Influence of oxygen tension on CD133 phenotype in human glioma cell cultures.
Abstract
Under standard culture conditions, tumor cells are exposed to 20% O(2), whereas the mean tumor oxygen levels within the tumor are much lower. We demonstrate, using low-passaged human tumor cell cultures established from glioma, that a reduction in the oxygen level in these cell cultures dramatically increases the percentage of CD133 expressing cells.
Origin : Files produced by the author(s)
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