Support, Chest, vol.100, issue.4, pp.1082-1089, 1991.
DOI : 10.1378/chest.100.4.1082

P. Ershowsky and B. Krieger, Changes in breathing pattern during pressure support ventilation, Resp. Care, vol.32, pp.1011-1016, 1987.

H. Tokioka, S. Saito, and F. Kosaka, Effect of pressure support ventilation on breathing patterns and respiratory work, Intensive Care Medicine, vol.87, issue.8, pp.491-494, 1989.
DOI : 10.1007/BF00273558

. Motin, Oxygen cost of breathing and diaphragmatic pressure time-index, 1990.

J. F. Fiastro, M. P. Habib, and S. F. Quan, Pressure Support Compensation for Inspiratory Work due to Endotracheal Tubes and Demand Continuous Positive Airway Pressure, Chest, vol.93, issue.3, pp.499-505, 1988.
DOI : 10.1378/chest.93.3.499

L. Brochard, F. Rua, H. Lorino, F. Lemaire, and A. Harf, Inspiratory Pressure Support Compensates for the Additional Work of Breathing Caused by the Endotracheal Tube, Anesthesiology, vol.75, issue.5, pp.739-745, 1991.
DOI : 10.1097/00000542-199111000-00004

R. Mercier, D. Thomas, and . Villers, A simplified acute physiologic score for ICU patients, Crit. Care Med, vol.12, pp.975-977, 1984.

M. Dojat, L. Brochard, F. Lemaire, and A. Harf, A knowledge-based system for assisted ventilation of patients in intensive care units, International Journal of Clinical Monitoring and Computing, vol.13, issue.4, 1992.
DOI : 10.1007/BF01133619

URL : https://hal.archives-ouvertes.fr/inserm-00402430

S. Uckun, Intelligent system in patient monitoring and therapy management, International Journal of Clinical Monitoring and Computing, vol.4, issue.1, 1993.
DOI : 10.1007/BF01139876

R. F. Allen, D. Lodato, and . Dantzker, The pattern of breathing during successful and unsuccessful trials of weaning from mechanical ventilation, Am, 1986.

T. Smith and J. J. Marini, Impact of PEEP on lung mechanics and work of breathing in severe airflow obstruction, Journal of Critical Care, vol.4, issue.3, pp.1488-1499, 1988.
DOI : 10.1016/0883-9441(89)90021-X

J. H. Strickland and J. H. Hasson, A Computer-controlled Ventilator Weaning System, Chest, vol.100, issue.4, pp.1096-1099, 1991.
DOI : 10.1378/chest.100.4.1096

E. H. Shortliffe, The adolescence of AI in Medicine: Will the field come of age in the '90s?, Artificial Intelligence in Medicine, vol.5, issue.2, pp.93-106, 1993.
DOI : 10.1016/0933-3657(93)90011-Q

J. Wyatt and D. Spiegelhalter, Evaluating medical expert systems: what to test and how?, Medical Informatics, vol.9, issue.3, pp.205-217, 1990.
DOI : 10.3109/14639239009025268

P. Grogono, A. Batarekh, A. Preece, R. Shinghal, R. et al., Expert system evaluation techniques: a selected bibliography, Expert Systems, vol.15, issue.3, pp.227-239, 1991.
DOI : 10.1001/jama.242.12.1279

A. Pesenti, N. Rossi, A. Calori, G. Foti, and G. P. Rossi, Effects of Short-term Oxygenation Changes on Acute Lung Injury Patients Undergoing Pressure Support Ventilation, Chest, vol.103, issue.4, pp.1185-1189, 1993.
DOI : 10.1378/chest.103.4.1185

F. Gandia and J. J. Blanco, Evaluation of indexes predicting the outcome of ventilator weaning and value of adding supplemental inspiratory load, Intensive Care Medicine, vol.73, issue.Suppl, 1992.
DOI : 10.1007/BF01694360

S. Field, S. M. Kelly, and P. T. Macklem, The oxygen cost of breathing in patients with cardiorespiratory disease, Am. Rev. Respir. Dis, vol.126, pp.9-13, 1982.

T. E. Oh, S. Bhatt, S. Lin, R. C. Hutchinson, and J. M. Low, Plasma catecholamines and oxygen consumption during weaning from mechanical ventilation, Intensive Care Medicine, vol.92, issue.4, pp.199-203, 1991.
DOI : 10.1007/BF01709877

W. M. Macquin-mavier, Acute left ventricular dysfunction during unsuccessful weaning from mechanical ventilation, Anesthesiology, vol.69, pp.171-179, 1988.