PMID: identifiant
de la référence Pubmed : |
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 (10579515) |
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| titre : |
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PHMPL: a computer program for hazard estimation using a penalized likelihood method with interval-censored and left-truncated data. |
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| auteur(s) : |
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Pierre Joly ( ) 1, Luc Letenneur1, Ahmadou Alioum1, Daniel Commenges1 |
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| laboratoire : |
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| résumé : |
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The Cox model is the model of choice when analyzing right-censored and possibly left-truncated survival data. The present paper proposes a program to estimate the hazard function in a proportional hazards model and also to treat more complex observation schemes involving general censored and left-truncated data. The hazard function estimator is defined non-parametrically as the function which maximizes a penalized likelihood, and the solution is approximated using splines. The smoothing parameter is chosen using approximate cross-validation. Confidence bands for the estimator are given. As an illustration, the age-specific incidence of dementia is estimated and one of its risk factors is studied. |
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| domaine : |
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Sciences du Vivant/Santé publique et épidémiologie
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langue du texte
intégral : |
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Anglais |
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| ISSN : |
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0169-2607 |
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| type de publication : |
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Articles dans des revues avec comité de lecture |
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| journal : |
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| Computer Methods and Programs in Biomedicine (Comput Methods Programs Biomed) |
| Publisher |
Elsevier |
| ISSN |
0169-2607 |
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| Audience : |
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internationale |
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| date de publication : |
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11/1999 |
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| volume : |
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60 |
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| numéro : |
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3 |
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| page, identifiant, ... : |
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225-31 |
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| Descripteur(s) MeSH : |
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Age Factors – Aged – 80 and over – Bayes Theorem – Confidence Intervals – Dementia – Educational Status – Humans – Likelihood Functions – Mathematical Computing – Proportional Hazards Models – Risk Assessment – Risk Factors – Software |
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