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Table 4.

Multivariate analysis of factors influencing the time to HBV-DNA undetectability (<200copies/mL)

Adjusted Hazard Ratio CI 95% p
TDF v. ADV 2.79 (1.05–7.40) 0.039
HBV load at baseline (per log10 copies/mL HBV-DNA) 0.75 (0.59–0.94) 0.01
ALT level at baseline (≥72 UI/mL = median) 0.58 (0.32–1.05) 0.07
Presence of HBe antigen in serum 0.20 (0.05–0.79) 0.02
Antivir Ther. 2008; 13(5): 705–13.