| |||
Recommended dose depending on different patient profiles, defined as the dose yielding a steady-state value closest to 2.5. The last column represents the percentage of time that the corresponding dose is selected over the 1000 Monte-Carlo simulations performed, to take into account the IIV.
| Profile | Recommended dose (mg) | Probability |
|---|---|---|
| 80 year old man, 60 kg | 7.5 | 17% |
| 80 year old woman, 60 kg | 7.5 | 17% |
| 80 year old man, 50 kg | 7.5 | 16% |
| 80 year old man, 70 kg | 10 | 17% |
| 90 year old man, 60 kg | 5 | 22% |
| 80 year old man, 60 kg, after cardiac surgery | 5 | 24% |
| 80 year old man, 60 kg, given cordarone | 5 | 22% |
| 80 year old man, 60 kg, given deroxat | 5 | 19% |
